RECA_RHOPA
ID RECA_RHOPA Reviewed; 349 AA.
AC Q9XBC1;
DT 01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT 29-MAR-2005, sequence version 3.
DT 03-AUG-2022, entry version 130.
DE RecName: Full=Protein RecA {ECO:0000255|HAMAP-Rule:MF_00268};
DE AltName: Full=Recombinase A {ECO:0000255|HAMAP-Rule:MF_00268};
GN Name=recA {ECO:0000255|HAMAP-Rule:MF_00268}; OrderedLocusNames=RPA3851;
OS Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC Bradyrhizobiaceae; Rhodopseudomonas.
OX NCBI_TaxID=258594;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=7;
RX PubMed=10376844; DOI=10.1099/13500872-145-5-1275;
RA Dumay V., Inui M., Yukawa H.;
RT "Molecular analysis of the recA gene and SOS box of the purple non-sulfur
RT bacterium Rhodopseudomonas palustris no. 7.";
RL Microbiology 145:1275-1285(1999).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-98 / CGA009;
RX PubMed=14704707; DOI=10.1038/nbt923;
RA Larimer F.W., Chain P., Hauser L., Lamerdin J.E., Malfatti S., Do L.,
RA Land M.L., Pelletier D.A., Beatty J.T., Lang A.S., Tabita F.R.,
RA Gibson J.L., Hanson T.E., Bobst C., Torres y Torres J.L., Peres C.,
RA Harrison F.H., Gibson J., Harwood C.S.;
RT "Complete genome sequence of the metabolically versatile photosynthetic
RT bacterium Rhodopseudomonas palustris.";
RL Nat. Biotechnol. 22:55-61(2004).
CC -!- FUNCTION: Can catalyze the hydrolysis of ATP in the presence of single-
CC stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex
CC DNA, and the ATP-dependent hybridization of homologous single-stranded
CC DNAs. It interacts with LexA causing its activation and leading to its
CC autocatalytic cleavage. {ECO:0000255|HAMAP-Rule:MF_00268}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00268}.
CC -!- SIMILARITY: Belongs to the RecA family. {ECO:0000255|HAMAP-
CC Rule:MF_00268}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAA78779.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC Sequence=CAE29292.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; D84467; BAA78779.1; ALT_INIT; Genomic_DNA.
DR EMBL; BX572605; CAE29292.1; ALT_INIT; Genomic_DNA.
DR AlphaFoldDB; Q9XBC1; -.
DR SMR; Q9XBC1; -.
DR STRING; 258594.RPA3851; -.
DR PRIDE; Q9XBC1; -.
DR EnsemblBacteria; CAE29292; CAE29292; RPA3851.
DR KEGG; rpa:RPA3851; -.
DR eggNOG; COG0468; Bacteria.
DR HOGENOM; CLU_040469_1_2_5; -.
DR PhylomeDB; Q9XBC1; -.
DR Proteomes; UP000001426; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0003684; F:damaged DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003697; F:single-stranded DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-UniRule.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-UniRule.
DR GO; GO:0009432; P:SOS response; IEA:UniProtKB-UniRule.
DR CDD; cd00983; recA; 1.
DR Gene3D; 3.40.50.300; -; 1.
DR HAMAP; MF_00268; RecA; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR013765; DNA_recomb/repair_RecA.
DR InterPro; IPR020584; DNA_recomb/repair_RecA_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR020588; RecA_ATP-bd.
DR InterPro; IPR023400; RecA_C.
DR InterPro; IPR020587; RecA_monomer-monomer_interface.
DR PANTHER; PTHR45900; PTHR45900; 1.
DR Pfam; PF00154; RecA; 1.
DR PRINTS; PR00142; RECA.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR SUPFAM; SSF54752; SSF54752; 1.
DR TIGRFAMs; TIGR02012; tigrfam_recA; 1.
DR PROSITE; PS00321; RECA_1; 1.
DR PROSITE; PS50162; RECA_2; 1.
DR PROSITE; PS50163; RECA_3; 1.
PE 3: Inferred from homology;
KW ATP-binding; Cytoplasm; DNA damage; DNA recombination; DNA repair;
KW DNA-binding; Nucleotide-binding; Reference proteome; SOS response.
FT CHAIN 1..349
FT /note="Protein RecA"
FT /id="PRO_0000122818"
FT BINDING 64..71
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00268"
FT CONFLICT 25
FT /note="R -> K (in Ref. 1; BAA78779)"
FT /evidence="ECO:0000305"
FT CONFLICT 32..34
FT /note="SMD -> AME (in Ref. 1; BAA78779)"
FT /evidence="ECO:0000305"
FT CONFLICT 91
FT /note="V -> I (in Ref. 1; BAA78779)"
FT /evidence="ECO:0000305"
FT CONFLICT 228
FT /note="Q -> A (in Ref. 1; BAA78779)"
FT /evidence="ECO:0000305"
FT CONFLICT 236
FT /note="V -> I (in Ref. 1; BAA78779)"
FT /evidence="ECO:0000305"
FT CONFLICT 291
FT /note="H -> Y (in Ref. 1; BAA78779)"
FT /evidence="ECO:0000305"
FT CONFLICT 305
FT /note="A -> S (in Ref. 1; BAA78779)"
FT /evidence="ECO:0000305"
FT CONFLICT 308..309
FT /note="KA -> RS (in Ref. 1; BAA78779)"
FT /evidence="ECO:0000305"
FT CONFLICT 339
FT /note="S -> R (in Ref. 1; BAA78779)"
FT /evidence="ECO:0000305"
FT CONFLICT 347
FT /note="M -> I (in Ref. 1; BAA78779)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 349 AA; 37403 MW; 67E1EBBAB1D06DEB CRC64;
MDKSKALSAA LSQIERQFGK GSVMRLGKND RSMDIETISS GSLGLDIALG VGGLPKGRIV
EIYGPESSGK TTLALHCVAE AQKKGGICAF VDAEHALDPV YARKLGVNVD DLLISQPDHG
EQALEIADTL VRSGAIDVLI VDSVAALVPR AELEGEMGDA LPGLQARLMS QALRKLTASI
NKSNTMVIFI NQIRMKIGVM YGSPETTTGG NALKFYASVR LDIRRIGQIK ERDEVVGNQT
RVKVVKNKLA PPFKQVEFDI MYGEGVSKMG EILDLGVKAG IVEKSGAWFS HDSQRLGQGR
ENAKAFLKAN PDMTAKIEAA IRQNSGLIAE QILAGSPESD ADGEEPMEE
