ID   REC16_SCHPO             Reviewed;         472 AA.
AC   P40379;
DT   01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1995, sequence version 1.
DT   25-MAY-2022, entry version 135.
DE   RecName: Full=Transcriptional activator protein rec16;
DE   AltName: Full=Zinc finger protein rep1;
GN   Name=rec16; Synonyms=rep1; ORFNames=SPBC2D10.06;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=8168486; DOI=10.1002/j.1460-2075.1994.tb06457.x;
RA   Sugiyama A., Tanaka K., Okazaki K., Nojima H., Okayama H.;
RT   "A zinc finger protein controls the onset of premeiotic DNA synthesis of
RT   fission yeast in a Mei2-independent cascade.";
RL   EMBO J. 13:1881-1887(1994).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], FUNCTION, AND GENE NAME.
RX   PubMed=9671035; DOI=10.1007/s004380050780;
RA   Ding R., Smith G.R.;
RT   "Global control of meiotic recombination genes by Schizosaccharomyces pombe
RT   rec16 (rep1).";
RL   Mol. Gen. Genet. 258:663-670(1998).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
CC   -!- FUNCTION: Transcriptional activator that controls the onset of
CC       premeiotic DNA synthesis by regulating res2 and some other factor(s) in
CC       a mei2 independent cascade. {ECO:0000269|PubMed:9671035}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; X77518; CAA54653.1; -; Genomic_DNA.
DR   EMBL; CU329671; CAA21164.1; -; Genomic_DNA.
DR   PIR; T45219; T45219.
DR   RefSeq; NP_596225.1; NM_001022145.2.
DR   AlphaFoldDB; P40379; -.
DR   SMR; P40379; -.
DR   BioGRID; 276961; 17.
DR   STRING; 4896.SPBC2D10.06.1; -.
DR   PaxDb; P40379; -.
DR   EnsemblFungi; SPBC2D10.06.1; SPBC2D10.06.1:pep; SPBC2D10.06.
DR   GeneID; 2540433; -.
DR   KEGG; spo:SPBC2D10.06; -.
DR   PomBase; SPBC2D10.06; -.
DR   VEuPathDB; FungiDB:SPBC2D10.06; -.
DR   HOGENOM; CLU_615621_0_0_1; -.
DR   OMA; MQRSATW; -.
DR   PRO; PR:P40379; -.
DR   Proteomes; UP000002485; Chromosome II.
DR   GO; GO:0005634; C:nucleus; HDA:PomBase.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003713; F:transcription coactivator activity; IMP:PomBase.
DR   GO; GO:0010672; P:regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle; IMP:PomBase.
DR   InterPro; IPR013087; Znf_C2H2_type.
DR   PROSITE; PS00028; ZINC_FINGER_C2H2_1; 1.
PE   4: Predicted;
KW   Activator; DNA-binding; Metal-binding; Nucleus; Reference proteome;
KW   Transcription; Transcription regulation; Zinc; Zinc-finger.
FT   CHAIN           1..472
FT                   /note="Transcriptional activator protein rec16"
FT                   /id="PRO_0000046816"
FT   ZN_FING         420..444
FT                   /note="C2H2-type"
SQ   SEQUENCE   472 AA;  52618 MW;  CDEF1C9DA60136BF CRC64;
     MDSDRCLTDE ISLNTLSSTF ASDNNLRRKE NFLKSRYPSK FDLNVSMLTK SDDVGKTPFS
     IFDSPSNPGF SRSHQMCSDK NKSPFLFDKI RDEPVSVDPV KLIINNRNKR KINRQKSRLQ
     GLYRSDANGL QPLNSENVKM KKSTALSLTS SPLNSWKTDF KTPPKANVVC ISLVIEGDGC
     ASLLYEDLNQ ISNSCPEVAP NRQNALFSDE TLTTMFYSGV TEDEGSCNNL LQSSFGDDLD
     LGMQRSATWA PGYNYPSKFD SIPFASASPK IKAAFPFDPN VYALNTNDGP VTSTDNNCDQ
     LNTRMQAWNN GFNYSNLNGD IQYPAVTPKF FQQEGRALNV SDCNFGNEEI AYGGIPMRVC
     HSDSTLCDAR IAAKQALKGK RQYDTSTSKA ELSTPPSKRR HIDDADLVFH SSPLLSRSRF
     ICCYCTKPFL SISKLQEHES SCSHVERLFG FAPNRLYDDG DGFLGSSFCS DW