ID   RECA_LACPE              Reviewed;         378 AA.
AC   Q6KCK3;
DT   27-SEP-2005, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 76.
DE   RecName: Full=Protein RecA {ECO:0000255|HAMAP-Rule:MF_00268};
DE   AltName: Full=Recombinase A {ECO:0000255|HAMAP-Rule:MF_00268};
GN   Name=recA {ECO:0000255|HAMAP-Rule:MF_00268};
OS   Lactiplantibacillus pentosus (Lactobacillus pentosus).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Lactobacillaceae;
OC   Lactiplantibacillus.
OX   NCBI_TaxID=1589;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 8041 / DSM 20314 / BCRC 11053 / JCM 1558 / KCTC 3120 / LMG
RC   10755 / NBRC 106467 / NCDO 363 / NCIMB 8026 / 124-2;
RX   PubMed=16014493; DOI=10.1099/ijs.0.63333-0;
RA   Bringel F., Castioni A., Olukoya D.K., Felis G.E., Torriani S.,
RA   Dellaglio F.;
RT   "Lactobacillus plantarum subsp. argentoratensis subsp. nov., isolated from
RT   vegetable matrices.";
RL   Int. J. Syst. Evol. Microbiol. 55:1629-1634(2005).
CC   -!- FUNCTION: Can catalyze the hydrolysis of ATP in the presence of single-
CC       stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex
CC       DNA, and the ATP-dependent hybridization of homologous single-stranded
CC       DNAs. It interacts with LexA causing its activation and leading to its
CC       autocatalytic cleavage. {ECO:0000255|HAMAP-Rule:MF_00268}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00268}.
CC   -!- SIMILARITY: Belongs to the RecA family. {ECO:0000255|HAMAP-
CC       Rule:MF_00268}.
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DR   EMBL; AJ621666; CAF21791.1; -; Genomic_DNA.
DR   RefSeq; WP_050339350.1; NZ_RDCL01000052.1.
DR   AlphaFoldDB; Q6KCK3; -.
DR   SMR; Q6KCK3; -.
DR   STRING; 1589.GCA_001188985_02308; -.
DR   PRIDE; Q6KCK3; -.
DR   GeneID; 49394474; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR   GO; GO:0003684; F:damaged DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003697; F:single-stranded DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-UniRule.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-UniRule.
DR   GO; GO:0009432; P:SOS response; IEA:UniProtKB-UniRule.
DR   CDD; cd00983; recA; 1.
DR   Gene3D; 3.40.50.300; -; 1.
DR   HAMAP; MF_00268; RecA; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR013765; DNA_recomb/repair_RecA.
DR   InterPro; IPR020584; DNA_recomb/repair_RecA_CS.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR020588; RecA_ATP-bd.
DR   InterPro; IPR023400; RecA_C.
DR   InterPro; IPR020587; RecA_monomer-monomer_interface.
DR   PANTHER; PTHR45900; PTHR45900; 1.
DR   Pfam; PF00154; RecA; 1.
DR   PRINTS; PR00142; RECA.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   SUPFAM; SSF54752; SSF54752; 1.
DR   TIGRFAMs; TIGR02012; tigrfam_recA; 1.
DR   PROSITE; PS00321; RECA_1; 1.
DR   PROSITE; PS50162; RECA_2; 1.
DR   PROSITE; PS50163; RECA_3; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cytoplasm; DNA damage; DNA recombination; DNA repair;
KW   DNA-binding; Nucleotide-binding; SOS response.
FT   CHAIN           1..378
FT                   /note="Protein RecA"
FT                   /id="PRO_0000122735"
FT   REGION          325..378
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        325..355
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         65..72
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00268"
SQ   SEQUENCE   378 AA;  40690 MW;  0CF98BB77F20ADCF CRC64;
     MADARKAALD TALKKIEKNF GKGAIMRMGD AAQTTISTIS SGSLALDDAL GVGGYPRGRI
     VEIYGPESSG KTTVALHAVA EVQKQGGTAA YIDAENALDP VYAEHLGVNI DDLLLSQPDT
     GEQGLEIADA LVSSGAVDIL VVDSVAALVP RAEIEGEMGD AHVGLQARLM SQALRKLSGT
     LNKTKTIALF INQIREKVGV MFGNPETTPG GRALKFYATI RLEVRRAEQI KEGTNIIGNR
     VRIKVVKNKV APPFKRAEVD IMYGQGISQT GEIVDMAAEK DIVKKSGSWY SYGDDRIGQG
     RENAKKYLDE HPDVMAEIRQ KVRDAYGMDQ TGEEDDQADD KSKDKATKPS DKSQAQAKPK
     KPVATETSLD LDDSKTDK