ID   REC24_SCHPO             Reviewed;         350 AA.
AC   Q9UUJ4;
DT   11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   25-MAY-2022, entry version 80.
DE   RecName: Full=Meiotic recombination protein rec24;
DE   AltName: Full=Meiotically up-regulated gene 6 protein;
GN   Name=rec24; Synonyms=mug6; ORFNames=SPAC1952.15c;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2]
RP   FUNCTION IN MEIOSIS.
RX   PubMed=16303567; DOI=10.1016/j.cub.2005.10.038;
RA   Martin-Castellanos C., Blanco M., Rozalen A.E., Perez-Hidalgo L.,
RA   Garcia A.I., Conde F., Mata J., Ellermeier C., Davis L., San-Segundo P.,
RA   Smith G.R., Moreno S.;
RT   "A large-scale screen in S. pombe identifies seven novel genes required for
RT   critical meiotic events.";
RL   Curr. Biol. 15:2056-2062(2005).
RN   [3]
RP   SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX   PubMed=16823372; DOI=10.1038/nbt1222;
RA   Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA   Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA   Yoshida M.;
RT   "ORFeome cloning and global analysis of protein localization in the fission
RT   yeast Schizosaccharomyces pombe.";
RL   Nat. Biotechnol. 24:841-847(2006).
CC   -!- FUNCTION: Required for correct meiotic chromosome segregation and
CC       recombination. {ECO:0000269|PubMed:16303567}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus
CC       {ECO:0000269|PubMed:16823372}.
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DR   EMBL; CU329670; CAB52579.1; -; Genomic_DNA.
DR   PIR; T37943; T37943.
DR   RefSeq; NP_594817.1; NM_001020246.2.
DR   AlphaFoldDB; Q9UUJ4; -.
DR   BioGRID; 279072; 12.
DR   STRING; 4896.SPAC1952.15c.1; -.
DR   PaxDb; Q9UUJ4; -.
DR   EnsemblFungi; SPAC1952.15c.1; SPAC1952.15c.1:pep; SPAC1952.15c.
DR   GeneID; 2542618; -.
DR   KEGG; spo:SPAC1952.15c; -.
DR   PomBase; SPAC1952.15c; rec24.
DR   VEuPathDB; FungiDB:SPAC1952.15c; -.
DR   HOGENOM; CLU_826819_0_0_1; -.
DR   OMA; DTHRIMQ; -.
DR   PRO; PR:Q9UUJ4; -.
DR   Proteomes; UP000002485; Chromosome I.
DR   GO; GO:0005829; C:cytosol; HDA:PomBase.
DR   GO; GO:0030998; C:linear element; IDA:PomBase.
DR   GO; GO:0005634; C:nucleus; HDA:PomBase.
DR   GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.
DR   GO; GO:0042138; P:meiotic DNA double-strand break formation; IEA:InterPro.
DR   GO; GO:0007131; P:reciprocal meiotic recombination; IMP:PomBase.
DR   InterPro; IPR025888; MEI4.
DR   Pfam; PF13971; Mei4; 1.
PE   1: Evidence at protein level;
KW   Chromosome partition; Cytoplasm; Meiosis; Nucleus; Reference proteome.
FT   CHAIN           1..350
FT                   /note="Meiotic recombination protein rec24"
FT                   /id="PRO_0000300499"
SQ   SEQUENCE   350 AA;  40259 MW;  D77FF4C190FAD576 CRC64;
     MNGTNTEDNS KQILIQTMYT YDSSGETLKI AIAWKIILKK PKGKNIKDYI EALRKGIEDQ
     EHCEKYASTL LEPRPKTKKD VVLKNSNVTE CVALKAKPFS KKIEDMDIFL LTNVHENLQE
     KRQTSGSLAH LDIEYTFNGL FRFLKCTADI KLKQTKVYEG ADFLRIKTLF EEIFMFLKRD
     CKSPLVLTRL VELGDYVLDL IIITQSIMQN NANNGTGVIS RAKFLEFYVF LEQLIFNKLS
     FASVEQLEKL LDQIVKRMKI CFTYCKNDNP SIRLLYSECF FSYAEIYFPC LHSFDAQLSS
     AASKCVQILR DIITNEELQT DKQELSKSAY SAPSILLIGL KDMLFPEDIS