ID   RDRP_LSV                Reviewed;          40 AA.
AC   P27328;
DT   01-AUG-1992, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1992, sequence version 1.
DT   23-FEB-2022, entry version 59.
DE   RecName: Full=RNA replication protein;
DE   AltName: Full=ORF 1 protein;
DE   Includes:
DE     RecName: Full=RNA-directed RNA polymerase;
DE              EC=2.7.7.48;
DE   Includes:
DE     RecName: Full=Helicase;
DE              EC=3.6.4.13;
DE   Flags: Fragment;
OS   Lily symptomless virus (LSV).
OC   Viruses; Riboviria; Orthornavirae; Kitrinoviricota; Alsuviricetes;
OC   Tymovirales; Betaflexiviridae; Quinvirinae; Carlavirus.
OX   NCBI_TaxID=12173;
OH   NCBI_TaxID=4688; Lilium.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=2129538; DOI=10.1099/0022-1317-71-4-917;
RA   Memelink J., van der Vlugt C.I.M., Linthorst H.J.M., Derks A.F.L.M.,
RA   Asjes C.J., Bol J.F.;
RT   "Homologies between the genomes of a carlavirus (lily symptomless virus)
RT   and a potexvirus (lily virus X) from lily plants.";
RL   J. Gen. Virol. 71:917-924(1990).
CC   -!- FUNCTION: RNA replication. The central part of this protein possibly
CC       functions as an ATP-binding helicase.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC         RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC         COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC         EC=2.7.7.48;
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13;
CC   -!- SIMILARITY: Belongs to the potexviruses/carlaviruses RNA replication
CC       protein family. {ECO:0000305}.
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DR   EMBL; X15343; CAA33397.1; -; Genomic_RNA.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR   GO; GO:0003724; F:RNA helicase activity; IEA:UniProtKB-EC.
DR   GO; GO:0003968; F:RNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-KW.
PE   3: Inferred from homology;
KW   ATP-binding; Helicase; Hydrolase; Multifunctional enzyme;
KW   Nucleotide-binding; Nucleotidyltransferase; RNA-directed RNA polymerase;
KW   Transferase; Viral RNA replication.
FT   CHAIN           <1..40
FT                   /note="RNA replication protein"
FT                   /id="PRO_0000222561"
FT   NON_TER         1
SQ   SEQUENCE   40 AA;  4897 MW;  F6ABC5B3F18119C7 CRC64;
     ARERMDEEEL EAFYNCVRII VKNKHLLKSD VRNVYEEQLD