ID   RE104_SACPS             Reviewed;         185 AA.
AC   Q92379;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1997, sequence version 1.
DT   25-MAY-2022, entry version 47.
DE   RecName: Full=Meiotic recombination protein REC104;
GN   Name=REC104;
OS   Saccharomyces pastorianus (Lager yeast) (Saccharomyces cerevisiae x
OS   Saccharomyces eubayanus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=27292;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=DBVPG 6258 / CBS 1486;
RX   PubMed=9000375; DOI=10.1007/s002940050170;
RA   Nau J.J., Summers K.R., Galbraith A.M., Bullard S.A., Malone R.E.;
RT   "Isolation of early meiotic recombination genes analogous to S. cerevisiae
RT   REC104 from the yeasts S. paradoxus and S. pastorianus.";
RL   Curr. Genet. 31:7-14(1997).
CC   -!- FUNCTION: Potential transcriptional regulator that is required to
CC       activate expression of a number of early meiotic genes including HOP1.
CC       {ECO:0000250}.
CC   -!- DEVELOPMENTAL STAGE: Meiosis-specific.
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DR   EMBL; U66720; AAB41529.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q92379; -.
DR   GO; GO:0042138; P:meiotic DNA double-strand break formation; IEA:InterPro.
DR   InterPro; IPR035349; Rec104.
DR   Pfam; PF17378; REC104; 1.
PE   2: Evidence at transcript level;
KW   Activator; Meiosis; Transcription; Transcription regulation.
FT   CHAIN           1..185
FT                   /note="Meiotic recombination protein REC104"
FT                   /id="PRO_0000097215"
FT   REGION          146..168
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   185 AA;  21014 MW;  E747A63B17C6D817 CRC64;
     MSTNKEEEHQ IVCTQDFLRQ YYVSESVSIQ FGLNNKTIRT INEEEFNNAA MCIMTRTNYP
     ESTLKRSAST YLLNSYHKKP ATLSLPFVFG DTINLSEDME DNNENNLLYS DTLYGDDSLT
     QRGDQVVYKI DTQEEDSSFT LLQSEANETR PLSSSSTPQI LQSDYSVVMQ EGQTSNGSIF
     QFSSP