ID   RECF_BACFR              Reviewed;         370 AA.
AC   Q64XR8;
DT   16-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT   25-OCT-2004, sequence version 1.
DT   03-AUG-2022, entry version 96.
DE   RecName: Full=DNA replication and repair protein RecF {ECO:0000255|HAMAP-Rule:MF_00365};
GN   Name=recF {ECO:0000255|HAMAP-Rule:MF_00365}; OrderedLocusNames=BF0958;
OS   Bacteroides fragilis (strain YCH46).
OC   Bacteria; Bacteroidetes; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC   Bacteroides.
OX   NCBI_TaxID=295405;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=YCH46;
RX   PubMed=15466707; DOI=10.1073/pnas.0404172101;
RA   Kuwahara T., Yamashita A., Hirakawa H., Nakayama H., Toh H., Okada N.,
RA   Kuhara S., Hattori M., Hayashi T., Ohnishi Y.;
RT   "Genomic analysis of Bacteroides fragilis reveals extensive DNA inversions
RT   regulating cell surface adaptation.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:14919-14924(2004).
CC   -!- FUNCTION: The RecF protein is involved in DNA metabolism; it is
CC       required for DNA replication and normal SOS inducibility. RecF binds
CC       preferentially to single-stranded, linear DNA. It also seems to bind
CC       ATP. {ECO:0000255|HAMAP-Rule:MF_00365}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00365}.
CC   -!- SIMILARITY: Belongs to the RecF family. {ECO:0000255|HAMAP-
CC       Rule:MF_00365}.
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DR   EMBL; AP006841; BAD47708.1; -; Genomic_DNA.
DR   RefSeq; WP_005785234.1; NC_006347.1.
DR   RefSeq; YP_098242.1; NC_006347.1.
DR   AlphaFoldDB; Q64XR8; -.
DR   SMR; Q64XR8; -.
DR   STRING; 295405.BF0958; -.
DR   PRIDE; Q64XR8; -.
DR   EnsemblBacteria; BAD47708; BAD47708; BF0958.
DR   GeneID; 66330062; -.
DR   KEGG; bfr:BF0958; -.
DR   PATRIC; fig|295405.11.peg.960; -.
DR   HOGENOM; CLU_040267_0_1_10; -.
DR   OMA; GESWSYA; -.
DR   Proteomes; UP000002197; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR   GO; GO:0003697; F:single-stranded DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-UniRule.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR   GO; GO:0009432; P:SOS response; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.20.1050.90; -; 1.
DR   Gene3D; 3.40.50.300; -; 1.
DR   HAMAP; MF_00365; RecF; 1.
DR   InterPro; IPR001238; DNA-binding_RecF.
DR   InterPro; IPR018078; DNA-binding_RecF_CS.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR038729; Rad50/SbcC_AAA.
DR   InterPro; IPR042174; RecF_2.
DR   PANTHER; PTHR32182:SF0; PTHR32182:SF0; 1.
DR   Pfam; PF13476; AAA_23; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00611; recf; 1.
DR   PROSITE; PS00617; RECF_1; 1.
DR   PROSITE; PS00618; RECF_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cytoplasm; DNA damage; DNA repair; DNA replication;
KW   DNA-binding; Nucleotide-binding; SOS response.
FT   CHAIN           1..370
FT                   /note="DNA replication and repair protein RecF"
FT                   /id="PRO_0000236110"
FT   BINDING         30..37
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00365"
SQ   SEQUENCE   370 AA;  42925 MW;  0E870145BAC41F2C CRC64;
     MILKRISILN YKNLEQVELN FSAKLNCFFG QNGMGKTNLL DAVYFLSFCK SAGNPIDSQN
     IRHEQDFFVI QGFYEAMDGT PEEIYCGMKR RSKKQFKRNK KEYSRLSDHI GFIPLVMVSP
     ADSELIAGGS DERRRFMDVV ISQYDKEYLD ALIRYNKALV QRNTLLKSEQ PIEEELFLVW
     EEMMAQAGEV VFRKREAFIS EFIPIFQSFY SYISQDKEQV GLTYESHARN ASLLEVLKES
     RVRDKIMGYS LRGIHKDELN MLLGDFPIKR EGSQGQNKTY LVALKLAQFD FLKRTGSTVP
     LLLLDDIFDK LDASRVEQIV KLVAGDNFGQ IFITDTNREH LDRILYKVGS DYKMFRVESG
     AINEMEEKER