RECA2_MYXXA
ID RECA2_MYXXA Reviewed; 358 AA.
AC P48292;
DT 01-FEB-1996, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1996, sequence version 1.
DT 03-AUG-2022, entry version 94.
DE RecName: Full=Protein RecA 2 {ECO:0000255|HAMAP-Rule:MF_00268};
DE AltName: Full=Recombinase A 2 {ECO:0000255|HAMAP-Rule:MF_00268};
GN Name=recA2 {ECO:0000255|HAMAP-Rule:MF_00268};
OS Myxococcus xanthus.
OC Bacteria; Proteobacteria; Deltaproteobacteria; Myxococcales;
OC Cystobacterineae; Myxococcaceae; Myxococcus.
OX NCBI_TaxID=34;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=7608099; DOI=10.1128/jb.177.14.4179-4182.1995;
RA Norioka N., Hsu M.-Y., Inouye S., Inouye M.;
RT "Two recA genes in Myxococcus xanthus.";
RL J. Bacteriol. 177:4179-4182(1995).
CC -!- FUNCTION: Can catalyze the hydrolysis of ATP in the presence of single-
CC stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex
CC DNA, and the ATP-dependent hybridization of homologous single-stranded
CC DNAs. It interacts with LexA causing its activation and leading to its
CC autocatalytic cleavage. {ECO:0000255|HAMAP-Rule:MF_00268}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00268}.
CC -!- MISCELLANEOUS: There are two genes for RecA in M.xanthus; recA1 seems
CC less functional than recA2.
CC -!- SIMILARITY: Belongs to the RecA family. {ECO:0000255|HAMAP-
CC Rule:MF_00268}.
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DR EMBL; L40368; AAC37001.1; -; Genomic_DNA.
DR AlphaFoldDB; P48292; -.
DR SMR; P48292; -.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0003684; F:damaged DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003697; F:single-stranded DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-UniRule.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-UniRule.
DR GO; GO:0009432; P:SOS response; IEA:UniProtKB-UniRule.
DR CDD; cd00983; recA; 1.
DR Gene3D; 3.40.50.300; -; 1.
DR HAMAP; MF_00268; RecA; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR013765; DNA_recomb/repair_RecA.
DR InterPro; IPR020584; DNA_recomb/repair_RecA_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR020588; RecA_ATP-bd.
DR InterPro; IPR023400; RecA_C.
DR InterPro; IPR020587; RecA_monomer-monomer_interface.
DR PANTHER; PTHR45900; PTHR45900; 1.
DR Pfam; PF00154; RecA; 1.
DR PRINTS; PR00142; RECA.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR SUPFAM; SSF54752; SSF54752; 1.
DR TIGRFAMs; TIGR02012; tigrfam_recA; 1.
DR PROSITE; PS00321; RECA_1; 1.
DR PROSITE; PS50162; RECA_2; 1.
DR PROSITE; PS50163; RECA_3; 1.
PE 3: Inferred from homology;
KW ATP-binding; Cytoplasm; DNA damage; DNA recombination; DNA repair;
KW DNA-binding; Nucleotide-binding; SOS response.
FT CHAIN 1..358
FT /note="Protein RecA 2"
FT /id="PRO_0000122769"
FT REGION 331..358
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 69..76
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00268"
SQ SEQUENCE 358 AA; 38746 MW; 15BB97C22DB537D3 CRC64;
MAVNQEKEKA IELAMSAVER QFGKGSIMRL GNDEPMMRDV QAIPTGSISL DIALGVGGVP
KGRIIEIFGP ESSGKTTLCL HIVAEAQKRG GICGYVDAEH ALDVGYARKL GVRTDDLLLS
QPDTGEQALE IAEMLVRSGA IDVLVVDSVA ALVPKAELEG EMGDAHMGVQ ARLMSQALRK
LTGTIAKSQT CVIFINQIRM KIGVMFGNPE TTTGGNALKF YASQRLDIRR IGAIKNGDNV
VGSRTRVKVV KNKVAPPFKE VEFDIMYGTG ISREGDLIDL ASNENIVEKS GSWFSFNGER
IGQGRENVKE YLREHPEIAK DIEGRVLEKY GIGKSGAPSP RRRTSPRRPK VAARSAAV
