RCF1_CANTT
ID RCF1_CANTT Reviewed; 155 AA.
AC C5MAV2;
DT 05-OCT-2010, integrated into UniProtKB/Swiss-Prot.
DT 28-JUL-2009, sequence version 1.
DT 25-MAY-2022, entry version 35.
DE RecName: Full=Respiratory supercomplex factor 1, mitochondrial;
GN Name=RCF1; Synonyms=AIM31; ORFNames=CTRG_03194;
OS Candida tropicalis (strain ATCC MYA-3404 / T1) (Yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX NCBI_TaxID=294747;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-3404 / T1;
RX PubMed=19465905; DOI=10.1038/nature08064;
RA Butler G., Rasmussen M.D., Lin M.F., Santos M.A.S., Sakthikumar S.,
RA Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA Arnaud M.B., Bates S., Brown A.J.P., Brunke S., Costanzo M.C.,
RA Fitzpatrick D.A., de Groot P.W.J., Harris D., Hoyer L.L., Hube B.,
RA Klis F.M., Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M.,
RA Nikolaou E., Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F.,
RA Sherlock G., Shah P., Silverstein K.A.T., Skrzypek M.S., Soll D.,
RA Staggs R., Stansfield I., Stumpf M.P.H., Sudbery P.E., Srikantha T.,
RA Zeng Q., Berman J., Berriman M., Heitman J., Gow N.A.R., Lorenz M.C.,
RA Birren B.W., Kellis M., Cuomo C.A.;
RT "Evolution of pathogenicity and sexual reproduction in eight Candida
RT genomes.";
RL Nature 459:657-662(2009).
CC -!- FUNCTION: Cytochrome c oxidase subunit which plays a role in assembly
CC of respiratory supercomplexes. {ECO:0000250}.
CC -!- SUBUNIT: Associates with the respiratory chain complex III/complex IV
CC supercomplex. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion membrane {ECO:0000255|PROSITE-
CC ProRule:PRU00836}; Multi-pass membrane protein {ECO:0000255|PROSITE-
CC ProRule:PRU00836}.
CC -!- SIMILARITY: Belongs to the RCF1 family. {ECO:0000305}.
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DR EMBL; GG692398; EER32769.1; -; Genomic_DNA.
DR RefSeq; XP_002548897.1; XM_002548851.1.
DR AlphaFoldDB; C5MAV2; -.
DR STRING; 5482.XP_002548897.1; -.
DR EnsemblFungi; EER32769; EER32769; CTRG_03194.
DR GeneID; 8299822; -.
DR KEGG; ctp:CTRG_03194; -.
DR VEuPathDB; FungiDB:CTRG_03194; -.
DR eggNOG; KOG4431; Eukaryota.
DR HOGENOM; CLU_087356_1_0_1; -.
DR OrthoDB; 1307900at2759; -.
DR Proteomes; UP000002037; Unassembled WGS sequence.
DR GO; GO:0031305; C:integral component of mitochondrial inner membrane; IEA:EnsemblFungi.
DR GO; GO:0005746; C:mitochondrial respirasome; IEA:EnsemblFungi.
DR GO; GO:0033617; P:mitochondrial cytochrome c oxidase assembly; IEA:EnsemblFungi.
DR GO; GO:0097250; P:mitochondrial respirasome assembly; IEA:EnsemblFungi.
DR GO; GO:0010155; P:regulation of proton transport; IEA:EnsemblFungi.
DR InterPro; IPR007667; Hypoxia_induced_domain.
DR Pfam; PF04588; HIG_1_N; 1.
DR PROSITE; PS51503; HIG1; 1.
PE 3: Inferred from homology;
KW Coiled coil; Membrane; Mitochondrion; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..155
FT /note="Respiratory supercomplex factor 1, mitochondrial"
FT /id="PRO_0000399627"
FT TRANSMEM 31..48
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00836"
FT TRANSMEM 61..83
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00836"
FT DOMAIN 3..94
FT /note="HIG1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00836"
FT COILED 86..147
FT /evidence="ECO:0000255"
SQ SEQUENCE 155 AA; 18016 MW; 13299AE623FEE653 CRC64;
MSGLPSSVAF GEEEEPDLLD KMWEKSKQQP LVPIGSLLTA GAVFLAARSM KRGEKVKTQI
YFRYRIGFQL ATLAALVLGG MYYGTETKEY KQSREEKLRE KAKQREKLWI EELERRDAII
QARKQRLEES KKELRELAKQ GFEEEQNSQQ SQEKN
