RECA_AERS4
ID RECA_AERS4 Reviewed; 353 AA.
AC P94190; A4SS97;
DT 15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT 29-MAY-2007, sequence version 2.
DT 03-AUG-2022, entry version 129.
DE RecName: Full=Protein RecA {ECO:0000255|HAMAP-Rule:MF_00268};
DE AltName: Full=Recombinase A {ECO:0000255|HAMAP-Rule:MF_00268};
GN Name=recA {ECO:0000255|HAMAP-Rule:MF_00268}; OrderedLocusNames=ASA_3809;
OS Aeromonas salmonicida (strain A449).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Aeromonadales;
OC Aeromonadaceae; Aeromonas.
OX NCBI_TaxID=382245;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=8917089; DOI=10.1016/0378-1119(96)00138-2;
RA Umelo E., Noonan B., Trust T.J.;
RT "Cloning, characterization and expression of the recA gene of Aeromonas
RT salmonicida.";
RL Gene 175:133-136(1996).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=A449;
RX PubMed=18801193; DOI=10.1186/1471-2164-9-427;
RA Reith M.E., Singh R.K., Curtis B., Boyd J.M., Bouevitch A., Kimball J.,
RA Munholland J., Murphy C., Sarty D., Williams J., Nash J.H., Johnson S.C.,
RA Brown L.L.;
RT "The genome of Aeromonas salmonicida subsp. salmonicida A449: insights into
RT the evolution of a fish pathogen.";
RL BMC Genomics 9:427-427(2008).
CC -!- FUNCTION: Can catalyze the hydrolysis of ATP in the presence of single-
CC stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex
CC DNA, and the ATP-dependent hybridization of homologous single-stranded
CC DNAs. It interacts with LexA causing its activation and leading to its
CC autocatalytic cleavage.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00268}.
CC -!- SIMILARITY: Belongs to the RecA family. {ECO:0000255|HAMAP-
CC Rule:MF_00268}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; U83688; AAB41053.1; -; Genomic_DNA.
DR EMBL; CP000644; ABO91769.1; -; Genomic_DNA.
DR PIR; JC5198; JC5198.
DR RefSeq; WP_005315774.1; NC_009348.1.
DR AlphaFoldDB; P94190; -.
DR SMR; P94190; -.
DR STRING; 382245.ASA_3809; -.
DR EnsemblBacteria; ABO91769; ABO91769; ASA_3809.
DR KEGG; asa:ASA_3809; -.
DR eggNOG; COG0468; Bacteria.
DR HOGENOM; CLU_040469_3_2_6; -.
DR OMA; DYGEQAL; -.
DR OrthoDB; 1080436at2; -.
DR Proteomes; UP000000225; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0003684; F:damaged DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003697; F:single-stranded DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-UniRule.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-UniRule.
DR GO; GO:0009432; P:SOS response; IEA:UniProtKB-UniRule.
DR CDD; cd00983; recA; 1.
DR Gene3D; 3.40.50.300; -; 1.
DR HAMAP; MF_00268; RecA; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR013765; DNA_recomb/repair_RecA.
DR InterPro; IPR020584; DNA_recomb/repair_RecA_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR020588; RecA_ATP-bd.
DR InterPro; IPR023400; RecA_C.
DR InterPro; IPR020587; RecA_monomer-monomer_interface.
DR PANTHER; PTHR45900; PTHR45900; 1.
DR Pfam; PF00154; RecA; 1.
DR PRINTS; PR00142; RECA.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR SUPFAM; SSF54752; SSF54752; 1.
DR TIGRFAMs; TIGR02012; tigrfam_recA; 1.
DR PROSITE; PS00321; RECA_1; 1.
DR PROSITE; PS50162; RECA_2; 1.
DR PROSITE; PS50163; RECA_3; 1.
PE 3: Inferred from homology;
KW ATP-binding; Cytoplasm; DNA damage; DNA recombination; DNA repair;
KW DNA-binding; Nucleotide-binding; SOS response.
FT CHAIN 1..353
FT /note="Protein RecA"
FT /id="PRO_0000122635"
FT BINDING 65..72
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00268"
FT CONFLICT 27
FT /note="R -> L (in Ref. 1; AAB41053)"
FT /evidence="ECO:0000305"
FT CONFLICT 118
FT /note="P -> S (in Ref. 1; AAB41053)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 353 AA; 37983 MW; F365A27232A7B2A9 CRC64;
MDQNKQKALA AALGQIEKQF GKGSIMRLGD SKTMDIEAIS TGSLSLDVAL GIGGLPCGRI
VEIYGPESSG KTTLTLQVIA EAQKKGKVCA FIDAEHALDP IYAAKLGVNV DDLLISQPDT
GEQALEICDM LVRSNAVDVI IVDSVAALTP KAEIEGEMGD SHVGLQARLM SQALRKLTAN
IKNANCLCIF INQIRMKIGV MFGSPETTTG GNALKFYASV RLDIRRIGAI KEGDEVVGNE
TRVKVVKNKV APPFKQAEFQ IFYGVGISKE GELVDLGVKH KLIDKAGAWY SYNGEKIGQG
KANVMKLFTE NKVMAAEVEA RLRELLLSGD VPAEKPVVAD ADELEAESEQ EFE
