RECF_RHIME
ID RECF_RHIME Reviewed; 374 AA.
AC P56903; O30497;
DT 30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT 30-MAY-2000, sequence version 1.
DT 03-AUG-2022, entry version 120.
DE RecName: Full=DNA replication and repair protein RecF;
GN Name=recF; OrderedLocusNames=R00188; ORFNames=SMc02863;
OS Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium
OS meliloti).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC Rhizobiaceae; Sinorhizobium/Ensifer group; Sinorhizobium.
OX NCBI_TaxID=266834;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1021;
RX PubMed=11481430; DOI=10.1073/pnas.161294398;
RA Capela D., Barloy-Hubler F., Gouzy J., Bothe G., Ampe F., Batut J.,
RA Boistard P., Becker A., Boutry M., Cadieu E., Dreano S., Gloux S.,
RA Godrie T., Goffeau A., Kahn D., Kiss E., Lelaure V., Masuy D., Pohl T.,
RA Portetelle D., Puehler A., Purnelle B., Ramsperger U., Renard C.,
RA Thebault P., Vandenbol M., Weidner S., Galibert F.;
RT "Analysis of the chromosome sequence of the legume symbiont Sinorhizobium
RT meliloti strain 1021.";
RL Proc. Natl. Acad. Sci. U.S.A. 98:9877-9882(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1021;
RX PubMed=11474104; DOI=10.1126/science.1060966;
RA Galibert F., Finan T.M., Long S.R., Puehler A., Abola P., Ampe F.,
RA Barloy-Hubler F., Barnett M.J., Becker A., Boistard P., Bothe G.,
RA Boutry M., Bowser L., Buhrmester J., Cadieu E., Capela D., Chain P.,
RA Cowie A., Davis R.W., Dreano S., Federspiel N.A., Fisher R.F., Gloux S.,
RA Godrie T., Goffeau A., Golding B., Gouzy J., Gurjal M., Hernandez-Lucas I.,
RA Hong A., Huizar L., Hyman R.W., Jones T., Kahn D., Kahn M.L., Kalman S.,
RA Keating D.H., Kiss E., Komp C., Lelaure V., Masuy D., Palm C., Peck M.C.,
RA Pohl T.M., Portetelle D., Purnelle B., Ramsperger U., Surzycki R.,
RA Thebault P., Vandenbol M., Vorhoelter F.J., Weidner S., Wells D.H.,
RA Wong K., Yeh K.-C., Batut J.;
RT "The composite genome of the legume symbiont Sinorhizobium meliloti.";
RL Science 293:668-672(2001).
RN [3]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-176.
RC STRAIN=SU47 / 1021;
RX PubMed=9696772; DOI=10.1128/jb.180.16.4219-4226.1998;
RA Bardin S.D., Voegele R.T., Finan T.M.;
RT "Phosphate assimilation in Rhizobium (Sinorhizobium) meliloti:
RT identification of a pit-like gene.";
RL J. Bacteriol. 180:4219-4226(1998).
CC -!- FUNCTION: The RecF protein is involved in DNA metabolism; it is
CC required for DNA replication and normal SOS inducibility. RecF binds
CC preferentially to single-stranded, linear DNA. It also seems to bind
CC ATP (By similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the RecF family. {ECO:0000305}.
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DR EMBL; AL591688; CAC41575.1; -; Genomic_DNA.
DR EMBL; AF008187; AAB70169.2; -; Genomic_DNA.
DR RefSeq; NP_384294.1; NC_003047.1.
DR RefSeq; WP_003531898.1; NC_003047.1.
DR AlphaFoldDB; P56903; -.
DR SMR; P56903; -.
DR STRING; 266834.SMc02863; -.
DR PRIDE; P56903; -.
DR EnsemblBacteria; CAC41575; CAC41575; SMc02863.
DR GeneID; 61601667; -.
DR KEGG; sme:SMc02863; -.
DR PATRIC; fig|266834.11.peg.1550; -.
DR eggNOG; COG1195; Bacteria.
DR HOGENOM; CLU_040267_2_0_5; -.
DR OMA; GESWSYA; -.
DR Proteomes; UP000001976; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003697; F:single-stranded DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-UniRule.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR GO; GO:0009432; P:SOS response; IEA:UniProtKB-UniRule.
DR Gene3D; 1.20.1050.90; -; 1.
DR Gene3D; 3.40.50.300; -; 1.
DR HAMAP; MF_00365; RecF; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR001238; DNA-binding_RecF.
DR InterPro; IPR018078; DNA-binding_RecF_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR003395; RecF/RecN/SMC_N.
DR InterPro; IPR042174; RecF_2.
DR PANTHER; PTHR32182:SF0; PTHR32182:SF0; 1.
DR Pfam; PF02463; SMC_N; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR TIGRFAMs; TIGR00611; recf; 1.
DR PROSITE; PS00617; RECF_1; 1.
DR PROSITE; PS00618; RECF_2; 1.
PE 3: Inferred from homology;
KW ATP-binding; Cytoplasm; DNA damage; DNA repair; DNA replication;
KW DNA-binding; Nucleotide-binding; Reference proteome; SOS response.
FT CHAIN 1..374
FT /note="DNA replication and repair protein RecF"
FT /id="PRO_0000196448"
FT BINDING 34..41
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255"
FT CONFLICT 169..176
FT /note="RNRLLSEF -> ATGFSRNS (in Ref. 2; AAB70169)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 374 AA; 40596 MW; E81F5B937ED05B55 CRC64;
MPHKVFLTRL KLSDFRNYAT LALDLDQRHV VLTGENGAGK TNLMEGVSFL SPGRGLRRAA
YADVARVGAP DGFSVFAAVD GMEGSVEIGT GTQGTEEGQS RRLRINGTAA RTVDELTDHL
RVLWLTPAMD GLFTGPSADR RRFLDRLVLS LDPEHGRRAS EFDRAMRSRN RLLSEFRPDP
AWLSAIEREM AGLGISMALA RQEMLGLLSA LVERSRSDGT FPSASLSLAG FLDDCAGIPA
FELEERYLAM LAEGRARDAA AGRTLDGPHR SDLLIRHREK DIEAERCSTG EQKALLVGLV
LAHARLVGDM TGHAPVLLLD EIAAHLDQGR RAALFDLVDG LGGQSFMTGT DRAMFDALGE
RAQYLAVANG RVSG
