ID   RECDL_BACSU             Reviewed;         798 AA.
AC   O34481;
DT   24-NOV-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   03-AUG-2022, entry version 123.
DE   RecName: Full=ATP-dependent RecD-like DNA helicase {ECO:0000255|HAMAP-Rule:MF_01488};
DE            EC=3.6.4.12 {ECO:0000255|HAMAP-Rule:MF_01488};
GN   Name=yrrC; Synonyms=recD2; OrderedLocusNames=BSU27480;
OS   Bacillus subtilis (strain 168).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA   Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA   Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA   Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA   Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA   Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA   Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA   Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA   Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA   Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA   Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA   Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA   Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA   Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA   Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA   Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA   Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA   Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA   Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
CC   -!- FUNCTION: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase.
CC       Has no activity on blunt DNA or DNA with 3'-overhangs, requires at
CC       least 10 bases of 5'-ssDNA for helicase activity. {ECO:0000255|HAMAP-
CC       Rule:MF_01488}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_01488};
CC   -!- SIMILARITY: Belongs to the RecD family. RecD-like subfamily.
CC       {ECO:0000255|HAMAP-Rule:MF_01488}.
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DR   EMBL; AL009126; CAB14689.1; -; Genomic_DNA.
DR   PIR; A69979; A69979.
DR   RefSeq; NP_390625.1; NC_000964.3.
DR   RefSeq; WP_004398511.1; NZ_JNCM01000036.1.
DR   AlphaFoldDB; O34481; -.
DR   SMR; O34481; -.
DR   STRING; 224308.BSU27480; -.
DR   PaxDb; O34481; -.
DR   PRIDE; O34481; -.
DR   EnsemblBacteria; CAB14689; CAB14689; BSU_27480.
DR   GeneID; 937553; -.
DR   KEGG; bsu:BSU27480; -.
DR   PATRIC; fig|224308.179.peg.2986; -.
DR   eggNOG; COG0507; Bacteria.
DR   InParanoid; O34481; -.
DR   OMA; SHPQYGR; -.
DR   PhylomeDB; O34481; -.
DR   BioCyc; BSUB:BSU27480-MON; -.
DR   Proteomes; UP000001570; Chromosome.
DR   GO; GO:0009338; C:exodeoxyribonuclease V complex; IBA:GO_Central.
DR   GO; GO:0043139; F:5'-3' DNA helicase activity; IBA:GO_Central.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0017116; F:single-stranded DNA helicase activity; IBA:GO_Central.
DR   GO; GO:0006310; P:DNA recombination; IBA:GO_Central.
DR   Gene3D; 3.40.50.300; -; 2.
DR   HAMAP; MF_01488; RecD_like; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR006345; DNA_helicase_RecD-like.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR029493; RecD-like_HHH.
DR   InterPro; IPR041451; RecD-like_SH13.
DR   InterPro; IPR027785; UvrD-like_helicase_C.
DR   Pfam; PF14490; HHH_4; 1.
DR   Pfam; PF18335; SH3_13; 1.
DR   Pfam; PF13538; UvrD_C_2; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR01448; recD_rel; 1.
PE   3: Inferred from homology;
KW   ATP-binding; DNA-binding; Helicase; Hydrolase; Nucleotide-binding;
KW   Reference proteome.
FT   CHAIN           1..798
FT                   /note="ATP-dependent RecD-like DNA helicase"
FT                   /id="PRO_0000389133"
FT   BINDING         370..374
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01488"
SQ   SEQUENCE   798 AA;  89184 MW;  A8ADC7FF253A5DB7 CRC64;
     MQQHPDQLKL EEEPYLKGTV NTVIYHNDTN LYTVLKVKVT ETSEAIEDKA VSVTGYFPAL
     QEEETYTFYG KIVTHPKFGL QFQAEHFKKE IPTTKEGIIQ YLSSDLFEGI GKKTAEEIVK
     KLGDSAINKI LADASVLYDV PRLSKKKADT LAGALQRHQG LEQIMISLNQ FGFGPQLSMK
     IYQAYESETL EKIQENPYQL VKDVEGIGFG KADELGSRMG LSGNHPERVK AAILYTLETT
     CLSEGHTYIE TEQLIIDTQS LLNQSAREGQ RITEMDAANA IIALGENKDI VIEDGRCYFP
     SLFYAEQNVA KRVKHIASQT EYENQFPESE FLLALGELEE RMDVQYAPSQ KEAIQKALSS
     PMLLLTGGPG TGKTTVIRGI VELYGELHGV SLDPSAYKKD EAFPIVLAAP TGRAAKRMSE
     STGLPAVTIH RLLGWNGAEG FTHTEDQPIE GKLLIIDEAS MLDIWLANHL FKAIPDHIQI
     IIVGDEDQLP SVGPGQVLRD LLASQVIPTV RLTDIYRQAE GSSIVELAHQ MKNGLLPNNL
     TAPTKDRSFI RCGGSQIKEV VEKVVANALK KGYTAKDIQV LAPMYRGKAG INELNVMLQD
     ILNPPKEKRR ELKFGDVVYR TGDKILQLVN QPENNVFNGD IGEITSIFYA KENTEKEDMA
     VVSFDGNEMT FTKKDFNQFT HAYCCSIHKS QGSEFPIVVL PVVKGYYRML RRNLLYTAIT
     RAKKFLILCG EEEALEWGVK NNDATVRQTS LKNRLSVQVE EMDAELEALQ KELPFSVHDA
     NIGMEGITPF DFMKEEQQ