ID   RDS2_XENLA              Reviewed;         345 AA.
AC   O42582;
DT   15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   03-AUG-2022, entry version 91.
DE   RecName: Full=RDS/peripherin-like protein xRDS36;
GN   Name=rds36;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=8923216; DOI=10.1242/jcs.109.10.2551;
RA   Kedzierski W., Moghrabi W.N., Allen A.C., Jablonski-Stiemke M.M.,
RA   Azarian S.M., Bok D., Travis G.H.;
RT   "Three homologs of rds/peripherin in Xenopus laevis photoreceptors that
RT   exhibit covalent and non-covalent interactions.";
RL   J. Cell Sci. 109:2551-2560(1996).
CC   -!- SUBUNIT: Homodimer; disulfide-linked.
CC   -!- SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
CC   -!- TISSUE SPECIFICITY: Rod specific.
CC   -!- SIMILARITY: Belongs to the PRPH2/ROM1 family. {ECO:0000305}.
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DR   EMBL; L79914; AAB64232.1; -; mRNA.
DR   RefSeq; NP_001081693.1; NM_001088224.1.
DR   AlphaFoldDB; O42582; -.
DR   PRIDE; O42582; -.
DR   GeneID; 398001; -.
DR   KEGG; xla:398001; -.
DR   CTD; 398001; -.
DR   Xenbase; XB-GENE-17334124; rom1.S.
DR   OrthoDB; 1470436at2759; -.
DR   Proteomes; UP000186698; Chromosome 4S.
DR   Bgee; 398001; Expressed in camera-type eye and 3 other tissues.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0007601; P:visual perception; IEA:InterPro.
DR   CDD; cd03162; peripherin_like_LEL; 1.
DR   Gene3D; 1.10.1450.10; -; 1.
DR   InterPro; IPR000830; Peripherin/rom-1.
DR   InterPro; IPR018498; Peripherin/rom-1_CS.
DR   InterPro; IPR042026; Peripherin_LEL.
DR   InterPro; IPR018499; Tetraspanin/Peripherin.
DR   InterPro; IPR008952; Tetraspanin_EC2_sf.
DR   PANTHER; PTHR19282; PTHR19282; 1.
DR   Pfam; PF00335; Tetraspanin; 1.
DR   PRINTS; PR00218; PERIPHERNRDS.
DR   SUPFAM; SSF48652; SSF48652; 1.
DR   PROSITE; PS00930; RDS_ROM1; 1.
PE   2: Evidence at transcript level;
KW   Disulfide bond; Glycoprotein; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..345
FT                   /note="RDS/peripherin-like protein xRDS36"
FT                   /id="PRO_0000168115"
FT   TOPO_DOM        1..24
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        25..43
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        44..61
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        62..80
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        81..99
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        100..123
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        124..264
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        265..290
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        291..345
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        54
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        229
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   345 AA;  38727 MW;  DF8F0BC2FB8DF778 CRC64;
     MVLFKAKFSF QRRVKLAQTL WLLSWLSVLV GCLTFGMGIF LKVQLWIHNE VMDNTTAHAV
     PNTVITAGLV GILLGYFAGK ISQASMDLTK YQRWKSFMMP FFFLAILSCI VCLAALVLSV
     ALRGTLEESL KIGLRNAIRF YKDTDTPGRC YQKRSMDKLE MDFQCCGNNH PKDWFEVQWI
     SNRYLDFSSK EVKDRIKSSV DGRYLMDSVP FTCCNPSSPR PCIQIEITNN SAHYSYNFQG
     DDVNIWVRGC REALLGYYTG IMATNGAAVT LSFLLQASVL VSLRYVQTSM DKIRDPDDVE
     ADTEGFLLEK GVMETVNSSL EKIKDLFKSN QVETAEGGGE GAAGS