RDXB_CERS4
ID RDXB_CERS4 Reviewed; 477 AA.
AC P54932; P72341; Q3J016;
DT 01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT 19-SEP-2003, sequence version 2.
DT 03-AUG-2022, entry version 121.
DE RecName: Full=Protein RdxB;
GN Name=rdxB; OrderedLocusNames=RHOS4_23000; ORFNames=RSP_0692;
OS Cereibacter sphaeroides (strain ATCC 17023 / DSM 158 / JCM 6121 / CCUG
OS 31486 / LMG 2827 / NBRC 12203 / NCIMB 8253 / ATH 2.4.1.) (Rhodobacter
OS sphaeroides).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Rhodobacterales;
OC Rhodobacteraceae; Cereibacter.
OX NCBI_TaxID=272943;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND FUNCTION.
RX PubMed=9068641; DOI=10.1128/jb.179.6.1951-1961.1997;
RA O'Gara J.P., Kaplan S.;
RT "Evidence for the role of redox carriers in photosynthesis gene expression
RT and carotenoid biosynthesis in Rhodobacter sphaeroides 2.4.1.";
RL J. Bacteriol. 179:1951-1961(1997).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 17023 / DSM 158 / JCM 6121 / CCUG 31486 / LMG 2827 / NBRC 12203
RC / NCIMB 8253 / ATH 2.4.1.;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA Hammon N., Israni S., Pitluck S., Richardson P., Mackenzie C.,
RA Choudhary M., Larimer F., Hauser L.J., Land M., Donohue T.J., Kaplan S.;
RT "Complete sequence of chromosome 1 of Rhodobacter sphaeroides 2.4.1.";
RL Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-184.
RX PubMed=7592416; DOI=10.1128/jb.177.22.6422-6431.1995;
RA Zeilstra-Ryalls J.H., Kaplan S.;
RT "Aerobic and anaerobic regulation in Rhodobacter sphaeroides 2.4.1: the
RT role of the fnrL gene.";
RL J. Bacteriol. 177:6422-6431(1995).
CC -!- FUNCTION: Involved in a membrane generated redox signal; required to
CC maintain repression of photosynthesis gene expression in the presence
CC of oxygen. {ECO:0000269|PubMed:9068641}.
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Note=Binds 2 [4Fe-4S] clusters per subunit.;
CC -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
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DR EMBL; AF202779; AAF44623.1; -; Genomic_DNA.
DR EMBL; CP000143; ABA79868.1; -; Genomic_DNA.
DR RefSeq; WP_011338421.1; NZ_CP030271.1.
DR RefSeq; YP_353769.1; NC_007493.2.
DR AlphaFoldDB; P54932; -.
DR SMR; P54932; -.
DR STRING; 272943.RSP_0692; -.
DR EnsemblBacteria; ABA79868; ABA79868; RSP_0692.
DR KEGG; rsp:RSP_0692; -.
DR PATRIC; fig|272943.9.peg.2644; -.
DR eggNOG; COG0348; Bacteria.
DR OMA; EMVFRRI; -.
DR PhylomeDB; P54932; -.
DR Proteomes; UP000002703; Chromosome 1.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 2.60.40.10; -; 1.
DR InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR InterPro; IPR017900; 4Fe4S_Fe_S_CS.
DR InterPro; IPR014116; Cyt_c_oxidase_cbb3_FixG.
DR InterPro; IPR032879; FixG_C.
DR InterPro; IPR013783; Ig-like_fold.
DR Pfam; PF13746; Fer4_18; 1.
DR Pfam; PF12801; Fer4_5; 1.
DR Pfam; PF11614; FixG_C; 1.
DR TIGRFAMs; TIGR02745; ccoG_rdxA_fixG; 1.
DR PROSITE; PS00198; 4FE4S_FER_1; 1.
DR PROSITE; PS51379; 4FE4S_FER_2; 1.
PE 4: Predicted;
KW 4Fe-4S; Cell membrane; Electron transport; Iron; Iron-sulfur; Membrane;
KW Metal-binding; Reference proteome; Transmembrane; Transmembrane helix;
KW Transport.
FT CHAIN 1..477
FT /note="Protein RdxB"
FT /id="PRO_0000159238"
FT TOPO_DOM 1..29
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 30..50
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 51..81
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 82..102
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 103..154
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 155..175
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 176..189
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 190..210
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 211..338
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 339..359
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 360..477
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT DOMAIN 253..281
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00711"
FT BINDING 262
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="1"
FT /evidence="ECO:0000250"
FT BINDING 265
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="1"
FT /evidence="ECO:0000250"
FT BINDING 268
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="1"
FT /evidence="ECO:0000250"
FT BINDING 272
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="2"
FT /evidence="ECO:0000250"
FT BINDING 286
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="2"
FT /evidence="ECO:0000250"
FT BINDING 289
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="2"
FT /evidence="ECO:0000250"
FT BINDING 292
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="2"
FT /evidence="ECO:0000250"
FT BINDING 296
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="1"
FT /evidence="ECO:0000250"
SQ SEQUENCE 477 AA; 53947 MW; 0D2E817FBDD6F5FF CRC64;
MTSPDTQTSS LYAKREPVFP KRVSGKFRSL KWWIMGVTLG IYYIAPWLRW DRGPNLPDQA
ILVDLANRRF FFFMIEIWPH EFYFVAGLLI MAGLGLFLFT SAAGRVWCGY ACPQTVWTDL
FILVERWVEG DRNARIRLLR QRWDLEKTRK YLTKWTLWLL IGLATGGAWV FYFTDAPTLL
VDLLTGNAHP VAYITMATLT ATTFAFGGFA REQICIYACP WPRIQAAMMD EETITVAYRE
WRGEPRGKLK KGEPLSPDQG DCIDCMACVN VCPMGIDIRD GQQLACITCA LCIDACDEVM
DKIGKPRGLI GYLALTDERA EREGRSPRSA WRHVFRLRTL IYTALWSGVG LALIVALFLR
SPIDINVTPL RNPLYVTLSD GSIRNTYDVR LRNKQGEARD YQISVTSEAD LALSLEGHPA
TVVTVPANET MTQRVYIIAG KGTPAAEAER TDLRLWVEDL AAGQRVHHDT IFNGRGN
