RCF1_NEOFI
ID RCF1_NEOFI Reviewed; 181 AA.
AC A1CXG2;
DT 05-OCT-2010, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2007, sequence version 1.
DT 25-MAY-2022, entry version 64.
DE RecName: Full=Respiratory supercomplex factor 1, mitochondrial;
GN Name=rcf1; Synonyms=aim31; ORFNames=NFIA_108070;
OS Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164
OS / JCM 1740 / NRRL 181 / WB 181) (Aspergillus fischerianus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Fumigati.
OX NCBI_TaxID=331117;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181
RC / WB 181;
RX PubMed=18404212; DOI=10.1371/journal.pgen.1000046;
RA Fedorova N.D., Khaldi N., Joardar V.S., Maiti R., Amedeo P., Anderson M.J.,
RA Crabtree J., Silva J.C., Badger J.H., Albarraq A., Angiuoli S., Bussey H.,
RA Bowyer P., Cotty P.J., Dyer P.S., Egan A., Galens K., Fraser-Liggett C.M.,
RA Haas B.J., Inman J.M., Kent R., Lemieux S., Malavazi I., Orvis J.,
RA Roemer T., Ronning C.M., Sundaram J.P., Sutton G., Turner G., Venter J.C.,
RA White O.R., Whitty B.R., Youngman P., Wolfe K.H., Goldman G.H.,
RA Wortman J.R., Jiang B., Denning D.W., Nierman W.C.;
RT "Genomic islands in the pathogenic filamentous fungus Aspergillus
RT fumigatus.";
RL PLoS Genet. 4:E1000046-E1000046(2008).
CC -!- FUNCTION: Cytochrome c oxidase subunit which plays a role in assembly
CC of respiratory supercomplexes. {ECO:0000250}.
CC -!- SUBUNIT: Associates with the respiratory chain complex III/complex IV
CC supercomplex. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion membrane {ECO:0000255|PROSITE-
CC ProRule:PRU00836}; Multi-pass membrane protein {ECO:0000255|PROSITE-
CC ProRule:PRU00836}.
CC -!- SIMILARITY: Belongs to the RCF1 family. {ECO:0000305}.
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DR EMBL; DS027685; EAW25314.1; -; Genomic_DNA.
DR RefSeq; XP_001267211.1; XM_001267210.1.
DR AlphaFoldDB; A1CXG2; -.
DR STRING; 36630.CADNFIAP00009716; -.
DR EnsemblFungi; EAW25314; EAW25314; NFIA_108070.
DR GeneID; 4593306; -.
DR KEGG; nfi:NFIA_108070; -.
DR VEuPathDB; FungiDB:NFIA_108070; -.
DR eggNOG; KOG4431; Eukaryota.
DR HOGENOM; CLU_087356_0_2_1; -.
DR OMA; SVEMNKM; -.
DR OrthoDB; 1307900at2759; -.
DR Proteomes; UP000006702; Unassembled WGS sequence.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR007667; Hypoxia_induced_domain.
DR Pfam; PF04588; HIG_1_N; 1.
DR PROSITE; PS51503; HIG1; 1.
PE 3: Inferred from homology;
KW Coiled coil; Membrane; Mitochondrion; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..181
FT /note="Respiratory supercomplex factor 1, mitochondrial"
FT /id="PRO_0000399641"
FT TRANSMEM 33..49
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00836"
FT TRANSMEM 69..86
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00836"
FT DOMAIN 6..97
FT /note="HIG1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00836"
FT REGION 136..160
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 181 AA; 21099 MW; 00A96257F0E5B145 CRC64;
MLNEPLPSSM EDNPQFKEET SLQKFRRRLK EEPLIPLGCA ATCYALYRAY RSMKAGDSVE
MNKMFRARIY AQFFTLVAVV AGGMYFKTER QQRREFEKMV EQRKAQEKRD AWLRELEIRD
KEDKDWRERH AAIEAAAKEA GKRPAPNKIP EQDAARSAIE PADEKSIGVL AAVRDLWMQQ
K
