RDM1_DANRE
ID RDM1_DANRE Reviewed; 280 AA.
AC Q5U3G4;
DT 11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT 07-DEC-2004, sequence version 1.
DT 03-AUG-2022, entry version 88.
DE RecName: Full=RAD52 motif-containing protein 1;
GN Name=rdm1; ORFNames=zgc:103564;
OS Danio rerio (Zebrafish) (Brachydanio rerio).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Danionidae; Danioninae; Danio.
OX NCBI_TaxID=7955;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Ovary;
RG NIH - Zebrafish Gene Collection (ZGC) project;
RL Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: May confer resistance to the antitumor agent cisplatin. Binds
CC to DNA and RNA (By similarity). {ECO:0000250}.
CC -!- SUBUNIT: Homodimer. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus. Cytoplasm. Nucleus, nucleolus
CC {ECO:0000250}.
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DR EMBL; BC085554; AAH85554.1; -; mRNA.
DR RefSeq; NP_001007334.1; NM_001007333.1.
DR AlphaFoldDB; Q5U3G4; -.
DR STRING; 7955.ENSDARP00000055675; -.
DR PaxDb; Q5U3G4; -.
DR GeneID; 492461; -.
DR KEGG; dre:492461; -.
DR CTD; 201299; -.
DR ZFIN; ZDB-GENE-041114-14; rdm1.
DR eggNOG; ENOG502RXM9; Eukaryota.
DR InParanoid; Q5U3G4; -.
DR OrthoDB; 1475838at2759; -.
DR PhylomeDB; Q5U3G4; -.
DR PRO; PR:Q5U3G4; -.
DR Proteomes; UP000000437; Genome assembly.
DR Proteomes; UP000814640; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005730; C:nucleolus; IBA:GO_Central.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR CDD; cd12364; RRM_RDM1; 1.
DR Gene3D; 3.30.70.330; -; 1.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR040224; RDM1.
DR InterPro; IPR034200; RDM1_RRM.
DR InterPro; IPR000504; RRM_dom.
DR PANTHER; PTHR31164; PTHR31164; 1.
DR SUPFAM; SSF54928; SSF54928; 1.
DR PROSITE; PS50102; RRM; 1.
PE 2: Evidence at transcript level;
KW Cytoplasm; DNA-binding; Nucleus; Reference proteome; RNA-binding.
FT CHAIN 1..280
FT /note="RAD52 motif-containing protein 1"
FT /id="PRO_0000299532"
FT DOMAIN 18..101
FT /note="RRM"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
SQ SEQUENCE 280 AA; 31526 MW; 287D62CE4DAA7800 CRC64;
MDIEVDIIEF KVPLENNKTI FIWDIQPTFT EAYIYESLWS VYSAFGDLYL LKVCPNATVA
EPGFYALVKF YSSAQASKAQ RATDKQCLFQ SSPLKVRLST KQNLSFYSSK PLCLSKCHNL
ANHYLGFGGW TTRIVTLKDL SNCVDAGCQE ETGDQGVLLK YGCIMELSFP HHGMSCQGVG
VAEEVLDSDQ DPEEKLRKRG ALMKRAKDKA MEVAFEKVLL LILGNGKVAI EIKIDPDEIV
PEENSERVIK VNDISWTHIE SADSNAEEDF LWDLTEDLPY