RD3L_HUMAN
ID RD3L_HUMAN Reviewed; 198 AA.
AC P0DJH9;
DT 16-MAY-2012, integrated into UniProtKB/Swiss-Prot.
DT 16-MAY-2012, sequence version 1.
DT 03-AUG-2022, entry version 59.
DE RecName: Full=Protein RD3-like;
DE AltName: Full=Retinal degeneration protein 3-like;
GN Name=RD3L;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=12508121; DOI=10.1038/nature01348;
RA Heilig R., Eckenberg R., Petit J.-L., Fonknechten N., Da Silva C.,
RA Cattolico L., Levy M., Barbe V., De Berardinis V., Ureta-Vidal A.,
RA Pelletier E., Vico V., Anthouard V., Rowen L., Madan A., Qin S., Sun H.,
RA Du H., Pepin K., Artiguenave F., Robert C., Cruaud C., Bruels T.,
RA Jaillon O., Friedlander L., Samson G., Brottier P., Cure S., Segurens B.,
RA Aniere F., Samain S., Crespeau H., Abbasi N., Aiach N., Boscus D.,
RA Dickhoff R., Dors M., Dubois I., Friedman C., Gouyvenoux M., James R.,
RA Madan A., Mairey-Estrada B., Mangenot S., Martins N., Menard M., Oztas S.,
RA Ratcliffe A., Shaffer T., Trask B., Vacherie B., Bellemere C., Belser C.,
RA Besnard-Gonnet M., Bartol-Mavel D., Boutard M., Briez-Silla S.,
RA Combette S., Dufosse-Laurent V., Ferron C., Lechaplais C., Louesse C.,
RA Muselet D., Magdelenat G., Pateau E., Petit E., Sirvain-Trukniewicz P.,
RA Trybou A., Vega-Czarny N., Bataille E., Bluet E., Bordelais I., Dubois M.,
RA Dumont C., Guerin T., Haffray S., Hammadi R., Muanga J., Pellouin V.,
RA Robert D., Wunderle E., Gauguet G., Roy A., Sainte-Marthe L., Verdier J.,
RA Verdier-Discala C., Hillier L.W., Fulton L., McPherson J., Matsuda F.,
RA Wilson R., Scarpelli C., Gyapay G., Wincker P., Saurin W., Quetier F.,
RA Waterston R., Hood L., Weissenbach J.;
RT "The DNA sequence and analysis of human chromosome 14.";
RL Nature 421:601-607(2003).
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DR EMBL; AL136001; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR CCDS; CCDS58338.1; -.
DR RefSeq; NP_001244197.1; NM_001257268.1.
DR AlphaFoldDB; P0DJH9; -.
DR SMR; P0DJH9; -.
DR BioGRID; 572061; 1.
DR IntAct; P0DJH9; 1.
DR STRING; 9606.ENSP00000455434; -.
DR iPTMnet; P0DJH9; -.
DR PhosphoSitePlus; P0DJH9; -.
DR BioMuta; RD3L; -.
DR DMDM; 387935359; -.
DR PaxDb; P0DJH9; -.
DR PRIDE; P0DJH9; -.
DR Antibodypedia; 71885; 5 antibodies from 5 providers.
DR DNASU; 647286; -.
DR Ensembl; ENST00000557640.2; ENSP00000455434.1; ENSG00000227729.5.
DR GeneID; 647286; -.
DR KEGG; hsa:647286; -.
DR MANE-Select; ENST00000557640.2; ENSP00000455434.1; NM_001257268.2; NP_001244197.1.
DR UCSC; uc031qqp.1; human.
DR CTD; 647286; -.
DR GeneCards; RD3L; -.
DR HGNC; HGNC:40912; RD3L.
DR HPA; ENSG00000227729; Group enriched (heart muscle, retina).
DR neXtProt; NX_P0DJH9; -.
DR VEuPathDB; HostDB:ENSG00000227729; -.
DR eggNOG; ENOG502QVRA; Eukaryota.
DR GeneTree; ENSGT00390000002089; -.
DR HOGENOM; CLU_113153_0_0_1; -.
DR InParanoid; P0DJH9; -.
DR OMA; LPYYYPV; -.
DR OrthoDB; 278674at2759; -.
DR PhylomeDB; P0DJH9; -.
DR TreeFam; TF331573; -.
DR PathwayCommons; P0DJH9; -.
DR SignaLink; P0DJH9; -.
DR BioGRID-ORCS; 647286; 10 hits in 1059 CRISPR screens.
DR GenomeRNAi; 647286; -.
DR Pharos; P0DJH9; Tdark.
DR PRO; PR:P0DJH9; -.
DR Proteomes; UP000005640; Chromosome 14.
DR RNAct; P0DJH9; protein.
DR Bgee; ENSG00000227729; Expressed in apex of heart and 22 other tissues.
DR InterPro; IPR028092; RD3.
DR PANTHER; PTHR28489; PTHR28489; 1.
DR Pfam; PF14473; RD3; 1.
PE 4: Predicted;
KW Coiled coil; Reference proteome.
FT CHAIN 1..198
FT /note="Protein RD3-like"
FT /id="PRO_0000417456"
FT REGION 133..168
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 28..57
FT /evidence="ECO:0000255"
SQ SEQUENCE 198 AA; 23209 MW; 024AEE6948D083AB CRC64;
MPLFGWMKWP KNDSYKPTHY PGSDIVTKTL LRELKWHLKE RERLIQEIEN EQKVKKTGVD
YNWLRNYQNP HTTIPVTEQR QLEVLCSQVQ PCQTGTILSR FREVLAENDV LPWEIVYIFK
QVLKDFLSSS DRGSEQEDLE DSGSMDCSAP SVIQGDSSKR ADKDEIPTIS SYVDKNTKDR
FPVFSHRIWN LPYYHPSS