RDS1_XENLA
ID RDS1_XENLA Reviewed; 345 AA.
AC O42581;
DT 15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT 01-JAN-1998, sequence version 1.
DT 03-AUG-2022, entry version 87.
DE RecName: Full=RDS/peripherin-like protein xRDS35;
GN Name=rds35;
OS Xenopus laevis (African clawed frog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX NCBI_TaxID=8355;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RX PubMed=8923216; DOI=10.1242/jcs.109.10.2551;
RA Kedzierski W., Moghrabi W.N., Allen A.C., Jablonski-Stiemke M.M.,
RA Azarian S.M., Bok D., Travis G.H.;
RT "Three homologs of rds/peripherin in Xenopus laevis photoreceptors that
RT exhibit covalent and non-covalent interactions.";
RL J. Cell Sci. 109:2551-2560(1996).
CC -!- SUBUNIT: Homodimer; disulfide-linked.
CC -!- SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
CC -!- TISSUE SPECIFICITY: Rod specific.
CC -!- SIMILARITY: Belongs to the PRPH2/ROM1 family. {ECO:0000305}.
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DR EMBL; L79913; AAB64231.1; -; mRNA.
DR RefSeq; XP_018111940.1; XM_018256451.1.
DR AlphaFoldDB; O42581; -.
DR DNASU; 379513; -.
DR GeneID; 379513; -.
DR CTD; 379513; -.
DR Xenbase; XB-GENE-962407; rom1.L.
DR OMA; NDIHIVP; -.
DR OrthoDB; 1470436at2759; -.
DR Proteomes; UP000186698; Genome assembly.
DR Bgee; 379513; Expressed in camera-type eye and 8 other tissues.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0007601; P:visual perception; IEA:InterPro.
DR CDD; cd03162; peripherin_like_LEL; 1.
DR Gene3D; 1.10.1450.10; -; 1.
DR InterPro; IPR000830; Peripherin/rom-1.
DR InterPro; IPR018498; Peripherin/rom-1_CS.
DR InterPro; IPR042026; Peripherin_LEL.
DR InterPro; IPR018499; Tetraspanin/Peripherin.
DR InterPro; IPR008952; Tetraspanin_EC2_sf.
DR PANTHER; PTHR19282; PTHR19282; 1.
DR Pfam; PF00335; Tetraspanin; 1.
DR PRINTS; PR00218; PERIPHERNRDS.
DR SUPFAM; SSF48652; SSF48652; 1.
DR PROSITE; PS00930; RDS_ROM1; 1.
PE 2: Evidence at transcript level;
KW Disulfide bond; Glycoprotein; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..345
FT /note="RDS/peripherin-like protein xRDS35"
FT /id="PRO_0000168114"
FT TOPO_DOM 1..24
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 25..43
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 44..61
FT /note="Lumenal"
FT /evidence="ECO:0000255"
FT TRANSMEM 62..80
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 81..99
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 100..123
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 124..264
FT /note="Lumenal"
FT /evidence="ECO:0000255"
FT TRANSMEM 265..290
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 291..345
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT CARBOHYD 54
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 229
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 345 AA; 38719 MW; 100AFFECD20B3C8E CRC64;
MVLFKAKFSF QRRVKLAQTL WLLSWLSVLV GCLTFGMGIF LKVQLWIHNE VMENTSAHAV
PNTVITAGLV GILLGIYAGK VSQASMDVTK YQRWKSFMMP FFFLAILSCL VCLAALVLSV
ALRGTLEESL KIGLKNAIRF YKDTDTPGRC YQKRSMDKLQ MDFQCCGNNH PKDWFEVQWI
SNRYLDFSSK EVKDRIKSNV DGRYLMDSVP FSCCNPSSPR PCIQMQITNN SAHYSYNYQS
DELNIWVRGC REALLSYYTG IMATNGAAVT LSFLLQASVL VSLRYLHTSM DKISGPDDME
ADTEGFILEK GVTETMNTTL EKMKGLFMSN QVETAEGGGE AAAAS
