ID   RCF1_YEAS8              Reviewed;         159 AA.
AC   C8ZEH4;
DT   05-OCT-2010, integrated into UniProtKB/Swiss-Prot.
DT   03-NOV-2009, sequence version 1.
DT   25-MAY-2022, entry version 38.
DE   RecName: Full=Respiratory supercomplex factor 1, mitochondrial;
DE   AltName: Full=Altered inheritance of mitochondria protein 31;
GN   Name=RCF1; Synonyms=AIM31; ORFNames=EC1118_1M3_1200g;
OS   Saccharomyces cerevisiae (strain Lalvin EC1118 / Prise de mousse) (Baker's
OS   yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=643680;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Lalvin EC1118 / Prise de mousse;
RX   PubMed=19805302; DOI=10.1073/pnas.0904673106;
RA   Novo M., Bigey F., Beyne E., Galeote V., Gavory F., Mallet S., Cambon B.,
RA   Legras J.-L., Wincker P., Casaregola S., Dequin S.;
RT   "Eukaryote-to-eukaryote gene transfer events revealed by the genome
RT   sequence of the wine yeast Saccharomyces cerevisiae EC1118.";
RL   Proc. Natl. Acad. Sci. U.S.A. 106:16333-16338(2009).
CC   -!- FUNCTION: Cytochrome c oxidase subunit required for growth under
CC       hypoxic conditions. Involved in the assembly of the Complex III-Complex
CC       IV supercomplex, as well as in the recruitment of COX13 and RCF2 into
CC       cytochrome c oxidase. May also be required for late-stage assembly of
CC       the COX12 and COX13 subunits and for cytochrome c oxidase activity (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Associates with the respiratory chain complex III/complex IV
CC       supercomplex. Interacts with COX3. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion membrane {ECO:0000255|PROSITE-
CC       ProRule:PRU00836}; Multi-pass membrane protein {ECO:0000255|PROSITE-
CC       ProRule:PRU00836}.
CC   -!- SIMILARITY: Belongs to the RCF1 family. {ECO:0000305}.
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DR   EMBL; FN393082; CAY81790.1; -; Genomic_DNA.
DR   AlphaFoldDB; C8ZEH4; -.
DR   SMR; C8ZEH4; -.
DR   EnsemblFungi; CAY81790; CAY81790; EC1118_1M3_1200g.
DR   HOGENOM; CLU_087356_1_0_1; -.
DR   Proteomes; UP000000286; Chromosome XIII, Scaffold EC1118_1M3.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR007667; Hypoxia_induced_domain.
DR   Pfam; PF04588; HIG_1_N; 1.
DR   PROSITE; PS51503; HIG1; 1.
PE   3: Inferred from homology;
KW   Coiled coil; Membrane; Mitochondrion; Transmembrane; Transmembrane helix.
FT   CHAIN           1..159
FT                   /note="Respiratory supercomplex factor 1, mitochondrial"
FT                   /id="PRO_0000399655"
FT   TRANSMEM        32..52
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00836"
FT   TRANSMEM        68..88
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00836"
FT   DOMAIN          5..96
FT                   /note="HIG1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00836"
FT   COILED          88..159
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   159 AA;  18477 MW;  86E57ABA0152402B CRC64;
     MSRMPSSFDV TERDLDDMTF GERIIYHCKK QPLVPIGCLL TTGAVILAAQ NVRLGNKWKA
     QYYFRWRVGL QAATLVALVA GSFIYGTSGK ELKAKEEQLK EKAKMREKLW IQELERREEE
     TEARRKRAEL ARMKTLENEE EIKNLEKELS DLENKLGKK