ID   RECF_STAAU              Reviewed;         370 AA.
AC   P68863; P29232;
DT   21-DEC-2004, integrated into UniProtKB/Swiss-Prot.
DT   21-DEC-2004, sequence version 1.
DT   03-AUG-2022, entry version 94.
DE   RecName: Full=DNA replication and repair protein RecF;
GN   Name=recF;
OS   Staphylococcus aureus.
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=1280;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=YB886;
RX   PubMed=7898435; DOI=10.1007/bf00290713;
RA   Alonso J.C., Fisher L.M.;
RT   "Nucleotide sequence of the recF gene cluster from Staphylococcus aureus
RT   and complementation analysis in Bacillus subtilis recF mutants.";
RL   Mol. Gen. Genet. 246:680-686(1995).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 267-370.
RX   PubMed=1311298; DOI=10.1128/jb.174.5.1596-1603.1992;
RA   Margerrison E.E.C., Hopewell R., Fisher L.M.;
RT   "Nucleotide sequence of the Staphylococcus aureus gyrB-gyrA locus encoding
RT   the DNA gyrase A and B proteins.";
RL   J. Bacteriol. 174:1596-1603(1992).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 282-370.
RC   STRAIN=601055;
RX   PubMed=8388872; DOI=10.1128/jb.175.11.3269-3277.1993;
RA   Brockbank S.M.V., Barth P.T.;
RT   "Cloning, sequencing, and expression of the DNA gyrase genes from
RT   Staphylococcus aureus.";
RL   J. Bacteriol. 175:3269-3277(1993).
CC   -!- FUNCTION: The RecF protein is involved in DNA metabolism; it is
CC       required for DNA replication and normal SOS inducibility. RecF binds
CC       preferentially to single-stranded, linear DNA. It also seems to bind
CC       ATP.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the RecF family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; M86227; AAA73950.1; -; Genomic_DNA.
DR   EMBL; X71437; CAA50569.1; -; Genomic_DNA.
DR   PIR; S54710; C40585.
DR   RefSeq; WP_000775113.1; NZ_WYDB01000001.1.
DR   AlphaFoldDB; P68863; -.
DR   SMR; P68863; -.
DR   OMA; GESWSYA; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003697; F:single-stranded DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-UniRule.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR   GO; GO:0009432; P:SOS response; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.20.1050.90; -; 1.
DR   Gene3D; 3.40.50.300; -; 1.
DR   HAMAP; MF_00365; RecF; 1.
DR   InterPro; IPR001238; DNA-binding_RecF.
DR   InterPro; IPR018078; DNA-binding_RecF_CS.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR003395; RecF/RecN/SMC_N.
DR   InterPro; IPR042174; RecF_2.
DR   PANTHER; PTHR32182:SF0; PTHR32182:SF0; 1.
DR   Pfam; PF02463; SMC_N; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00611; recf; 1.
DR   PROSITE; PS00617; RECF_1; 1.
DR   PROSITE; PS00618; RECF_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cytoplasm; DNA damage; DNA repair; DNA replication;
KW   DNA-binding; Nucleotide-binding; SOS response.
FT   CHAIN           1..370
FT                   /note="DNA replication and repair protein RecF"
FT                   /id="PRO_0000196461"
FT   BINDING         30..37
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255"
FT   CONFLICT        309..316
FT                   /note="EYPILLLD -> NIPSYYC (in Ref. 2; AAA73950)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   370 AA;  42415 MW;  2D6471A9483B1368 CRC64;
     MKLNTLQLEN YRNYDEVTLK CHPDVNILIG ENAQGKTNLL ESIYTLALAK SHRTSNDKEL
     IRFNADYAKI EGELSYRHGT MPLTMFITKK GKQVKVNHLE QSRLTQYIGH LNVVLFAPED
     LNIVKGSPQI RRRFIDMELG QISAVYLNDL AQYQRILKQK NNYLKQLQLG QKKDLTMLEV
     LNQQFAEYAM KVTDKRAHFI QELESLAKPI HAGITNDKEA LSLNYLPSLK FDYAQNEAAR
     LEEIMSILSD NMQREKERGI SLFGPHRDDI SFDVNGMDAQ TYGSQGQQRT TALSIKLAEI
     ELMNIEVGEY PILLLDDVLS ELDDSRQTHL LSTIQHKVQT FVTTTSVDGI DHEIMNNAKL
     YRINQGEIIK