ID   RECF_MYCSM              Reviewed;         384 AA.
AC   P0C561; P50916;
DT   10-JUL-2007, integrated into UniProtKB/Swiss-Prot.
DT   10-JUL-2007, sequence version 1.
DT   03-AUG-2022, entry version 53.
DE   RecName: Full=DNA replication and repair protein RecF;
GN   Name=recF;
OS   Mycolicibacterium smegmatis (Mycobacterium smegmatis).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycolicibacterium.
OX   NCBI_TaxID=1772;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 607 / DSM 43465 / JCM 20379 / NBRC 3207 / NRRL B-692;
RX   PubMed=8733228; DOI=10.1111/j.1365-2958.1996.tb02617.x;
RA   Salazar L., Fsihi H., De Rossi E., Riccardi G., Rios C., Cole S.T.,
RA   Takiff H.E.;
RT   "Organization of the origins of replication of the chromosomes of
RT   Mycobacterium smegmatis, Mycobacterium leprae and Mycobacterium
RT   tuberculosis and isolation of a functional origin from M. smegmatis.";
RL   Mol. Microbiol. 20:283-293(1996).
CC   -!- FUNCTION: The RecF protein is involved in DNA metabolism; it is
CC       required for DNA replication and normal SOS inducibility. RecF binds
CC       preferentially to single-stranded, linear DNA. It also seems to bind
CC       ATP (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the RecF family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; X92503; CAA63251.1; -; Genomic_DNA.
DR   PIR; S70989; S70989.
DR   RefSeq; WP_011726603.1; NZ_SIUA01000001.1.
DR   AlphaFoldDB; P0C561; -.
DR   SMR; P0C561; -.
DR   GeneID; 66738195; -.
DR   OMA; GESWSYA; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003697; F:single-stranded DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-UniRule.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR   GO; GO:0009432; P:SOS response; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.20.1050.90; -; 1.
DR   Gene3D; 3.40.50.300; -; 1.
DR   HAMAP; MF_00365; RecF; 1.
DR   InterPro; IPR001238; DNA-binding_RecF.
DR   InterPro; IPR018078; DNA-binding_RecF_CS.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR003395; RecF/RecN/SMC_N.
DR   InterPro; IPR042174; RecF_2.
DR   PANTHER; PTHR32182:SF0; PTHR32182:SF0; 1.
DR   Pfam; PF02463; SMC_N; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00611; recf; 1.
DR   PROSITE; PS00617; RECF_1; 1.
DR   PROSITE; PS00618; RECF_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cytoplasm; DNA damage; DNA repair; DNA replication;
KW   DNA-binding; Nucleotide-binding; SOS response.
FT   CHAIN           1..384
FT                   /note="DNA replication and repair protein RecF"
FT                   /id="PRO_0000196434"
FT   BINDING         30..37
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   384 AA;  41920 MW;  1F2045B42BA73262 CRC64;
     MFARHLGLTD FRSWARVDLD LEPGRTVFVG PNGFGKTNLV EALWYSATLG SHRVATDAPL
     IRAGAERAIV STIVVNEGRE LAVDLEITSG RANKARLNRS PVRSAREILG VLRAVLFSPE
     DLSLVRGDPG DRRRYLDELA TTRRPALAGV RADYDKVVRQ RTALLKTAAG ARYRGDRSVI
     DTLEVWDGHL AAHGAALVAS RVKLVEELQP EVEKAYQLLA PASRPAAIRY RSSVEAIEDA
     PGPESVEFYE AALLDALARR RDAELERGVC LVGPHRDDLE LRLGDQPAKG FASHGESWSM
     ALALRLGAYE LLCSDGVEPV LLLDDVFAEL DTSRRRALAT VAGSAEQVLV TAAVGEDIPE
     DWDARRVEIR MVEDDGGRVS MVAS