RECF_RICFE
ID RECF_RICFE Reviewed; 364 AA.
AC Q4UNG8;
DT 16-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT 16-MAY-2006, sequence version 2.
DT 03-AUG-2022, entry version 89.
DE RecName: Full=DNA replication and repair protein RecF {ECO:0000255|HAMAP-Rule:MF_00365};
GN Name=recF {ECO:0000255|HAMAP-Rule:MF_00365}; OrderedLocusNames=RF_0035;
OS Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales;
OC Rickettsiaceae; Rickettsieae; Rickettsia; spotted fever group.
OX NCBI_TaxID=315456;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC VR-1525 / URRWXCal2;
RX PubMed=15984913; DOI=10.1371/journal.pbio.0030248;
RA Ogata H., Renesto P., Audic S., Robert C., Blanc G., Fournier P.-E.,
RA Parinello H., Claverie J.-M., Raoult D.;
RT "The genome sequence of Rickettsia felis identifies the first putative
RT conjugative plasmid in an obligate intracellular parasite.";
RL PLoS Biol. 3:1-12(2005).
CC -!- FUNCTION: The RecF protein is involved in DNA metabolism; it is
CC required for DNA replication and normal SOS inducibility. RecF binds
CC preferentially to single-stranded, linear DNA. It also seems to bind
CC ATP. {ECO:0000255|HAMAP-Rule:MF_00365}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00365}.
CC -!- SIMILARITY: Belongs to the RecF family. {ECO:0000255|HAMAP-
CC Rule:MF_00365}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAY60886.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; CP000053; AAY60886.1; ALT_INIT; Genomic_DNA.
DR RefSeq; WP_039594752.1; NC_007109.1.
DR AlphaFoldDB; Q4UNG8; -.
DR SMR; Q4UNG8; -.
DR STRING; 315456.RF_0035; -.
DR PRIDE; Q4UNG8; -.
DR EnsemblBacteria; AAY60886; AAY60886; RF_0035.
DR KEGG; rfe:RF_0035; -.
DR eggNOG; COG1195; Bacteria.
DR HOGENOM; CLU_040267_2_0_5; -.
DR OrthoDB; 891841at2; -.
DR Proteomes; UP000008548; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003697; F:single-stranded DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-UniRule.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR GO; GO:0009432; P:SOS response; IEA:UniProtKB-UniRule.
DR Gene3D; 1.20.1050.90; -; 1.
DR Gene3D; 3.40.50.300; -; 1.
DR HAMAP; MF_00365; RecF; 1.
DR InterPro; IPR001238; DNA-binding_RecF.
DR InterPro; IPR018078; DNA-binding_RecF_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR003395; RecF/RecN/SMC_N.
DR InterPro; IPR042174; RecF_2.
DR PANTHER; PTHR32182:SF0; PTHR32182:SF0; 1.
DR Pfam; PF02463; SMC_N; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR TIGRFAMs; TIGR00611; recf; 1.
DR PROSITE; PS00617; RECF_1; 1.
DR PROSITE; PS00618; RECF_2; 1.
PE 3: Inferred from homology;
KW ATP-binding; Cytoplasm; DNA damage; DNA repair; DNA replication;
KW DNA-binding; Nucleotide-binding; SOS response.
FT CHAIN 1..364
FT /note="DNA replication and repair protein RecF"
FT /id="PRO_0000236138"
FT BINDING 33..40
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00365"
SQ SEQUENCE 364 AA; 41857 MW; CC7E4DA8672E61EE CRC64;
MKNIFLHSLT LENYRNFKNL ELKTDNTPII LIGENGSGKT NILEAISLFY PGRGLRSAKL
ADICKASEDQ CLVKALLQSK LGLAEFTTQF KRSSNRRITE YNESKIANNE LSKFTSMVWL
TPQMEGIFTS GSSDRRKFLD RIVYNFDSKH AELVSKYEYY MYERNKILAE DIRDDNWLKI
IEEKMADMSS HIANNRLKTL EFMQQAIDEL ENEFPKADLS IDGIVEQKIL DGKENIVNFI
TAELYQTRSK DKLLGRTSFG VHKSDFLVKH QKKNILAKFC STGEQKAILI AIILAEMNYA
IKLTKIAPIL LLDEVFVHLD DKRRGYLIEF FTGLNMQLWV TATDLEGIEN FANKAQLIKL
PIIL
