ID   RECF_PSEAE              Reviewed;         369 AA.
AC   Q9I7C3;
DT   04-MAY-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 1.
DT   03-AUG-2022, entry version 120.
DE   RecName: Full=DNA replication and repair protein RecF;
GN   Name=recF; OrderedLocusNames=PA0003;
OS   Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM
OS   14847 / LMG 12228 / 1C / PRS 101 / PAO1).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=208964;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C /
RC   PRS 101 / PAO1;
RX   PubMed=10984043; DOI=10.1038/35023079;
RA   Stover C.K., Pham X.-Q.T., Erwin A.L., Mizoguchi S.D., Warrener P.,
RA   Hickey M.J., Brinkman F.S.L., Hufnagle W.O., Kowalik D.J., Lagrou M.,
RA   Garber R.L., Goltry L., Tolentino E., Westbrock-Wadman S., Yuan Y.,
RA   Brody L.L., Coulter S.N., Folger K.R., Kas A., Larbig K., Lim R.M.,
RA   Smith K.A., Spencer D.H., Wong G.K.-S., Wu Z., Paulsen I.T., Reizer J.,
RA   Saier M.H. Jr., Hancock R.E.W., Lory S., Olson M.V.;
RT   "Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic
RT   pathogen.";
RL   Nature 406:959-964(2000).
CC   -!- FUNCTION: The RecF protein is involved in DNA metabolism; it is
CC       required for DNA replication and normal SOS inducibility. RecF binds
CC       preferentially to single-stranded, linear DNA. It also seems to bind
CC       ATP (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the RecF family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AE004091; AAG03393.1; -; Genomic_DNA.
DR   PIR; G83644; G83644.
DR   RefSeq; NP_064723.1; NC_002516.2.
DR   RefSeq; WP_003097265.1; NZ_QZGE01000012.1.
DR   AlphaFoldDB; Q9I7C3; -.
DR   SMR; Q9I7C3; -.
DR   STRING; 287.DR97_2952; -.
DR   PaxDb; Q9I7C3; -.
DR   PRIDE; Q9I7C3; -.
DR   DNASU; 879229; -.
DR   EnsemblBacteria; AAG03393; AAG03393; PA0003.
DR   GeneID; 879229; -.
DR   KEGG; pae:PA0003; -.
DR   PATRIC; fig|208964.12.peg.3; -.
DR   PseudoCAP; PA0003; -.
DR   HOGENOM; CLU_040267_0_0_6; -.
DR   InParanoid; Q9I7C3; -.
DR   OMA; GESWSYA; -.
DR   PhylomeDB; Q9I7C3; -.
DR   BioCyc; PAER208964:G1FZ6-3-MON; -.
DR   Proteomes; UP000002438; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003697; F:single-stranded DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR   GO; GO:0000731; P:DNA synthesis involved in DNA repair; IBA:GO_Central.
DR   GO; GO:0006302; P:double-strand break repair; IBA:GO_Central.
DR   GO; GO:0009432; P:SOS response; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.20.1050.90; -; 1.
DR   Gene3D; 3.40.50.300; -; 1.
DR   HAMAP; MF_00365; RecF; 1.
DR   InterPro; IPR001238; DNA-binding_RecF.
DR   InterPro; IPR018078; DNA-binding_RecF_CS.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR003395; RecF/RecN/SMC_N.
DR   InterPro; IPR042174; RecF_2.
DR   PANTHER; PTHR32182:SF0; PTHR32182:SF0; 1.
DR   Pfam; PF02463; SMC_N; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00611; recf; 1.
DR   PROSITE; PS00617; RECF_1; 1.
DR   PROSITE; PS00618; RECF_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cytoplasm; DNA damage; DNA repair; DNA replication;
KW   DNA-binding; Nucleotide-binding; Reference proteome; SOS response.
FT   CHAIN           1..369
FT                   /note="DNA replication and repair protein RecF"
FT                   /id="PRO_0000196443"
FT   BINDING         30..37
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   369 AA;  41459 MW;  19E880D8E7AC12C2 CRC64;
     MSLTRVSVTA VRNLHPVTLS PSPRINILYG DNGSGKTSVL EAIHLLGLAR SFRSARLQPV
     IQYEEAACTV FGQVMLANGI ASNLGISRER QGEFTIRIDG QNARSAAQLA ETLPLQLINP
     DSFRLLEGAP KIRRQFLDWG VFHVEPRFLP VWQRLQKALR QRNSWLRHGK LDPASQAAWD
     RELSLASDEI DAYRRSYIQA LKPVFEETLA ELVSLDDLTL SYYRGWDKDR DLLEVLASSL
     LRDQQMGHTQ AGPQRADLRI RLAGHNAAEI LSRGQQKLVV CALRIAQGHL INRAKRGQCV
     YLVDDLPSEL DEQHRMALCR LLEDLGCQVF ITCVDPQLLK DGWRTDTPVS MFHVEHGKVS
     QTTTIGSEA