ID   RCF1_KLULA              Reviewed;         158 AA.
AC   Q6CWT4;
DT   05-OCT-2010, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   25-MAY-2022, entry version 78.
DE   RecName: Full=Respiratory supercomplex factor 1, mitochondrial;
GN   Name=RCF1; Synonyms=AIM31; OrderedLocusNames=KLLA0B01672g;
OS   Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 /
OS   NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Kluyveromyces.
OX   NCBI_TaxID=284590;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Cytochrome c oxidase subunit which plays a role in assembly
CC       of respiratory supercomplexes. {ECO:0000250}.
CC   -!- SUBUNIT: Associates with the respiratory chain complex III/complex IV
CC       supercomplex. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion membrane {ECO:0000255|PROSITE-
CC       ProRule:PRU00836}; Multi-pass membrane protein {ECO:0000255|PROSITE-
CC       ProRule:PRU00836}.
CC   -!- SIMILARITY: Belongs to the RCF1 family. {ECO:0000305}.
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DR   EMBL; CR382122; CAH01998.1; -; Genomic_DNA.
DR   RefSeq; XP_451605.1; XM_451605.1.
DR   AlphaFoldDB; Q6CWT4; -.
DR   SMR; Q6CWT4; -.
DR   STRING; 28985.XP_451605.1; -.
DR   EnsemblFungi; CAH01998; CAH01998; KLLA0_B01672g.
DR   GeneID; 2897415; -.
DR   KEGG; kla:KLLA0_B01672g; -.
DR   eggNOG; KOG4431; Eukaryota.
DR   HOGENOM; CLU_087356_1_0_1; -.
DR   InParanoid; Q6CWT4; -.
DR   OMA; SVEMNKM; -.
DR   Proteomes; UP000000598; Chromosome B.
DR   GO; GO:0031305; C:integral component of mitochondrial inner membrane; IEA:EnsemblFungi.
DR   GO; GO:0005746; C:mitochondrial respirasome; IEA:EnsemblFungi.
DR   GO; GO:0033617; P:mitochondrial cytochrome c oxidase assembly; IEA:EnsemblFungi.
DR   GO; GO:0097250; P:mitochondrial respirasome assembly; IEA:EnsemblFungi.
DR   GO; GO:0010155; P:regulation of proton transport; IEA:EnsemblFungi.
DR   InterPro; IPR007667; Hypoxia_induced_domain.
DR   Pfam; PF04588; HIG_1_N; 1.
DR   PROSITE; PS51503; HIG1; 1.
PE   3: Inferred from homology;
KW   Coiled coil; Membrane; Mitochondrion; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..158
FT                   /note="Respiratory supercomplex factor 1, mitochondrial"
FT                   /id="PRO_0000399634"
FT   TRANSMEM        32..52
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00836"
FT   TRANSMEM        68..88
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00836"
FT   DOMAIN          5..96
FT                   /note="HIG1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00836"
FT   REGION          128..158
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          88..158
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   158 AA;  18566 MW;  99E6AC768E2BE560 CRC64;
     MSYLPSSFDS DADDLDEMPF LDKMIYHCKQ QPLVPLGTLA TTGAVLLAVL NVKNGNKRKA
     QIWFRWRVAL QGFTLIALVA GSYIYGTNKN ERESHEEQLR KKAKMREQLW IQELERRDEE
     TKLRRQKAEL ARQKAKEMEQ ETSKLQQELK DLEERLKK