RCF1_UNCRE
ID RCF1_UNCRE Reviewed; 185 AA.
AC C4JHR1;
DT 05-OCT-2010, integrated into UniProtKB/Swiss-Prot.
DT 07-JUL-2009, sequence version 1.
DT 25-MAY-2022, entry version 38.
DE RecName: Full=Respiratory supercomplex factor 1, mitochondrial;
GN Name=RCF1; Synonyms=AIM31; ORFNames=UREG_02747;
OS Uncinocarpus reesii (strain UAMH 1704).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Onygenaceae; Uncinocarpus.
OX NCBI_TaxID=336963;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UAMH 1704;
RX PubMed=19717792; DOI=10.1101/gr.087551.108;
RA Sharpton T.J., Stajich J.E., Rounsley S.D., Gardner M.J., Wortman J.R.,
RA Jordar V.S., Maiti R., Kodira C.D., Neafsey D.E., Zeng Q., Hung C.-Y.,
RA McMahan C., Muszewska A., Grynberg M., Mandel M.A., Kellner E.M.,
RA Barker B.M., Galgiani J.N., Orbach M.J., Kirkland T.N., Cole G.T.,
RA Henn M.R., Birren B.W., Taylor J.W.;
RT "Comparative genomic analyses of the human fungal pathogens Coccidioides
RT and their relatives.";
RL Genome Res. 19:1722-1731(2009).
CC -!- FUNCTION: Cytochrome c oxidase subunit which plays a role in assembly
CC of respiratory supercomplexes. {ECO:0000250}.
CC -!- SUBUNIT: Associates with the respiratory chain complex III/complex IV
CC supercomplex. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion membrane {ECO:0000255|PROSITE-
CC ProRule:PRU00836}; Multi-pass membrane protein {ECO:0000255|PROSITE-
CC ProRule:PRU00836}.
CC -!- SIMILARITY: Belongs to the RCF1 family. {ECO:0000305}.
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DR EMBL; CH476615; EEP77898.1; -; Genomic_DNA.
DR RefSeq; XP_002543231.1; XM_002543185.1.
DR AlphaFoldDB; C4JHR1; -.
DR STRING; 33188.XP_002543231.1; -.
DR EnsemblFungi; EEP77898; EEP77898; UREG_02747.
DR GeneID; 8437534; -.
DR KEGG; ure:UREG_02747; -.
DR VEuPathDB; FungiDB:UREG_02747; -.
DR eggNOG; KOG4431; Eukaryota.
DR HOGENOM; CLU_087356_0_2_1; -.
DR InParanoid; C4JHR1; -.
DR OrthoDB; 1307900at2759; -.
DR Proteomes; UP000002058; Unassembled WGS sequence.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR007667; Hypoxia_induced_domain.
DR Pfam; PF04588; HIG_1_N; 1.
DR PROSITE; PS51503; HIG1; 1.
PE 3: Inferred from homology;
KW Coiled coil; Membrane; Mitochondrion; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..185
FT /note="Respiratory supercomplex factor 1, mitochondrial"
FT /id="PRO_0000399662"
FT TRANSMEM 16..33
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00836"
FT TRANSMEM 75..92
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00836"
FT DOMAIN 12..103
FT /note="HIG1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00836"
FT REGION 128..185
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 92..117
FT /evidence="ECO:0000255"
FT COMPBIAS 128..170
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 185 AA; 20782 MW; C4D1A55AF5F318FD CRC64;
MSDRPLPSSF DPYNSYLLRI LLCSVLPVQF LAVHELITRP IPAGCLATSY ALLRAYKSMK
AGDSAQLNRM FRFRIYAQAF TLLAGVGGGF YYQAERAQRK ELERAVADKK AQAKRDAWLR
ELEIRDQEDR EWRERHEAVG KAAKEAGNKP KEANLDAPKV PTKESEEAKP TGGILDAVKS
LGKEK
