ID   RECF_MYCPA              Reviewed;         385 AA.
AC   Q9L7L5;
DT   27-APR-2001, integrated into UniProtKB/Swiss-Prot.
DT   15-MAR-2004, sequence version 2.
DT   03-AUG-2022, entry version 123.
DE   RecName: Full=DNA replication and repair protein RecF;
GN   Name=recF; OrderedLocusNames=MAP_0003;
OS   Mycolicibacterium paratuberculosis (strain ATCC BAA-968 / K-10)
OS   (Mycobacterium paratuberculosis).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium avium complex (MAC).
OX   NCBI_TaxID=262316;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Zhang Q., Kapur V.;
RT   "Genomic organization of the Mycobacterium avium subsp. paratuberculosis
RT   origin of replication region.";
RL   Submitted (JAN-2000) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-968 / K-10;
RX   PubMed=16116077; DOI=10.1073/pnas.0505662102;
RA   Li L., Bannantine J.P., Zhang Q., Amonsin A., May B.J., Alt D., Banerji N.,
RA   Kanjilal S., Kapur V.;
RT   "The complete genome sequence of Mycobacterium avium subspecies
RT   paratuberculosis.";
RL   Proc. Natl. Acad. Sci. U.S.A. 102:12344-12349(2005).
CC   -!- FUNCTION: The RecF protein is involved in DNA metabolism; it is
CC       required for DNA replication and normal SOS inducibility. RecF binds
CC       preferentially to single-stranded, linear DNA. It also seems to bind
CC       ATP (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the RecF family. {ECO:0000305}.
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DR   EMBL; AF222789; AAF33693.1; -; Genomic_DNA.
DR   EMBL; AE016958; AAS02320.1; -; Genomic_DNA.
DR   RefSeq; WP_003876778.1; NC_002944.2.
DR   AlphaFoldDB; Q9L7L5; -.
DR   SMR; Q9L7L5; -.
DR   STRING; 262316.MAP_0003; -.
DR   EnsemblBacteria; AAS02320; AAS02320; MAP_0003.
DR   KEGG; mpa:MAP_0003; -.
DR   PATRIC; fig|262316.17.peg.4; -.
DR   eggNOG; COG1195; Bacteria.
DR   HOGENOM; CLU_040267_1_1_11; -.
DR   OMA; GESWSYA; -.
DR   Proteomes; UP000000580; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003697; F:single-stranded DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-UniRule.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR   GO; GO:0009432; P:SOS response; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.20.1050.90; -; 1.
DR   Gene3D; 3.40.50.300; -; 1.
DR   HAMAP; MF_00365; RecF; 1.
DR   InterPro; IPR001238; DNA-binding_RecF.
DR   InterPro; IPR018078; DNA-binding_RecF_CS.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR003395; RecF/RecN/SMC_N.
DR   InterPro; IPR042174; RecF_2.
DR   PANTHER; PTHR32182:SF0; PTHR32182:SF0; 1.
DR   Pfam; PF02463; SMC_N; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00611; recf; 1.
DR   PROSITE; PS00617; RECF_1; 1.
DR   PROSITE; PS00618; RECF_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cytoplasm; DNA damage; DNA repair; DNA replication;
KW   DNA-binding; Nucleotide-binding; Reference proteome; SOS response.
FT   CHAIN           1..385
FT                   /note="DNA replication and repair protein RecF"
FT                   /id="PRO_0000196433"
FT   BINDING         30..37
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255"
FT   CONFLICT        175
FT                   /note="G -> S (in Ref. 1; AAF33693)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        310
FT                   /note="F -> Y (in Ref. 1; AAF33693)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   385 AA;  41956 MW;  191DF24FFB7ADF97 CRC64;
     MYVRHLGLRD FRSWAHADLE LQPGRTVFIG SNGFGKTNLL EALWYSSTLG SHRVGTDAPL
     IRAGADRAVV STIVVNDGRE CAVDLEIAAG RANKARLNRS PVRSTREVLG VLRAVLFAPE
     DLALVRGDPS ERRRYLDDLA TLRRPAIAAV RADYDKVLRQ RTALLKSLSG ARHRGDRGAL
     DTLDVWDSRL AEYGAQLMAA RIDLVNQLAP EVEKAYQLLA PGSRAASIGY RSSLGAAASA
     EVNAGDRDYL EAALLAGLAA HRDAELERGM CLVGPHRDDL ELWLGEQVAK GFASHGESWS
     LALSLRLAAF ELLRADESDP VLLLDDVFAE LDAARRRALA AVAESAEQVL VTAAVLEDIP
     TGWQARRLFV ELRDTDAGRV SELRP