RDS2_CHICK
ID RDS2_CHICK Reviewed; 364 AA.
AC O42282;
DT 15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT 01-JAN-1998, sequence version 1.
DT 03-AUG-2022, entry version 106.
DE RecName: Full=Photoreceptor outer segment membrane glycoprotein 2;
DE AltName: Full=CRDS2;
OS Gallus gallus (Chicken).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC Phasianinae; Gallus.
OX NCBI_TaxID=9031;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC TISSUE=Retina;
RX PubMed=9478005;
RA Weng J., Belecky-Adams T., Adler R., Travis G.H.;
RT "Identification of two rds/peripherin homologs in the chick retina.";
RL Invest. Ophthalmol. Vis. Sci. 39:440-443(1998).
CC -!- SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
CC -!- SIMILARITY: Belongs to the PRPH2/ROM1 family. {ECO:0000305}.
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DR EMBL; AF031239; AAC06275.1; -; mRNA.
DR RefSeq; NP_990368.1; NM_205037.1.
DR AlphaFoldDB; O42282; -.
DR STRING; 9031.ENSGALP00000014944; -.
DR PaxDb; O42282; -.
DR PRIDE; O42282; -.
DR GeneID; 395898; -.
DR KEGG; gga:395898; -.
DR CTD; 100489375; -.
DR VEuPathDB; HostDB:geneid_395898; -.
DR eggNOG; KOG3882; Eukaryota.
DR OrthoDB; 1470436at2759; -.
DR PhylomeDB; O42282; -.
DR PRO; PR:O42282; -.
DR Proteomes; UP000000539; Unplaced.
DR GO; GO:0005887; C:integral component of plasma membrane; IBA:GO_Central.
DR GO; GO:0007601; P:visual perception; IEA:InterPro.
DR CDD; cd03162; peripherin_like_LEL; 1.
DR Gene3D; 1.10.1450.10; -; 1.
DR InterPro; IPR000830; Peripherin/rom-1.
DR InterPro; IPR018498; Peripherin/rom-1_CS.
DR InterPro; IPR042026; Peripherin_LEL.
DR InterPro; IPR018499; Tetraspanin/Peripherin.
DR InterPro; IPR008952; Tetraspanin_EC2_sf.
DR PANTHER; PTHR19282; PTHR19282; 1.
DR Pfam; PF00335; Tetraspanin; 1.
DR PRINTS; PR00218; PERIPHERNRDS.
DR SUPFAM; SSF48652; SSF48652; 1.
DR PROSITE; PS00930; RDS_ROM1; 1.
PE 2: Evidence at transcript level;
KW Glycoprotein; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..364
FT /note="Photoreceptor outer segment membrane glycoprotein 2"
FT /id="PRO_0000168116"
FT TOPO_DOM 1..24
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 25..43
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 44..61
FT /note="Lumenal"
FT /evidence="ECO:0000255"
FT TRANSMEM 62..80
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 81..99
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 100..123
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 124..264
FT /note="Lumenal"
FT /evidence="ECO:0000255"
FT TRANSMEM 265..290
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 291..364
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT CARBOHYD 229
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 364 AA; 41181 MW; 103DF550D4573EB3 CRC64;
MTVLKVKFTK TKRDKLAQIL WILNWVSVVS GIILFSLGLF LKIEIKKRNE VMAKGDINSV
PNMLISVGVI ACVVNFLGGK ICYDCSDANK FSRWKLIMLP YIICTFCFTF CILLGALMCY
TMRNELEESL YLGLRDAIKF YKDTDIPGRC FLKKTVDMLQ IGFQCCGNNG FRDWFEVQWV
SARYLNMASK EVMDRFKSNV DGKFLVDGVP FSCCNPSSPR PCIQYHLTNN SAHYNYDFLT
EELNIWVKGC REALLEYYTA IMRSIGIAAL LIWLFELSVL IGVRYLQTAM KNVLLQGDLQ
GESDGWLLEN SFVETAKYNI NIIKNLGKAN QISTVSGMND PNINVQNTNC GKSNVTAKSI
PAAS
