ID   RCF1_YEAS1              Reviewed;         159 AA.
AC   B3LLM2;
DT   05-OCT-2010, integrated into UniProtKB/Swiss-Prot.
DT   02-SEP-2008, sequence version 1.
DT   25-MAY-2022, entry version 39.
DE   RecName: Full=Respiratory supercomplex factor 1, mitochondrial;
DE   AltName: Full=Altered inheritance of mitochondria protein 31;
GN   Name=RCF1; Synonyms=AIM31; ORFNames=SCRG_01865;
OS   Saccharomyces cerevisiae (strain RM11-1a) (Baker's yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=285006;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RM11-1a;
RG   The Broad Institute Genome Sequencing Platform;
RA   Birren B.W., Lander E.S., Galagan J.E., Nusbaum C., Devon K., Cuomo C.,
RA   Jaffe D.B., Butler J., Alvarez P., Gnerre S., Grabherr M., Kleber M.,
RA   Mauceli E.W., Brockman W., MacCallum I.A., Rounsley S., Young S.K.,
RA   LaButti K., Pushparaj V., DeCaprio D., Crawford M., Koehrsen M., Engels R.,
RA   Montgomery P., Pearson M., Howarth C., Larson L., Luoma S., White J.,
RA   O'Leary S., Kodira C.D., Zeng Q., Yandava C., Alvarado L., Pratt S.,
RA   Kruglyak L.;
RT   "Annotation of the Saccharomyces cerevisiae RM11-1a genome.";
RL   Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Cytochrome c oxidase subunit required for growth under
CC       hypoxic conditions. Involved in the assembly of the Complex III-Complex
CC       IV supercomplex, as well as in the recruitment of COX13 and RCF2 into
CC       cytochrome c oxidase. May also be required for late-stage assembly of
CC       the COX12 and COX13 subunits and for cytochrome c oxidase activity (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Associates with the respiratory chain complex III/complex IV
CC       supercomplex. Interacts with COX3. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion membrane {ECO:0000255|PROSITE-
CC       ProRule:PRU00836}; Multi-pass membrane protein {ECO:0000255|PROSITE-
CC       ProRule:PRU00836}.
CC   -!- SIMILARITY: Belongs to the RCF1 family. {ECO:0000305}.
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DR   EMBL; CH408047; EDV11475.1; -; Genomic_DNA.
DR   AlphaFoldDB; B3LLM2; -.
DR   SMR; B3LLM2; -.
DR   EnsemblFungi; EDV11475; EDV11475; SCRG_01865.
DR   HOGENOM; CLU_087356_1_0_1; -.
DR   Proteomes; UP000008335; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR007667; Hypoxia_induced_domain.
DR   Pfam; PF04588; HIG_1_N; 1.
DR   PROSITE; PS51503; HIG1; 1.
PE   3: Inferred from homology;
KW   Coiled coil; Membrane; Mitochondrion; Transmembrane; Transmembrane helix.
FT   CHAIN           1..159
FT                   /note="Respiratory supercomplex factor 1, mitochondrial"
FT                   /id="PRO_0000399656"
FT   TRANSMEM        32..52
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00836"
FT   TRANSMEM        68..88
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00836"
FT   DOMAIN          5..96
FT                   /note="HIG1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00836"
FT   COILED          88..159
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   159 AA;  18477 MW;  86E57ABA0152402B CRC64;
     MSRMPSSFDV TERDLDDMTF GERIIYHCKK QPLVPIGCLL TTGAVILAAQ NVRLGNKWKA
     QYYFRWRVGL QAATLVALVA GSFIYGTSGK ELKAKEEQLK EKAKMREKLW IQELERREEE
     TEARRKRAEL ARMKTLENEE EIKNLEKELS DLENKLGKK