RECA1_MYXXA
ID RECA1_MYXXA Reviewed; 342 AA.
AC P48291;
DT 01-FEB-1996, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1996, sequence version 1.
DT 03-AUG-2022, entry version 99.
DE RecName: Full=Protein RecA 1 {ECO:0000255|HAMAP-Rule:MF_00268};
DE AltName: Full=Recombinase A 1 {ECO:0000255|HAMAP-Rule:MF_00268};
GN Name=recA1 {ECO:0000255|HAMAP-Rule:MF_00268};
OS Myxococcus xanthus.
OC Bacteria; Proteobacteria; Deltaproteobacteria; Myxococcales;
OC Cystobacterineae; Myxococcaceae; Myxococcus.
OX NCBI_TaxID=34;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=7608099; DOI=10.1128/jb.177.14.4179-4182.1995;
RA Norioka N., Hsu M.-Y., Inouye S., Inouye M.;
RT "Two recA genes in Myxococcus xanthus.";
RL J. Bacteriol. 177:4179-4182(1995).
CC -!- FUNCTION: Can catalyze the hydrolysis of ATP in the presence of single-
CC stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex
CC DNA, and the ATP-dependent hybridization of homologous single-stranded
CC DNAs. It interacts with LexA causing its activation and leading to its
CC autocatalytic cleavage. {ECO:0000255|HAMAP-Rule:MF_00268}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00268}.
CC -!- MISCELLANEOUS: There are two genes for RecA in M.xanthus; recA1 seems
CC less functional than recA2.
CC -!- SIMILARITY: Belongs to the RecA family. {ECO:0000255|HAMAP-
CC Rule:MF_00268}.
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DR EMBL; L40367; AAC37000.1; -; Genomic_DNA.
DR PIR; A57364; A57364.
DR RefSeq; WP_011551557.1; NZ_JABFNQ010000051.1.
DR AlphaFoldDB; P48291; -.
DR SMR; P48291; -.
DR PRIDE; P48291; -.
DR GeneID; 41358887; -.
DR OMA; EGARHMS; -.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0003684; F:damaged DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003697; F:single-stranded DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-UniRule.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-UniRule.
DR GO; GO:0009432; P:SOS response; IEA:UniProtKB-UniRule.
DR CDD; cd00983; recA; 1.
DR Gene3D; 3.40.50.300; -; 1.
DR HAMAP; MF_00268; RecA; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR013765; DNA_recomb/repair_RecA.
DR InterPro; IPR020584; DNA_recomb/repair_RecA_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR020588; RecA_ATP-bd.
DR InterPro; IPR023400; RecA_C.
DR InterPro; IPR020587; RecA_monomer-monomer_interface.
DR PANTHER; PTHR45900; PTHR45900; 1.
DR Pfam; PF00154; RecA; 1.
DR PRINTS; PR00142; RECA.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR SUPFAM; SSF54752; SSF54752; 1.
DR TIGRFAMs; TIGR02012; tigrfam_recA; 1.
DR PROSITE; PS00321; RECA_1; 1.
DR PROSITE; PS50162; RECA_2; 1.
DR PROSITE; PS50163; RECA_3; 1.
PE 3: Inferred from homology;
KW ATP-binding; Cytoplasm; DNA damage; DNA recombination; DNA repair;
KW DNA-binding; Nucleotide-binding; SOS response.
FT CHAIN 1..342
FT /note="Protein RecA 1"
FT /id="PRO_0000122768"
FT BINDING 68..75
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00268"
SQ SEQUENCE 342 AA; 36055 MW; 7F868E4F9F0B47E4 CRC64;
MSKLAEKLKA VAAAVASIEK QFGRGSVMTL GGEAREQKVA VIPSGSVGVD RALGVGGYPR
GRVVEVFGNE SSGKTTLTLH AIAQVQAAGG VAAFIDAEHA LDVSYARKLG VRVEELLVSQ
PDTGEQALEI TEHLVRSGAV DLIVVDSVAA LVPRAEIEGE MGDAHMGVQA RLMSQALRKL
TGAVSRSGTC IIFINQIRMK IGVMFGNPET TTGGNALKFY ASVRMEIRRT GNIKDGDAVV
GSKARVKVVK NKVAPPFQEA EFDLMYGSGI HRVGEVLDLG VATGLIEKSG SYFSLRGERI
GQGRERAAEW LREHPDVLEA LGKEITGTSA LPSSPAPVEV AA
