RCF1_LACTC
ID RCF1_LACTC Reviewed; 160 AA.
AC C5DLZ7;
DT 05-OCT-2010, integrated into UniProtKB/Swiss-Prot.
DT 28-JUL-2009, sequence version 1.
DT 25-MAY-2022, entry version 47.
DE RecName: Full=Respiratory supercomplex factor 1, mitochondrial;
GN Name=RCF1; Synonyms=AIM31; OrderedLocusNames=KLTH0G04774g;
OS Lachancea thermotolerans (strain ATCC 56472 / CBS 6340 / NRRL Y-8284)
OS (Yeast) (Kluyveromyces thermotolerans).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Lachancea.
OX NCBI_TaxID=559295;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 56472 / CBS 6340 / NRRL Y-8284;
RX PubMed=19525356; DOI=10.1101/gr.091546.109;
RG The Genolevures Consortium;
RA Souciet J.-L., Dujon B., Gaillardin C., Johnston M., Baret P.V.,
RA Cliften P., Sherman D.J., Weissenbach J., Westhof E., Wincker P., Jubin C.,
RA Poulain J., Barbe V., Segurens B., Artiguenave F., Anthouard V.,
RA Vacherie B., Val M.-E., Fulton R.S., Minx P., Wilson R., Durrens P.,
RA Jean G., Marck C., Martin T., Nikolski M., Rolland T., Seret M.-L.,
RA Casaregola S., Despons L., Fairhead C., Fischer G., Lafontaine I., Leh V.,
RA Lemaire M., de Montigny J., Neuveglise C., Thierry A., Blanc-Lenfle I.,
RA Bleykasten C., Diffels J., Fritsch E., Frangeul L., Goeffon A.,
RA Jauniaux N., Kachouri-Lafond R., Payen C., Potier S., Pribylova L.,
RA Ozanne C., Richard G.-F., Sacerdot C., Straub M.-L., Talla E.;
RT "Comparative genomics of protoploid Saccharomycetaceae.";
RL Genome Res. 19:1696-1709(2009).
CC -!- FUNCTION: Cytochrome c oxidase subunit which plays a role in assembly
CC of respiratory supercomplexes. {ECO:0000250}.
CC -!- SUBUNIT: Associates with the respiratory chain complex III/complex IV
CC supercomplex. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion membrane {ECO:0000255|PROSITE-
CC ProRule:PRU00836}; Multi-pass membrane protein {ECO:0000255|PROSITE-
CC ProRule:PRU00836}.
CC -!- SIMILARITY: Belongs to the RCF1 family. {ECO:0000305}.
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DR EMBL; CU928171; CAR24808.1; -; Genomic_DNA.
DR RefSeq; XP_002555245.1; XM_002555199.1.
DR AlphaFoldDB; C5DLZ7; -.
DR SMR; C5DLZ7; -.
DR STRING; 559295.C5DLZ7; -.
DR EnsemblFungi; CAR24808; CAR24808; KLTH0G04774g.
DR GeneID; 8293511; -.
DR KEGG; lth:KLTH0G04774g; -.
DR eggNOG; KOG4431; Eukaryota.
DR HOGENOM; CLU_087356_1_0_1; -.
DR InParanoid; C5DLZ7; -.
DR OMA; SVEMNKM; -.
DR OrthoDB; 1307900at2759; -.
DR Proteomes; UP000002036; Chromosome G.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR007667; Hypoxia_induced_domain.
DR Pfam; PF04588; HIG_1_N; 1.
DR PROSITE; PS51503; HIG1; 1.
PE 3: Inferred from homology;
KW Coiled coil; Membrane; Mitochondrion; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..160
FT /note="Respiratory supercomplex factor 1, mitochondrial"
FT /id="PRO_0000399636"
FT TRANSMEM 33..50
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00836"
FT TRANSMEM 63..85
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00836"
FT DOMAIN 5..96
FT /note="HIG1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00836"
FT REGION 135..160
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 86..160
FT /evidence="ECO:0000255"
FT COMPBIAS 145..160
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 160 AA; 18305 MW; 37F44ED05A706839 CRC64;
MSHLPSSFDG AEQDVDEMTF LEKMTFHCKQ QPLVPLGTLA TTVAVILAAQ NVRSGNKRKA
QKYFRWRVGL QGATLVALVA GSFIYGTSQK ERQSKEDALR EKAKLREKLW IQELERRDEE
TQLRKKRAEL ARSRAKELEQ ETQGLQQELR DLQAKTSSSK
