ID   RECA_CHLAA              Reviewed;         351 AA.
AC   O52394; A9W9V1;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   18-MAR-2008, sequence version 2.
DT   03-AUG-2022, entry version 125.
DE   RecName: Full=Protein RecA {ECO:0000255|HAMAP-Rule:MF_00268};
DE   AltName: Full=Recombinase A {ECO:0000255|HAMAP-Rule:MF_00268};
GN   Name=recA {ECO:0000255|HAMAP-Rule:MF_00268}; OrderedLocusNames=Caur_1359;
OS   Chloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl).
OC   Bacteria; Chloroflexi; Chloroflexia; Chloroflexales; Chloroflexineae;
OC   Chloroflexaceae; Chloroflexus.
OX   NCBI_TaxID=324602;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=9595663; DOI=10.1111/j.1574-6968.1998.tb12978.x;
RA   Gruber T.M., Eisen J.A., Gish K., Bryant D.A.;
RT   "The phylogenetic relationships of Chlorobium tepidum and Chloroflexus
RT   aurantiacus based upon their RecA sequences.";
RL   FEMS Microbiol. Lett. 162:53-60(1998).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29366 / DSM 635 / J-10-fl;
RX   PubMed=21714912; DOI=10.1186/1471-2164-12-334;
RA   Tang K.H., Barry K., Chertkov O., Dalin E., Han C.S., Hauser L.J.,
RA   Honchak B.M., Karbach L.E., Land M.L., Lapidus A., Larimer F.W.,
RA   Mikhailova N., Pitluck S., Pierson B.K., Blankenship R.E.;
RT   "Complete genome sequence of the filamentous anoxygenic phototrophic
RT   bacterium Chloroflexus aurantiacus.";
RL   BMC Genomics 12:334-334(2011).
CC   -!- FUNCTION: Can catalyze the hydrolysis of ATP in the presence of single-
CC       stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex
CC       DNA, and the ATP-dependent hybridization of homologous single-stranded
CC       DNAs. It interacts with LexA causing its activation and leading to its
CC       autocatalytic cleavage. {ECO:0000255|HAMAP-Rule:MF_00268}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00268}.
CC   -!- SIMILARITY: Belongs to the RecA family. {ECO:0000255|HAMAP-
CC       Rule:MF_00268}.
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DR   EMBL; AF037259; AAC38570.1; -; Genomic_DNA.
DR   EMBL; CP000909; ABY34587.1; -; Genomic_DNA.
DR   RefSeq; WP_012257243.1; NC_010175.1.
DR   RefSeq; YP_001634976.1; NC_010175.1.
DR   AlphaFoldDB; O52394; -.
DR   SMR; O52394; -.
DR   STRING; 324602.Caur_1359; -.
DR   EnsemblBacteria; ABY34587; ABY34587; Caur_1359.
DR   KEGG; cau:Caur_1359; -.
DR   PATRIC; fig|324602.8.peg.1550; -.
DR   eggNOG; COG0468; Bacteria.
DR   HOGENOM; CLU_040469_3_2_0; -.
DR   InParanoid; O52394; -.
DR   OMA; DYGEQAL; -.
DR   Proteomes; UP000002008; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR   GO; GO:0003684; F:damaged DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003697; F:single-stranded DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-UniRule.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-UniRule.
DR   GO; GO:0009432; P:SOS response; IEA:UniProtKB-UniRule.
DR   CDD; cd00983; recA; 1.
DR   Gene3D; 3.40.50.300; -; 1.
DR   HAMAP; MF_00268; RecA; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR013765; DNA_recomb/repair_RecA.
DR   InterPro; IPR020584; DNA_recomb/repair_RecA_CS.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR020588; RecA_ATP-bd.
DR   InterPro; IPR023400; RecA_C.
DR   InterPro; IPR020587; RecA_monomer-monomer_interface.
DR   PANTHER; PTHR45900; PTHR45900; 1.
DR   Pfam; PF00154; RecA; 1.
DR   PRINTS; PR00142; RECA.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   SUPFAM; SSF54752; SSF54752; 1.
DR   TIGRFAMs; TIGR02012; tigrfam_recA; 1.
DR   PROSITE; PS00321; RECA_1; 1.
DR   PROSITE; PS50162; RECA_2; 1.
DR   PROSITE; PS50163; RECA_3; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cytoplasm; DNA damage; DNA recombination; DNA repair;
KW   DNA-binding; Nucleotide-binding; Reference proteome; SOS response.
FT   CHAIN           1..351
FT                   /note="Protein RecA"
FT                   /id="PRO_0000122682"
FT   BINDING         68..75
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00268"
FT   CONFLICT        37
FT                   /note="L -> V (in Ref. 1; AAC38570)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        205..207
FT                   /note="FGS -> LGT (in Ref. 1; AAC38570)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        221
FT                   /note="A -> T (in Ref. 1; AAC38570)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        257
FT                   /note="F -> Y (in Ref. 1; AAC38570)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   351 AA;  37837 MW;  728390295E35FD9C CRC64;
     MAITPEKEKA LAATMAQIDR KFGKGSIMKM GEASSRLAIE AIPTGSIALD IALGIGGVPR
     GRVVEIFGPE SSGKTTLAQH IIAEAQKMGG VCAFIDAEHA FDPVYAARCG VNIDDLLVSQ
     PDTGEQALEI CEMLVRSNAI DVIVIDSVAA LVPRAEIEGE MGDSMPGMQA RLMSQALRKL
     SGAISKSRTV VIFINQLRMK IGVMFGSPET TTGGQALKFY ASVRLDIRRV ETLKQGQEAI
     GSRVRVKVIK NKVAPPFRQA EFDILANEGI SREGNIIDIG TELGIIRKSG AWFYLGEDRL
     GQGRENVREF LKNNPALTDE IERLIKAQAL TNPTVIAPSV DVGDDDAIFE E