ID   RDRP_OUMVV              Reviewed;         860 AA.
AC   B3VML1;
DT   30-NOV-2010, integrated into UniProtKB/Swiss-Prot.
DT   02-SEP-2008, sequence version 1.
DT   29-SEP-2021, entry version 30.
DE   RecName: Full=RNA-dependent RNA polymerase;
DE            EC=2.7.7.48;
OS   Ourmia melon virus (isolate Melon/Iran/VE9) (OuMV).
OC   Viruses; Riboviria; Orthornavirae; Lenarviricota; Miaviricetes;
OC   Ourlivirales; Botourmiaviridae; Ourmiavirus.
OX   NCBI_TaxID=652838;
OH   NCBI_TaxID=3656; Cucumis melo (Muskmelon).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=19535502; DOI=10.1099/vir.0.013086-0;
RA   Rastgou M., Habibi M.K., Izadpanah K., Masenga V., Milne R.G., Wolf Y.I.,
RA   Koonin E.V., Turina M.;
RT   "Molecular characterization of the plant virus genus Ourmiavirus and
RT   evidence of inter-kingdom reassortment of viral genome segments as its
RT   possible route of origin.";
RL   J. Gen. Virol. 90:2525-2535(2009).
CC   -!- FUNCTION: RNA-dependent RNA polymerase which replicates the viral
CC       genome. {ECO:0000305}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC         RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC         COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC         EC=2.7.7.48;
CC   -!- SIMILARITY: Belongs to the ssRNA positive-strand viruses RNA-directed
CC       RNA polymerase family. {ECO:0000305}.
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DR   EMBL; EU770623; ACF16360.1; -; mRNA.
DR   RefSeq; YP_002019757.1; NC_011068.1.
DR   GeneID; 8658756; -.
DR   KEGG; vg:8658756; -.
DR   Proteomes; UP000001103; Genome.
DR   GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR   GO; GO:0003968; F:RNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-KW.
DR   InterPro; IPR043502; DNA/RNA_pol_sf.
DR   SUPFAM; SSF56672; SSF56672; 1.
PE   2: Evidence at transcript level;
KW   Nucleotide-binding; Nucleotidyltransferase; Reference proteome;
KW   RNA-directed RNA polymerase; Transferase; Viral RNA replication.
FT   CHAIN           1..860
FT                   /note="RNA-dependent RNA polymerase"
FT                   /id="PRO_0000402474"
FT   REGION          839..860
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        840..860
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   860 AA;  97547 MW;  1FD0BEC36F566763 CRC64;
     MEPRQELLDP ERVREEAKRI VRWLCGLVDR TGKLPAGDYQ GKILNTVSEI CKRSKLPCGE
     LAEALTKGRL TRSLVDYSEL LISNLVVGYF DVLEIYLGKQ SVRLSDIREM ACKYTFYAIN
     RRLEDYIKFQ TAWLQARAMR DVTPEPEAPS WLNEGFGRCF SALLNRKVHL RCVLRARPND
     VSLAASLYQV KRVAPPLPDD QIEKNLEKSL DRLTKDEEPA GVDEPFLEDL KRECKRTVDE
     LVQNARREGW NRKISRDCFP SQSAAFENPI SKGGQLGQLV KENNTPRLPV LLGMFEYKGR
     VTPVYGWADD GDTILSDEEL GREVPAALKC RRSPVLEPFK VRVITMGPAV QYYRARRVQG
     CLWDLLKHTR CTHLPNRPVE ESDIGFYVRR RGADLFRGEE VPYVSGDYSA ATDNLHPDLS
     LSVVDRVCDH LLSDDNRPLD PVSPWRVLFH RVLVGHRIYD GNSSRNTEVA AQSWGQLMGS
     PLSFPVLCIV NLAVTRYVLE KACGRIVTLE ESGILVNGDD ILFRCPERTI PFWTRMVTIA
     GLSPSPGKNF VSYRYCQLNS ELYDMSGSRA EYLPFIKANL IYGTLARGCE RKRAADLCYG
     DTTTEGGTFG HRARALIKGF GPDMQDRLMS RFLHSIKGFL EKIPEVSWFI HPRYGGLGLP
     LTRPVTHNPY HLRIAAYLSC GGEQSQEARC MMQWLSAPTK SFNAATLLRI LEVARNCKVP
     FRKVPFALLH RAEAAGVDLE ALFRKALLRS APRLGVEYPS NESGDMQRLG DWRRFFRDVG
     RKAARTRCRS GTADERKGLF LMSPDNAVKG PQYEYIFDWA SHNMGGNIWD PSYKFRADPF
     SSSESDEPRA KEIGPNRGPE