ID   RECA_CHLTR              Reviewed;         352 AA.
AC   P0CD80; O84656; P48287;
DT   02-MAR-2010, integrated into UniProtKB/Swiss-Prot.
DT   02-MAR-2010, sequence version 1.
DT   03-AUG-2022, entry version 62.
DE   RecName: Full=Protein RecA {ECO:0000255|HAMAP-Rule:MF_00268};
DE   AltName: Full=Recombinase A {ECO:0000255|HAMAP-Rule:MF_00268};
GN   Name=recA {ECO:0000255|HAMAP-Rule:MF_00268}; OrderedLocusNames=CT_650;
OS   Chlamydia trachomatis (strain D/UW-3/Cx).
OC   Bacteria; Chlamydiae; Chlamydiales; Chlamydiaceae;
OC   Chlamydia/Chlamydophila group; Chlamydia.
OX   NCBI_TaxID=272561;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=L2;
RX   PubMed=7822038; DOI=10.1128/iai.63.2.676-680.1995;
RA   Zhang D.J., Fan H., McClarty G., Brunham R.C.;
RT   "Identification of the Chlamydia trachomatis RecA-encoding gene.";
RL   Infect. Immun. 63:676-680(1995).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=L2;
RA   Pohlner J.;
RT   "Sequence of the recA gene from Chlamydia trachomatis L2.";
RL   Submitted (APR-1994) to the EMBL/GenBank/DDBJ databases.
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=D/UW-3/Cx;
RX   PubMed=9784136; DOI=10.1126/science.282.5389.754;
RA   Stephens R.S., Kalman S., Lammel C.J., Fan J., Marathe R., Aravind L.,
RA   Mitchell W.P., Olinger L., Tatusov R.L., Zhao Q., Koonin E.V., Davis R.W.;
RT   "Genome sequence of an obligate intracellular pathogen of humans: Chlamydia
RT   trachomatis.";
RL   Science 282:754-759(1998).
CC   -!- FUNCTION: Can catalyze the hydrolysis of ATP in the presence of single-
CC       stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex
CC       DNA, and the ATP-dependent hybridization of homologous single-stranded
CC       DNAs. It interacts with LexA causing its activation and leading to its
CC       autocatalytic cleavage. {ECO:0000255|HAMAP-Rule:MF_00268}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00268}.
CC   -!- SIMILARITY: Belongs to the RecA family. {ECO:0000255|HAMAP-
CC       Rule:MF_00268}.
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DR   EMBL; U15281; AAA75588.1; -; Genomic_DNA.
DR   EMBL; Z32530; CAA83539.1; -; Genomic_DNA.
DR   EMBL; AE001273; AAC68827.1; -; Genomic_DNA.
DR   PIR; H71488; H71488.
DR   RefSeq; NP_220168.1; NC_000117.1.
DR   RefSeq; WP_010725291.1; NC_000117.1.
DR   AlphaFoldDB; P0CD80; -.
DR   SMR; P0CD80; -.
DR   STRING; 813.O172_03565; -.
DR   EnsemblBacteria; AAC68827; AAC68827; CT_650.
DR   GeneID; 884433; -.
DR   KEGG; ctr:CT_650; -.
DR   PATRIC; fig|272561.5.peg.714; -.
DR   HOGENOM; CLU_040469_3_2_0; -.
DR   InParanoid; P0CD80; -.
DR   OMA; DYGEQAL; -.
DR   Proteomes; UP000000431; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR   GO; GO:0003684; F:damaged DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003697; F:single-stranded DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-UniRule.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-UniRule.
DR   GO; GO:0009432; P:SOS response; IEA:UniProtKB-UniRule.
DR   CDD; cd00983; recA; 1.
DR   Gene3D; 3.40.50.300; -; 1.
DR   HAMAP; MF_00268; RecA; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR013765; DNA_recomb/repair_RecA.
DR   InterPro; IPR020584; DNA_recomb/repair_RecA_CS.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR020588; RecA_ATP-bd.
DR   InterPro; IPR023400; RecA_C.
DR   InterPro; IPR020587; RecA_monomer-monomer_interface.
DR   PANTHER; PTHR45900; PTHR45900; 1.
DR   Pfam; PF00154; RecA; 1.
DR   PRINTS; PR00142; RECA.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   SUPFAM; SSF54752; SSF54752; 1.
DR   TIGRFAMs; TIGR02012; tigrfam_recA; 1.
DR   PROSITE; PS00321; RECA_1; 1.
DR   PROSITE; PS50162; RECA_2; 1.
DR   PROSITE; PS50163; RECA_3; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cytoplasm; DNA damage; DNA recombination; DNA repair;
KW   DNA-binding; Nucleotide-binding; Reference proteome; SOS response.
FT   CHAIN           1..352
FT                   /note="Protein RecA"
FT                   /id="PRO_0000122687"
FT   BINDING         67..74
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00268"
FT   VARIANT         334
FT                   /note="V -> A (in strain: L2)"
FT   VARIANT         342
FT                   /note="A -> S (in strain: L2)"
SQ   SEQUENCE   352 AA;  37830 MW;  15C2C91C7DC9B8E4 CRC64;
     MSVPDRKRAL EAAIAYIEKQ FGAGSIMSLG KHSSAHEIST IKTGALSLDL ALGIGGVPKG
     RIVEIFGPES SGKTTLATHI VANAQKMGGV AAYIDAEHAL DPNYAALIGA NINDLMISQP
     DCGEDALSIA ELLARSGAVD VIVIDSVAAL VPKSELEGEI GDVHVGLQAR MMSQALRKLT
     ATLARTNTCA IFINQIREKI GVSFGNPETT TGGRALKFYS SIRIDIRRIG SIKGGENFDI
     GNRIKVKVAK NKLAPPFRTA EFDILFNEGI SSAGCIIDLA VEKNIIDKKG SWFNYQDRKL
     GQGREAVREE LKRNKELFHE LERRIYESVQ ASQVPAAACV DAESREVAEA AK