RCF1_PICGU
ID RCF1_PICGU Reviewed; 150 AA.
AC A5DHC2;
DT 05-OCT-2010, integrated into UniProtKB/Swiss-Prot.
DT 12-JUN-2007, sequence version 1.
DT 03-AUG-2022, entry version 47.
DE RecName: Full=Respiratory supercomplex factor 1, mitochondrial;
GN Name=RCF1; Synonyms=AIM31; ORFNames=PGUG_02673;
OS Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539
OS / NBRC 10279 / NRRL Y-324) (Yeast) (Candida guilliermondii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Meyerozyma.
OX NCBI_TaxID=294746;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324;
RX PubMed=19465905; DOI=10.1038/nature08064;
RA Butler G., Rasmussen M.D., Lin M.F., Santos M.A.S., Sakthikumar S.,
RA Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA Arnaud M.B., Bates S., Brown A.J.P., Brunke S., Costanzo M.C.,
RA Fitzpatrick D.A., de Groot P.W.J., Harris D., Hoyer L.L., Hube B.,
RA Klis F.M., Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M.,
RA Nikolaou E., Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F.,
RA Sherlock G., Shah P., Silverstein K.A.T., Skrzypek M.S., Soll D.,
RA Staggs R., Stansfield I., Stumpf M.P.H., Sudbery P.E., Srikantha T.,
RA Zeng Q., Berman J., Berriman M., Heitman J., Gow N.A.R., Lorenz M.C.,
RA Birren B.W., Kellis M., Cuomo C.A.;
RT "Evolution of pathogenicity and sexual reproduction in eight Candida
RT genomes.";
RL Nature 459:657-662(2009).
CC -!- FUNCTION: Cytochrome c oxidase subunit which plays a role in assembly
CC of respiratory supercomplexes. {ECO:0000250}.
CC -!- SUBUNIT: Associates with the respiratory chain complex III/complex IV
CC supercomplex. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion membrane {ECO:0000255|PROSITE-
CC ProRule:PRU00836}; Multi-pass membrane protein {ECO:0000255|PROSITE-
CC ProRule:PRU00836}.
CC -!- SIMILARITY: Belongs to the RCF1 family. {ECO:0000305}.
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DR EMBL; CH408157; EDK38575.1; -; Genomic_DNA.
DR RefSeq; XP_001484944.1; XM_001484894.1.
DR AlphaFoldDB; A5DHC2; -.
DR SMR; A5DHC2; -.
DR STRING; 4929.XP_001484944.1; -.
DR EnsemblFungi; EDK38575; EDK38575; PGUG_02673.
DR GeneID; 5126646; -.
DR KEGG; pgu:PGUG_02673; -.
DR VEuPathDB; FungiDB:PGUG_02673; -.
DR eggNOG; KOG4431; Eukaryota.
DR HOGENOM; CLU_087356_1_0_1; -.
DR InParanoid; A5DHC2; -.
DR OMA; REQLWIE; -.
DR OrthoDB; 1307900at2759; -.
DR Proteomes; UP000001997; Unassembled WGS sequence.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR007667; Hypoxia_induced_domain.
DR Pfam; PF04588; HIG_1_N; 1.
DR PROSITE; PS51503; HIG1; 1.
PE 3: Inferred from homology;
KW Coiled coil; Membrane; Mitochondrion; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..150
FT /note="Respiratory supercomplex factor 1, mitochondrial"
FT /id="PRO_0000399649"
FT TRANSMEM 15..32
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00836"
FT TRANSMEM 45..67
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00836"
FT DOMAIN 1..79
FT /note="HIG1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00836"
FT REGION 126..150
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 71..150
FT /evidence="ECO:0000255"
SQ SEQUENCE 150 AA; 17565 MW; D9819E7011EE559E CRC64;
MDIIQKMVFK SKQQPLVPIG ALATTGAIIL ASKSIRRGDR IKTQIYFRYR IGFQLLTLVA
LVAGGLYYQT ETAQQKQTRE EKLRDKAKLR EKLWIEELER RDAVIQERKK RLEESKAELL
EVAQQGFEEA RETETREAQL KKEEIEEKEN
