ID   RECA_TRIV2              Reviewed;         358 AA.
AC   P14167; Q3M3B4;
DT   01-JAN-1990, integrated into UniProtKB/Swiss-Prot.
DT   04-APR-2006, sequence version 2.
DT   03-AUG-2022, entry version 140.
DE   RecName: Full=Protein RecA {ECO:0000255|HAMAP-Rule:MF_00268};
DE   AltName: Full=Recombinase A {ECO:0000255|HAMAP-Rule:MF_00268};
GN   Name=recA {ECO:0000255|HAMAP-Rule:MF_00268}; OrderedLocusNames=Ava_4925;
OS   Trichormus variabilis (strain ATCC 29413 / PCC 7937) (Anabaena variabilis).
OC   Bacteria; Cyanobacteria; Nostocales; Nostocaceae; Trichormus.
OX   NCBI_TaxID=240292;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=2507530; DOI=10.1128/jb.171.10.5713-5719.1989;
RA   Owttrim G.W., Coleman J.R.;
RT   "Regulation of expression and nucleotide sequence of the Anabaena
RT   variabilis recA gene.";
RL   J. Bacteriol. 171:5713-5719(1989).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29413 / PCC 7937;
RX   PubMed=25197444; DOI=10.4056/sigs.3899418;
RA   Thiel T., Pratte B.S., Zhong J., Goodwin L., Copeland A., Lucas S., Han C.,
RA   Pitluck S., Land M.L., Kyrpides N.C., Woyke T.;
RT   "Complete genome sequence of Anabaena variabilis ATCC 29413.";
RL   Stand. Genomic Sci. 9:562-573(2014).
CC   -!- FUNCTION: Can catalyze the hydrolysis of ATP in the presence of single-
CC       stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex
CC       DNA, and the ATP-dependent hybridization of homologous single-stranded
CC       DNAs. It interacts with LexA causing its activation and leading to its
CC       autocatalytic cleavage.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00268}.
CC   -!- SIMILARITY: Belongs to the RecA family. {ECO:0000255|HAMAP-
CC       Rule:MF_00268}.
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DR   EMBL; M29680; AAA22031.1; -; Genomic_DNA.
DR   EMBL; CP000117; ABA24522.1; -; Genomic_DNA.
DR   PIR; A33606; RQAIA.
DR   AlphaFoldDB; P14167; -.
DR   SMR; P14167; -.
DR   STRING; 240292.Ava_4925; -.
DR   EnsemblBacteria; ABA24522; ABA24522; Ava_4925.
DR   KEGG; ava:Ava_4925; -.
DR   eggNOG; COG0468; Bacteria.
DR   HOGENOM; CLU_040469_3_2_3; -.
DR   OMA; DYGEQAL; -.
DR   Proteomes; UP000002533; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR   GO; GO:0003684; F:damaged DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003697; F:single-stranded DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-UniRule.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-UniRule.
DR   GO; GO:0009432; P:SOS response; IEA:UniProtKB-UniRule.
DR   CDD; cd00983; recA; 1.
DR   Gene3D; 3.40.50.300; -; 1.
DR   HAMAP; MF_00268; RecA; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR013765; DNA_recomb/repair_RecA.
DR   InterPro; IPR020584; DNA_recomb/repair_RecA_CS.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR020588; RecA_ATP-bd.
DR   InterPro; IPR023400; RecA_C.
DR   InterPro; IPR020587; RecA_monomer-monomer_interface.
DR   PANTHER; PTHR45900; PTHR45900; 1.
DR   Pfam; PF00154; RecA; 1.
DR   PRINTS; PR00142; RECA.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   SUPFAM; SSF54752; SSF54752; 1.
DR   TIGRFAMs; TIGR02012; tigrfam_recA; 1.
DR   PROSITE; PS00321; RECA_1; 1.
DR   PROSITE; PS50162; RECA_2; 1.
DR   PROSITE; PS50163; RECA_3; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cytoplasm; DNA damage; DNA recombination; DNA repair;
KW   DNA-binding; Nucleotide-binding; SOS response.
FT   CHAIN           1..358
FT                   /note="Protein RecA"
FT                   /id="PRO_0000122641"
FT   BINDING         69..76
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00268"
FT   CONFLICT        61
FT                   /note="K -> R (in Ref. 1; AAA22031)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        100
FT                   /note="H -> Q (in Ref. 1; AAA22031)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        137
FT                   /note="R -> P (in Ref. 1; AAA22031)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   358 AA;  38447 MW;  055940C869AEE5FF CRC64;
     MAINTDTSGK QKALTMVLNQ IERSFGKGAI MRLGDATRMR VETISTGALT LDLALGGGLP
     KGRVIEIYGP ESSGKTTVAL HAIAEVQKEG GIAAFVDAEH ALDPTYASAL GVDIQNLLVS
     QPDTGESALE IVDQLVRSAA VDIVVIDSVA ALVPRAEIEG DMGDAHVGLQ ARLMSQALRK
     ITGNIGKSGC TVIFINQLRQ KIGVTYGSPE TTTGGNALKF YASVRLDIRR IQTLKKGTDE
     FGNRVKVKVA KNKVAPPFRI AEFDIIFGKG VSTLGCLVDL AEETGILLRK GAWYSYNGDN
     ISQGRDNAIK YLEEKPEFAE QIKQQVREKL DKGAVVSANS VAKANEEDEE DVDLDEEE