RECA_RUMA7
ID RECA_RUMA7 Reviewed; 398 AA.
AC P49985; E6UC75;
DT 01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT 03-MAY-2011, sequence version 2.
DT 03-AUG-2022, entry version 110.
DE RecName: Full=Protein RecA {ECO:0000255|HAMAP-Rule:MF_00268};
DE AltName: Full=Recombinase A {ECO:0000255|HAMAP-Rule:MF_00268};
GN Name=recA {ECO:0000255|HAMAP-Rule:MF_00268}; OrderedLocusNames=Rumal_2211;
OS Ruminococcus albus (strain ATCC 27210 / DSM 20455 / JCM 14654 / NCDO 2250 /
OS 7).
OC Bacteria; Firmicutes; Clostridia; Eubacteriales; Oscillospiraceae;
OC Ruminococcus.
OX NCBI_TaxID=697329;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 27210 / DSM 20455 / JCM 14654 / NCDO 2250 / 7;
RX PubMed=21914885; DOI=10.1128/jb.05621-11;
RA Suen G., Stevenson D.M., Bruce D.C., Chertkov O., Copeland A., Cheng J.F.,
RA Detter C., Detter J.C., Goodwin L.A., Han C.S., Hauser L.J., Ivanova N.N.,
RA Kyrpides N.C., Land M.L., Lapidus A., Lucas S., Ovchinnikova G.,
RA Pitluck S., Tapia R., Woyke T., Boyum J., Mead D., Weimer P.J.;
RT "Complete genome of the cellulolytic ruminal bacterium Ruminococcus albus
RT 7.";
RL J. Bacteriol. 193:5574-5575(2011).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 109-229.
RC STRAIN=ATCC 27210 / DSM 20455 / JCM 14654 / NCDO 2250 / 7;
RA Aminov R.I., Nagamine T., Ogata K., Benno Y.;
RL Submitted (JUN-1995) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Can catalyze the hydrolysis of ATP in the presence of single-
CC stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex
CC DNA, and the ATP-dependent hybridization of homologous single-stranded
CC DNAs. It interacts with LexA causing its activation and leading to its
CC autocatalytic cleavage. {ECO:0000255|HAMAP-Rule:MF_00268}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00268}.
CC -!- SIMILARITY: Belongs to the RecA family. {ECO:0000255|HAMAP-
CC Rule:MF_00268}.
CC -!- CAUTION: Sequence (AAA73925.1) highly divergent from genome sequence.
CC It could originate from another bacterial species. {ECO:0000305}.
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DR EMBL; CP002403; ADU22697.1; -; Genomic_DNA.
DR EMBL; U30293; AAA73925.1; -; Genomic_DNA.
DR RefSeq; WP_013498854.1; NZ_JHYT01000008.1.
DR AlphaFoldDB; P49985; -.
DR SMR; P49985; -.
DR STRING; 697329.Rumal_2211; -.
DR EnsemblBacteria; ADU22697; ADU22697; Rumal_2211.
DR KEGG; ral:Rumal_2211; -.
DR eggNOG; COG0468; Bacteria.
DR HOGENOM; CLU_040469_3_2_9; -.
DR OMA; DYGEQAL; -.
DR OrthoDB; 1080436at2; -.
DR Proteomes; UP000006919; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0003684; F:damaged DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003697; F:single-stranded DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-UniRule.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-UniRule.
DR GO; GO:0009432; P:SOS response; IEA:UniProtKB-UniRule.
DR CDD; cd00983; recA; 1.
DR Gene3D; 3.40.50.300; -; 1.
DR HAMAP; MF_00268; RecA; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR013765; DNA_recomb/repair_RecA.
DR InterPro; IPR020584; DNA_recomb/repair_RecA_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR020588; RecA_ATP-bd.
DR InterPro; IPR023400; RecA_C.
DR InterPro; IPR020587; RecA_monomer-monomer_interface.
DR PANTHER; PTHR45900; PTHR45900; 1.
DR Pfam; PF00154; RecA; 1.
DR PRINTS; PR00142; RECA.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR SUPFAM; SSF54752; SSF54752; 1.
DR TIGRFAMs; TIGR02012; tigrfam_recA; 1.
DR PROSITE; PS00321; RECA_1; 1.
DR PROSITE; PS50162; RECA_2; 1.
DR PROSITE; PS50163; RECA_3; 1.
PE 3: Inferred from homology;
KW ATP-binding; Cytoplasm; DNA damage; DNA recombination; DNA repair;
KW DNA-binding; Nucleotide-binding; SOS response.
FT CHAIN 1..398
FT /note="Protein RecA"
FT /id="PRO_0000122825"
FT REGION 351..398
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 83..90
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00268"
FT CONFLICT 109..112
FT /note="FIDV -> LIEA (in Ref. 2; AAA73925)"
FT /evidence="ECO:0000305"
FT CONFLICT 119
FT /note="V -> Q (in Ref. 2; AAA73925)"
FT /evidence="ECO:0000305"
FT CONFLICT 122..123
FT /note="KN -> TA (in Ref. 2; AAA73925)"
FT /evidence="ECO:0000305"
FT CONFLICT 127..133
FT /note="DIDSMLV -> QINDLLL (in Ref. 2; AAA73925)"
FT /evidence="ECO:0000305"
FT CONFLICT 138
FT /note="S -> T (in Ref. 2; AAA73925)"
FT /evidence="ECO:0000305"
FT CONFLICT 142
FT /note="A -> G (in Ref. 2; AAA73925)"
FT /evidence="ECO:0000305"
FT CONFLICT 147
FT /note="E -> D (in Ref. 2; AAA73925)"
FT /evidence="ECO:0000305"
FT CONFLICT 150..151
FT /note="AR -> IA (in Ref. 2; AAA73925)"
FT /evidence="ECO:0000305"
FT CONFLICT 155..160
FT /note="IDCIVI -> VDIVVV (in Ref. 2; AAA73925)"
FT /evidence="ECO:0000305"
FT CONFLICT 166..169
FT /note="MVTK -> LVPR (in Ref. 2; AAA73925)"
FT /evidence="ECO:0000305"
FT CONFLICT 173
FT /note="D -> E (in Ref. 2; AAA73925)"
FT /evidence="ECO:0000305"
FT CONFLICT 183..184
FT /note="QL -> LQ (in Ref. 2; AAA73925)"
FT /evidence="ECO:0000305"
FT CONFLICT 192
FT /note="M -> L (in Ref. 2; AAA73925)"
FT /evidence="ECO:0000305"
FT CONFLICT 196..207
FT /note="TGVVSKSNTTCV -> SGEINKTKTIAI (in Ref. 2; AAA73925)"
FT /evidence="ECO:0000305"
FT CONFLICT 212
FT /note="V -> I (in Ref. 2; AAA73925)"
FT /evidence="ECO:0000305"
FT CONFLICT 216
FT /note="I -> V (in Ref. 2; AAA73925)"
FT /evidence="ECO:0000305"
FT CONFLICT 220
FT /note="Y -> F (in Ref. 2; AAA73925)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 398 AA; 42820 MW; 4D81F699404E3303 CRC64;
MAIDKKKKEK DVKVHNITDA EEKKKALETA IAFIEKQFGK GAIMKLGDAR AMDVEAIPTG
SMMLDMALGI GGVPRGRIIE IYGPESSGKT TVALHIIAET QKMGGEVAFI DVEHALDPVY
AKNLGVDIDS MLVSQPDSGE QALEIAEALA RSGAIDCIVI DSVAAMVTKA EIDGEMGDTH
VGQLARLMSQ AMRKLTGVVS KSNTTCVFIN QVREKIGVMY GNPETTPGGR ALKFYASVRI
EVRRGEQIKD GGEVLGNRTK CKVVKNKVAP PFKECEFDIM YGKGISRVGE VLDTAVDLGI
VKKGGAWFSY EDYKLGQGRD NSKQFLLDHP DIMAEIENKI KASSAEMIAA AGQKNDKKSK
LEEKANAGAG ISEASEPDSS AEEDFEEFAP IDIGSLGE
