RECA_CERS4
ID RECA_CERS4 Reviewed; 343 AA.
AC P32725; Q3J0R0;
DT 01-OCT-1993, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-1993, sequence version 1.
DT 03-AUG-2022, entry version 117.
DE RecName: Full=Protein RecA {ECO:0000255|HAMAP-Rule:MF_00268};
DE AltName: Full=Recombinase A {ECO:0000255|HAMAP-Rule:MF_00268};
GN Name=recA {ECO:0000255|HAMAP-Rule:MF_00268}; OrderedLocusNames=RHOS4_20560;
GN ORFNames=RSP_0452;
OS Cereibacter sphaeroides (strain ATCC 17023 / DSM 158 / JCM 6121 / CCUG
OS 31486 / LMG 2827 / NBRC 12203 / NCIMB 8253 / ATH 2.4.1.) (Rhodobacter
OS sphaeroides).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Rhodobacterales;
OC Rhodobacteraceae; Cereibacter.
OX NCBI_TaxID=272943;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=8277942; DOI=10.1007/bf00277356;
RA Calero S., Fernandez de Henestrosa A.R., Barbe J.;
RT "Molecular cloning, sequence and regulation of expression of the recA gene
RT of the phototrophic bacterium Rhodobacter sphaeroides.";
RL Mol. Gen. Genet. 242:116-120(1994).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 17023 / DSM 158 / JCM 6121 / CCUG 31486 / LMG 2827 / NBRC 12203
RC / NCIMB 8253 / ATH 2.4.1.;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA Hammon N., Israni S., Pitluck S., Richardson P., Mackenzie C.,
RA Choudhary M., Larimer F., Hauser L.J., Land M., Donohue T.J., Kaplan S.;
RT "Complete sequence of chromosome 1 of Rhodobacter sphaeroides 2.4.1.";
RL Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Can catalyze the hydrolysis of ATP in the presence of single-
CC stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex
CC DNA, and the ATP-dependent hybridization of homologous single-stranded
CC DNAs. It interacts with LexA causing its activation and leading to its
CC autocatalytic cleavage.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00268}.
CC -!- SIMILARITY: Belongs to the RecA family. {ECO:0000255|HAMAP-
CC Rule:MF_00268}.
CC -!- SEQUENCE CAUTION:
CC Sequence=ABA79624.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; X72705; CAA51258.1; -; Genomic_DNA.
DR EMBL; CP000143; ABA79624.1; ALT_INIT; Genomic_DNA.
DR PIR; S41560; S41560.
DR RefSeq; YP_353525.1; NC_007493.2.
DR AlphaFoldDB; P32725; -.
DR SMR; P32725; -.
DR STRING; 272943.RSP_0452; -.
DR EnsemblBacteria; ABA79624; ABA79624; RSP_0452.
DR KEGG; rsp:RSP_0452; -.
DR PATRIC; fig|272943.9.peg.2401; -.
DR eggNOG; COG0468; Bacteria.
DR Proteomes; UP000002703; Chromosome 1.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0003684; F:damaged DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003697; F:single-stranded DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-UniRule.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-UniRule.
DR GO; GO:0009432; P:SOS response; IEA:UniProtKB-UniRule.
DR CDD; cd00983; recA; 1.
DR Gene3D; 3.40.50.300; -; 1.
DR HAMAP; MF_00268; RecA; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR013765; DNA_recomb/repair_RecA.
DR InterPro; IPR020584; DNA_recomb/repair_RecA_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR020588; RecA_ATP-bd.
DR InterPro; IPR023400; RecA_C.
DR InterPro; IPR020587; RecA_monomer-monomer_interface.
DR PANTHER; PTHR45900; PTHR45900; 1.
DR Pfam; PF00154; RecA; 1.
DR PRINTS; PR00142; RECA.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR SUPFAM; SSF54752; SSF54752; 1.
DR TIGRFAMs; TIGR02012; tigrfam_recA; 1.
DR PROSITE; PS00321; RECA_1; 1.
DR PROSITE; PS50162; RECA_2; 1.
DR PROSITE; PS50163; RECA_3; 1.
PE 3: Inferred from homology;
KW ATP-binding; Cytoplasm; DNA damage; DNA recombination; DNA repair;
KW DNA-binding; Nucleotide-binding; Reference proteome; SOS response.
FT CHAIN 1..343
FT /note="Protein RecA"
FT /id="PRO_0000122819"
FT BINDING 64..71
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00268"
SQ SEQUENCE 343 AA; 36698 MW; 40584E781E5CADFD CRC64;
MDKAKALESA LAQIERQFGK GSIMKLGANS PVMEIEATST GSLGLDIALG IGGLPKGRII
EIYGPESSGK TTLTLHVVAE EQKKGGVCAF VDAEHALDPQ YAKKLGVNLD ELLISQPDTG
EQALEIVDTL VRSGAVNLIV VDSVAALTPK SEIEGDMGDM QMGSQARLMS QAMRKLTASI
GRSNCMVIFI NQIRMKIGVM FGNPETTTGG NALKFYASVR LDIRRTGAIK DRDNVIGNTT
KVKVVKNKVA PPFREVEFDI MYGEGISKTG ELVDLGVKAG VVEKSGSWYS YGDERIGQGR
ENAKAFLRAN PTVAGDIEDR IRASHGLDFS TGEDGKGDDL VDM
