RCF1_LODEL
ID RCF1_LODEL Reviewed; 154 AA.
AC A5E2M7;
DT 05-OCT-2010, integrated into UniProtKB/Swiss-Prot.
DT 12-JUN-2007, sequence version 1.
DT 03-AUG-2022, entry version 52.
DE RecName: Full=Respiratory supercomplex factor 1, mitochondrial;
GN Name=RCF1; Synonyms=AIM31; ORFNames=LELG_03864;
OS Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC
OS 1676 / NRRL YB-4239) (Yeast) (Saccharomyces elongisporus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade;
OC Lodderomyces.
OX NCBI_TaxID=379508;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 11503 / BCRC 21390 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL
RC YB-4239;
RX PubMed=19465905; DOI=10.1038/nature08064;
RA Butler G., Rasmussen M.D., Lin M.F., Santos M.A.S., Sakthikumar S.,
RA Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA Arnaud M.B., Bates S., Brown A.J.P., Brunke S., Costanzo M.C.,
RA Fitzpatrick D.A., de Groot P.W.J., Harris D., Hoyer L.L., Hube B.,
RA Klis F.M., Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M.,
RA Nikolaou E., Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F.,
RA Sherlock G., Shah P., Silverstein K.A.T., Skrzypek M.S., Soll D.,
RA Staggs R., Stansfield I., Stumpf M.P.H., Sudbery P.E., Srikantha T.,
RA Zeng Q., Berman J., Berriman M., Heitman J., Gow N.A.R., Lorenz M.C.,
RA Birren B.W., Kellis M., Cuomo C.A.;
RT "Evolution of pathogenicity and sexual reproduction in eight Candida
RT genomes.";
RL Nature 459:657-662(2009).
CC -!- FUNCTION: Cytochrome c oxidase subunit which plays a role in assembly
CC of respiratory supercomplexes. {ECO:0000250}.
CC -!- SUBUNIT: Associates with the respiratory chain complex III/complex IV
CC supercomplex. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion membrane {ECO:0000255|PROSITE-
CC ProRule:PRU00836}; Multi-pass membrane protein {ECO:0000255|PROSITE-
CC ProRule:PRU00836}.
CC -!- SIMILARITY: Belongs to the RCF1 family. {ECO:0000305}.
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DR EMBL; CH981528; EDK45685.1; -; Genomic_DNA.
DR RefSeq; XP_001524832.1; XM_001524782.1.
DR AlphaFoldDB; A5E2M7; -.
DR STRING; 379508.A5E2M7; -.
DR PRIDE; A5E2M7; -.
DR EnsemblFungi; EDK45685; EDK45685; LELG_03864.
DR GeneID; 5232110; -.
DR KEGG; lel:LELG_03864; -.
DR VEuPathDB; FungiDB:LELG_03864; -.
DR eggNOG; KOG4431; Eukaryota.
DR HOGENOM; CLU_087356_1_0_1; -.
DR InParanoid; A5E2M7; -.
DR OMA; REQLWIE; -.
DR OrthoDB; 1307900at2759; -.
DR Proteomes; UP000001996; Unassembled WGS sequence.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR007667; Hypoxia_induced_domain.
DR Pfam; PF04588; HIG_1_N; 1.
DR PROSITE; PS51503; HIG1; 1.
PE 3: Inferred from homology;
KW Coiled coil; Membrane; Mitochondrion; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..154
FT /note="Respiratory supercomplex factor 1, mitochondrial"
FT /id="PRO_0000399637"
FT TRANSMEM 31..48
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00836"
FT TRANSMEM 63..85
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00836"
FT DOMAIN 4..95
FT /note="HIG1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00836"
FT COILED 89..144
FT /evidence="ECO:0000255"
SQ SEQUENCE 154 AA; 17755 MW; 6FB0F3A3538A0E78 CRC64;
MTQRLPSSMS FGEEEEPDVL QKMMQKCKEQ PFVPIGSLLT AGAVILAARS MKRGEKLKTQ
KYFRYRIGFQ LATLIALVAG GVTLGQSSLE QKKTKEDQLR EKAKLREKLW VEELERRDAI
IQARKQRLEE SKKELRDLAK QGFEDEREVD QGKK
