ID   RECA_CAMLA              Reviewed;         344 AA.
AC   Q93R37; Q93R36;
DT   16-APR-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2001, sequence version 1.
DT   03-AUG-2022, entry version 89.
DE   RecName: Full=Protein RecA {ECO:0000255|HAMAP-Rule:MF_00268};
DE   AltName: Full=Recombinase A {ECO:0000255|HAMAP-Rule:MF_00268};
GN   Name=recA {ECO:0000255|HAMAP-Rule:MF_00268};
OS   Campylobacter lari.
OC   Bacteria; Proteobacteria; Epsilonproteobacteria; Campylobacterales;
OC   Campylobacteraceae; Campylobacter.
OX   NCBI_TaxID=201;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 35221 / DSM 11375 / JCM 2530 / LMG 8846 / NCTC 11352;
RA   Honda M., Matsushita S., Murayama O., Millar B.C., Moore J.E., Matsuda M.;
RT   "Cloning and sequence analysis of the recA gene of Campylobacter lari
RT   JCM2530.";
RL   Submitted (AUG-2001) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=NCTC 12894 / A692/85;
RA   Matsuda M., Honda M., Matsushita S., Matsui T., Murayama O., Millar B.C.,
RA   Moore J.E.;
RT   "Cloning and sequence analysis of the recA gene of urease-positive
RT   thermophilic Campylobacter.";
RL   Submitted (AUG-2001) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Can catalyze the hydrolysis of ATP in the presence of single-
CC       stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex
CC       DNA, and the ATP-dependent hybridization of homologous single-stranded
CC       DNAs. It interacts with LexA causing its activation and leading to its
CC       autocatalytic cleavage. {ECO:0000255|HAMAP-Rule:MF_00268}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00268}.
CC   -!- SIMILARITY: Belongs to the RecA family. {ECO:0000255|HAMAP-
CC       Rule:MF_00268}.
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DR   EMBL; AB067767; BAB62716.1; -; Genomic_DNA.
DR   EMBL; AB067768; BAB62717.1; -; Genomic_DNA.
DR   RefSeq; WP_039617275.1; NZ_UFVM01000002.1.
DR   AlphaFoldDB; Q93R37; -.
DR   SMR; Q93R37; -.
DR   OrthoDB; 1080436at2; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR   GO; GO:0003684; F:damaged DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003697; F:single-stranded DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-UniRule.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-UniRule.
DR   GO; GO:0009432; P:SOS response; IEA:UniProtKB-UniRule.
DR   CDD; cd00983; recA; 1.
DR   Gene3D; 3.40.50.300; -; 1.
DR   HAMAP; MF_00268; RecA; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR013765; DNA_recomb/repair_RecA.
DR   InterPro; IPR020584; DNA_recomb/repair_RecA_CS.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR020588; RecA_ATP-bd.
DR   InterPro; IPR023400; RecA_C.
DR   InterPro; IPR020587; RecA_monomer-monomer_interface.
DR   PANTHER; PTHR45900; PTHR45900; 1.
DR   Pfam; PF00154; RecA; 1.
DR   PRINTS; PR00142; RECA.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   SUPFAM; SSF54752; SSF54752; 1.
DR   TIGRFAMs; TIGR02012; tigrfam_recA; 1.
DR   PROSITE; PS00321; RECA_1; 1.
DR   PROSITE; PS50162; RECA_2; 1.
DR   PROSITE; PS50163; RECA_3; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cytoplasm; DNA damage; DNA recombination; DNA repair;
KW   DNA-binding; Nucleotide-binding; SOS response.
FT   CHAIN           1..344
FT                   /note="Protein RecA"
FT                   /id="PRO_0000122679"
FT   BINDING         65..72
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00268"
FT   VARIANT         101
FT                   /note="K -> R (in strain: NCTC 12894)"
FT   VARIANT         105
FT                   /note="D -> N (in strain: NCTC 12894)"
FT   VARIANT         176
FT                   /note="E -> K (in strain: NCTC 12894)"
FT   VARIANT         219
FT                   /note="S -> A (in strain: NCTC 12894)"
FT   VARIANT         342..343
FT                   /note="GD -> EGE (in strain: NCTC 12894)"
SQ   SEQUENCE   344 AA;  37161 MW;  5CF9C3AD5E045C52 CRC64;
     MDDNKRKSLD AALKSLDKTF GKGTILRLGD KEVEKIDSIP TGSVGLDLAL GIGGVPKGRI
     IEIYGPESSG KTTLTLHIIA ECQKKGGVCA FIDAEHALDV KYAKDLGVDT ENLYISQPDF
     GEQALEIVET IARSGAIDLI VVDSVAALTP KAEIEGDMGD QHVGLQARLM SQALRELTGI
     VHKMNTTVIF INQIRMKIGM MGYGTPETTT GGNALKFYSS VRLDVRKTAT LKQNDEPIGN
     RVKVKVAKNK VAPPFKQAEF DVMFGEGVSR EGELIDYGVK LDIIDKSGAW FSYKASKLGQ
     GRENAKAFLK ENPAIADEIT QAIQNSIGID SMILGAKEDD EGDE