ID   RECA_PRER2              Reviewed;         340 AA.
AC   Q59717; D5EVD4;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1997, sequence version 1.
DT   03-AUG-2022, entry version 119.
DE   RecName: Full=Protein RecA {ECO:0000255|HAMAP-Rule:MF_00268};
DE   AltName: Full=Recombinase A {ECO:0000255|HAMAP-Rule:MF_00268};
GN   Name=recA {ECO:0000255|HAMAP-Rule:MF_00268}; OrderedLocusNames=PRU_0066;
OS   Prevotella ruminicola (strain ATCC 19189 / JCM 8958 / 23).
OC   Bacteria; Bacteroidetes; Bacteroidia; Bacteroidales; Prevotellaceae;
OC   Prevotella.
OX   NCBI_TaxID=264731;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=8870252; DOI=10.1111/j.1574-6968.1996.tb08508.x;
RA   Aminov R.I., Nagamine T., Ogata K., Sugiura M., Tajima K., Benno Y.;
RT   "Cloning, sequencing and complementation analysis of the recA gene from
RT   Prevotella ruminicola.";
RL   FEMS Microbiol. Lett. 144:53-59(1996).
RN   [2]
RP   ERRATUM OF PUBMED:8870252.
RA   Aminov R.I., Nagamine T., Ogata K., Sugiura M., Tajima K., Benno Y.;
RL   FEMS Microbiol. Lett. 145:473-473(1996).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 19189 / JCM 8958 / 23;
RX   PubMed=20585943; DOI=10.1007/s00248-010-9692-8;
RA   Purushe J., Fouts D.E., Morrison M., White B.A., Mackie R.I.,
RA   Coutinho P.M., Henrissat B., Nelson K.E.;
RT   "Comparative genome analysis of Prevotella ruminicola and Prevotella
RT   bryantii: insights into their environmental niche.";
RL   Microb. Ecol. 60:721-729(2010).
CC   -!- FUNCTION: Can catalyze the hydrolysis of ATP in the presence of single-
CC       stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex
CC       DNA, and the ATP-dependent hybridization of homologous single-stranded
CC       DNAs. It interacts with LexA causing its activation and leading to its
CC       autocatalytic cleavage.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00268}.
CC   -!- SIMILARITY: Belongs to the RecA family. {ECO:0000255|HAMAP-
CC       Rule:MF_00268}.
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DR   EMBL; U61227; AAC44506.1; -; Genomic_DNA.
DR   EMBL; CP002006; ADE81933.1; -; Genomic_DNA.
DR   RefSeq; WP_013063920.1; NC_014033.1.
DR   AlphaFoldDB; Q59717; -.
DR   SMR; Q59717; -.
DR   STRING; 264731.PRU_0066; -.
DR   EnsemblBacteria; ADE81933; ADE81933; PRU_0066.
DR   GeneID; 31499624; -.
DR   KEGG; pru:PRU_0066; -.
DR   eggNOG; COG0468; Bacteria.
DR   HOGENOM; CLU_040469_1_2_10; -.
DR   OMA; DYGEQAL; -.
DR   OrthoDB; 1080436at2; -.
DR   Proteomes; UP000000927; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR   GO; GO:0003684; F:damaged DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003697; F:single-stranded DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-UniRule.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-UniRule.
DR   GO; GO:0009432; P:SOS response; IEA:UniProtKB-UniRule.
DR   CDD; cd00983; recA; 1.
DR   Gene3D; 3.40.50.300; -; 1.
DR   HAMAP; MF_00268; RecA; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR013765; DNA_recomb/repair_RecA.
DR   InterPro; IPR020584; DNA_recomb/repair_RecA_CS.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR020588; RecA_ATP-bd.
DR   InterPro; IPR023400; RecA_C.
DR   InterPro; IPR020587; RecA_monomer-monomer_interface.
DR   PANTHER; PTHR45900; PTHR45900; 1.
DR   Pfam; PF00154; RecA; 1.
DR   PRINTS; PR00142; RECA.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   SUPFAM; SSF54752; SSF54752; 1.
DR   TIGRFAMs; TIGR02012; tigrfam_recA; 1.
DR   PROSITE; PS00321; RECA_1; 1.
DR   PROSITE; PS50162; RECA_2; 1.
DR   PROSITE; PS50163; RECA_3; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cytoplasm; DNA damage; DNA recombination; DNA repair;
KW   DNA-binding; Nucleotide-binding; Reference proteome; SOS response.
FT   CHAIN           1..340
FT                   /note="Protein RecA"
FT                   /id="PRO_0000122794"
FT   BINDING         75..82
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00268"
SQ   SEQUENCE   340 AA;  36852 MW;  2DFFB8810C0F7CA3 CRC64;
     MAKEKDEALS PQQEKLKALQ AAMSKIEKDY GKGSIMRMGD EQIDNVEVIP TGSIGLNAAL
     GVGGYPKGRI IEIYGPESSG KTTLAIHAIA ECQKNGGIAA FIDAEHAFDR FYAAHLGVDV
     ENLYISQPDN GEQALEIADQ LIRSSAIDII VIDSVAALTP KKEIEGDMGD SAVGLQARLM
     SQALRKLTST ISKTNTTCIF INQLREKIGV MFGNPETTTG GNALKFYASV RLDIRKVTAI
     KDGDNIIGNQ VRVKVIKNKV APPFRKAEFE ITFGEGISKI GEIVDLGVEY EIIKKSGSWF
     SYGDSKLAQG RDAVKALLKD NPELCEELEA KIMEAIADKK