RECA_PROMI
ID RECA_PROMI Reviewed; 355 AA.
AC P11406;
DT 01-JUL-1989, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2007, sequence version 2.
DT 03-AUG-2022, entry version 127.
DE RecName: Full=Protein RecA {ECO:0000255|HAMAP-Rule:MF_00268};
DE AltName: Full=Recombinase A {ECO:0000255|HAMAP-Rule:MF_00268};
GN Name=recA {ECO:0000255|HAMAP-Rule:MF_00268};
OS Proteus mirabilis.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Morganellaceae; Proteus.
OX NCBI_TaxID=584;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=PG1300;
RX PubMed=2544862; DOI=10.1093/nar/17.11.4390;
RA Akaboshi E., Yip M.L.R., Howard-Flanders P.;
RT "Nucleotide sequence of the recA gene of Proteus mirabilis.";
RL Nucleic Acids Res. 17:4390-4390(1989).
CC -!- FUNCTION: Can catalyze the hydrolysis of ATP in the presence of single-
CC stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex
CC DNA, and the ATP-dependent hybridization of homologous single-stranded
CC DNAs. It interacts with LexA causing its activation and leading to its
CC autocatalytic cleavage. {ECO:0000255|HAMAP-Rule:MF_00268}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00268}.
CC -!- SIMILARITY: Belongs to the RecA family. {ECO:0000255|HAMAP-
CC Rule:MF_00268}.
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DR EMBL; X14870; CAA33015.1; -; Genomic_DNA.
DR PIR; S04606; RQEBPM.
DR RefSeq; WP_004247401.1; NZ_WURR01000003.1.
DR AlphaFoldDB; P11406; -.
DR SMR; P11406; -.
DR STRING; 584.AOUC001_13985; -.
DR PRIDE; P11406; -.
DR GeneID; 6803560; -.
DR PATRIC; fig|584.106.peg.943; -.
DR OMA; DYGEQAL; -.
DR OrthoDB; 1080436at2; -.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0003684; F:damaged DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003697; F:single-stranded DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-UniRule.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-UniRule.
DR GO; GO:0009432; P:SOS response; IEA:UniProtKB-UniRule.
DR CDD; cd00983; recA; 1.
DR Gene3D; 3.40.50.300; -; 1.
DR HAMAP; MF_00268; RecA; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR013765; DNA_recomb/repair_RecA.
DR InterPro; IPR020584; DNA_recomb/repair_RecA_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR020588; RecA_ATP-bd.
DR InterPro; IPR023400; RecA_C.
DR InterPro; IPR020587; RecA_monomer-monomer_interface.
DR PANTHER; PTHR45900; PTHR45900; 1.
DR Pfam; PF00154; RecA; 1.
DR PRINTS; PR00142; RECA.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR SUPFAM; SSF54752; SSF54752; 1.
DR TIGRFAMs; TIGR02012; tigrfam_recA; 1.
DR PROSITE; PS00321; RECA_1; 1.
DR PROSITE; PS50162; RECA_2; 1.
DR PROSITE; PS50163; RECA_3; 1.
PE 3: Inferred from homology;
KW ATP-binding; Cytoplasm; DNA damage; DNA recombination; DNA repair;
KW DNA-binding; Nucleotide-binding; SOS response.
FT INIT_MET 1
FT /note="Removed"
FT CHAIN 2..355
FT /note="Protein RecA"
FT /id="PRO_0000122797"
FT BINDING 67..74
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00268"
SQ SEQUENCE 355 AA; 38219 MW; 73F6D0B215F7E9D8 CRC64;
MAIDENKQKA LAAALGQIEK QFGKGSIMRL GEDRSMNVET ISTGSLSLDV ALGAGGLPRG
RIVEIYGPES SGKTTLTLQV IASAQREGKI CAFIDAEHAL DPIYAQKLGV DIDNLLCSQP
DTGEQALEIC DALSRSGAVD VIVVDSVAAL TPKAEIEGEI GDSHVGLAAR MMSQAMRKLA
GNLKNSNTLL IFINQIRMKI GVMFGNPETT TGGNALKFYA SVRLDIRRIG SVKNGDEVIG
SETRVKVVKN KVAAPFKQAE FQIMYGEGIN TYGELIDLGV KHKLVEKAGA WYSYNGEKIG
QGKANATNYL KEHPEMYNEL NTKLREMLLN HAGEFTSAAD FAGEESDSDA DDTKE
