ID   RDRP_WCCVB              Reviewed;         616 AA.
AC   Q64FP0;
DT   11-JAN-2011, integrated into UniProtKB/Swiss-Prot.
DT   25-OCT-2004, sequence version 1.
DT   29-SEP-2021, entry version 46.
DE   RecName: Full=RNA-directed RNA polymerase;
DE            EC=2.7.7.48;
OS   White clover cryptic virus 1 (isolate Boccardo/2004) (WCCV-1).
OC   Viruses; Riboviria; Orthornavirae; Pisuviricota; Duplopiviricetes;
OC   Durnavirales; Partitiviridae; Alphapartitivirus.
OX   NCBI_TaxID=654934;
OH   NCBI_TaxID=3899; Trifolium repens (Creeping white clover).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=15503214; DOI=10.1007/s00705-004-0422-8;
RA   Boccardo G., Candresse T.;
RT   "Complete sequence of the RNA1 of an isolate of White clover cryptic virus
RT   1, type species of the genus Alphacryptovirus.";
RL   Arch. Virol. 150:399-402(2005).
CC   -!- FUNCTION: RNA-dependent RNA polymerase which replicates the viral
CC       genome. {ECO:0000305}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC         RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC         COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC         EC=2.7.7.48;
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DR   EMBL; AY705784; AAU14888.1; -; Genomic_RNA.
DR   RefSeq; YP_086754.1; NC_006275.1.
DR   PRIDE; Q64FP0; -.
DR   GeneID; 5076437; -.
DR   KEGG; vg:5076437; -.
DR   Proteomes; UP000001672; Genome.
DR   GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0003968; F:RNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:InterPro.
DR   InterPro; IPR043502; DNA/RNA_pol_sf.
DR   InterPro; IPR001205; RNA-dir_pol_C.
DR   Pfam; PF00680; RdRP_1; 1.
DR   SUPFAM; SSF56672; SSF56672; 1.
PE   4: Predicted;
KW   Nucleotide-binding; Nucleotidyltransferase; Reference proteome;
KW   RNA-directed RNA polymerase; Transferase; Viral RNA replication.
FT   CHAIN           1..616
FT                   /note="RNA-directed RNA polymerase"
FT                   /id="PRO_0000402794"
SQ   SEQUENCE   616 AA;  72865 MW;  444D0D72112E037F CRC64;
     MDYLITAFNR ITHWFLTPTN LEYIGSYSLP PGLLRVNDVA VANHKATLDR SFDKYLYEHE
     INLITKEYRR SPIDEDSILE DFFSGDLPYF EIPFDEHVER GLECMAAAFR PPRPCRPAHI
     LDVKHGYPYK WNVNAEPPFS TDEYFLSQRK TFGEFIRMHE YEHIDKEDFF RRHPNIESHD
     FLRTVVPPKF GFLKSMIFSW TRRWHHIIKS GFQDSTDLEQ TGYFFNRFIF PMLLHTKTAI
     VKKNDPNKMR TIWGASKPWI IAETMFYWEY LAWIKHNPGA TPMLWGYETF TGGWFRLNHE
     LFCGLIQRSF LTLDWSRFDK RAYFPLLRRI LYTVKTFLTF EEGYVPTHAA PTHPQWSQEN
     IDRLERLWLW TLENLFEAPI ILPDGRMYRR HFAGIPSGLF ITQLLDSWYN YTMLATILSA
     LHFDPLHCII KVQGDDSILR LTTLIPVDQH TNFMDHIVRL ADTYFNSIVN VKKSEVRNSL
     NGCEVLSYRN HNGLPHRDEI TMLAQFYHTK ARDPTPEITM AQAIGFAYAS CANHNRVLWV
     LEDVYNYYRD LGYRPNRAGL TLTFGDSPDL TMPEMPLDHF PTKSEIRRYH TETHYQNEAQ
     NARTWPRTLF INAPGE