RCF1_COCP7
ID RCF1_COCP7 Reviewed; 180 AA.
AC C5P447;
DT 05-OCT-2010, integrated into UniProtKB/Swiss-Prot.
DT 01-SEP-2009, sequence version 1.
DT 25-MAY-2022, entry version 39.
DE RecName: Full=Respiratory supercomplex factor 1, mitochondrial;
GN Name=RCF1; Synonyms=AIM31; ORFNames=CPC735_063380;
OS Coccidioides posadasii (strain C735) (Valley fever fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Onygenaceae; Coccidioides.
OX NCBI_TaxID=222929;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C735;
RX PubMed=19717792; DOI=10.1101/gr.087551.108;
RA Sharpton T.J., Stajich J.E., Rounsley S.D., Gardner M.J., Wortman J.R.,
RA Jordar V.S., Maiti R., Kodira C.D., Neafsey D.E., Zeng Q., Hung C.-Y.,
RA McMahan C., Muszewska A., Grynberg M., Mandel M.A., Kellner E.M.,
RA Barker B.M., Galgiani J.N., Orbach M.J., Kirkland T.N., Cole G.T.,
RA Henn M.R., Birren B.W., Taylor J.W.;
RT "Comparative genomic analyses of the human fungal pathogens Coccidioides
RT and their relatives.";
RL Genome Res. 19:1722-1731(2009).
CC -!- FUNCTION: Cytochrome c oxidase subunit which plays a role in assembly
CC of respiratory supercomplexes. {ECO:0000250}.
CC -!- SUBUNIT: Associates with the respiratory chain complex III/complex IV
CC supercomplex. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion membrane {ECO:0000255|PROSITE-
CC ProRule:PRU00836}; Multi-pass membrane protein {ECO:0000255|PROSITE-
CC ProRule:PRU00836}.
CC -!- SIMILARITY: Belongs to the RCF1 family. {ECO:0000305}.
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DR EMBL; ACFW01000015; EER28465.1; -; Genomic_DNA.
DR RefSeq; XP_003070610.1; XM_003070564.1.
DR AlphaFoldDB; C5P447; -.
DR EnsemblFungi; EER28465; EER28465; CPC735_063380.
DR GeneID; 9696105; -.
DR KEGG; cpw:CPC735_063380; -.
DR VEuPathDB; FungiDB:CPC735_063380; -.
DR HOGENOM; CLU_087356_0_2_1; -.
DR Proteomes; UP000009084; Unassembled WGS sequence.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR007667; Hypoxia_induced_domain.
DR Pfam; PF04588; HIG_1_N; 1.
DR PROSITE; PS51503; HIG1; 1.
PE 3: Inferred from homology;
KW Coiled coil; Membrane; Mitochondrion; Transmembrane; Transmembrane helix.
FT CHAIN 1..180
FT /note="Respiratory supercomplex factor 1, mitochondrial"
FT /id="PRO_0000399630"
FT TRANSMEM 34..50
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00836"
FT TRANSMEM 69..86
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00836"
FT DOMAIN 6..97
FT /note="HIG1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00836"
FT REGION 135..165
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 84..111
FT /evidence="ECO:0000255"
SQ SEQUENCE 180 AA; 20669 MW; A9E4E533154FA212 CRC64;
MSDKPLPSSF DSDPEFFEEN PWVKLRRRLR EEPLIPLGCA ATSYALWRAY KSMKAGDSDQ
LNRMFRYRIY AQAFTLVAVV VGGIYYKSER AQRKELERAM EEKKSQAKRD AWLRELEIRD
QEDRDWRERH AAVERAAKEA GMKPKDVSKG LAGESAGNQE GEAKSNVGVL DAVKNLVKEK
