RCSA_ERWAM
ID RCSA_ERWAM Reviewed; 211 AA.
AC P20098;
DT 01-FEB-1991, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1991, sequence version 1.
DT 25-MAY-2022, entry version 84.
DE RecName: Full=Transcriptional regulatory protein RcsA {ECO:0000255|HAMAP-Rule:MF_00982};
GN Name=rcsA {ECO:0000255|HAMAP-Rule:MF_00982};
OS Erwinia amylovora (Fire blight bacteria).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Erwiniaceae; Erwinia.
OX NCBI_TaxID=552;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=T;
RX PubMed=2283503; DOI=10.1099/00221287-136-9-1799;
RA Coleman M., Pearce R., Hitchin E., Busfield F., Mansfield J.W.,
RA Roberts I.S.;
RT "Molecular cloning, expression and nucleotide sequence of the rcsA gene of
RT Erwinia amylovora, encoding a positive regulator of capsule expression:
RT evidence for a family of related capsule activator proteins.";
RL J. Gen. Microbiol. 136:1799-1806(1990).
CC -!- FUNCTION: Component of the Rcs signaling system, which controls
CC transcription of numerous genes. Binds to DNA to regulate expression of
CC genes. {ECO:0000255|HAMAP-Rule:MF_00982}.
CC -!- SIMILARITY: Belongs to the RcsA family. {ECO:0000255|HAMAP-
CC Rule:MF_00982}.
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DR EMBL; M57387; AAA24864.1; -; Genomic_DNA.
DR AlphaFoldDB; P20098; -.
DR SMR; P20098; -.
DR PHI-base; PHI:4478; -.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR GO; GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.
DR CDD; cd06170; LuxR_C_like; 1.
DR Gene3D; 1.10.10.10; -; 1.
DR HAMAP; MF_00982; RcsA; 1.
DR InterPro; IPR030866; RcsA.
DR InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR InterPro; IPR000792; Tscrpt_reg_LuxR_C.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR Pfam; PF00196; GerE; 1.
DR PRINTS; PR00038; HTHLUXR.
DR SMART; SM00421; HTH_LUXR; 1.
DR SUPFAM; SSF46894; SSF46894; 1.
DR PROSITE; PS00622; HTH_LUXR_1; 1.
DR PROSITE; PS50043; HTH_LUXR_2; 1.
PE 3: Inferred from homology;
KW DNA-binding; Sensory transduction; Transcription; Transcription regulation.
FT CHAIN 1..211
FT /note="Transcriptional regulatory protein RcsA"
FT /id="PRO_0000184182"
FT DOMAIN 135..200
FT /note="HTH luxR-type"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00982"
FT DNA_BIND 159..178
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00982"
SQ SEQUENCE 211 AA; 24349 MW; 51BC162269735C55 CRC64;
MPTIIMDSCN YTRLGLTEYM TVKGVKKKNI SLINDIAQLQ NKCQQLKPGV VLINEDCFIH
ESDASERIRK IILQHPDTLF FIFMAISNIH FEEYLYVRNN LIITSKAIKI STLDSLLNGY
FQKKLNLSVR HGTHSEVHPF TLSQTESNML KMWMSGHDTI QISDKMQIKA KTVSSHKGNI
KRKIKTHNKQ VIYHVVRLTD NVTSGIYVNE R