ID   RECF_STRCO              Reviewed;         373 AA.
AC   P36176;
DT   01-JUN-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-1994, sequence version 1.
DT   03-AUG-2022, entry version 125.
DE   RecName: Full=DNA replication and repair protein RecF;
GN   Name=recF; OrderedLocusNames=SCO3876; ORFNames=SCH18.13c;
OS   Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145).
OC   Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
OC   Streptomyces; Streptomyces albidoflavus group.
OX   NCBI_TaxID=100226;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=A3(2) / NRRL B-16638;
RX   PubMed=7828880; DOI=10.1016/0378-1119(94)90628-9;
RA   Calcutt M.J.;
RT   "Gene organization in the dnaA-gyrA region of the Streptomyces coelicolor
RT   chromosome.";
RL   Gene 151:23-28(1994).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-471 / A3(2) / M145;
RX   PubMed=12000953; DOI=10.1038/417141a;
RA   Bentley S.D., Chater K.F., Cerdeno-Tarraga A.-M., Challis G.L.,
RA   Thomson N.R., James K.D., Harris D.E., Quail M.A., Kieser H., Harper D.,
RA   Bateman A., Brown S., Chandra G., Chen C.W., Collins M., Cronin A.,
RA   Fraser A., Goble A., Hidalgo J., Hornsby T., Howarth S., Huang C.-H.,
RA   Kieser T., Larke L., Murphy L.D., Oliver K., O'Neil S., Rabbinowitsch E.,
RA   Rajandream M.A., Rutherford K.M., Rutter S., Seeger K., Saunders D.,
RA   Sharp S., Squares R., Squares S., Taylor K., Warren T., Wietzorrek A.,
RA   Woodward J.R., Barrell B.G., Parkhill J., Hopwood D.A.;
RT   "Complete genome sequence of the model actinomycete Streptomyces coelicolor
RT   A3(2).";
RL   Nature 417:141-147(2002).
CC   -!- FUNCTION: The RecF protein is involved in DNA metabolism; it is
CC       required for DNA replication and normal SOS inducibility. RecF binds
CC       preferentially to single-stranded, linear DNA. It also seems to bind
CC       ATP (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the RecF family. {ECO:0000305}.
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DR   EMBL; L27063; AAA65213.1; -; Genomic_DNA.
DR   EMBL; AL939118; CAB92996.1; -; Genomic_DNA.
DR   PIR; T10967; T10967.
DR   RefSeq; NP_628063.1; NC_003888.3.
DR   RefSeq; WP_003975056.1; NZ_VNID01000003.1.
DR   AlphaFoldDB; P36176; -.
DR   SMR; P36176; -.
DR   STRING; 100226.SCO3876; -.
DR   GeneID; 1099312; -.
DR   KEGG; sco:SCO3876; -.
DR   PATRIC; fig|100226.15.peg.3949; -.
DR   eggNOG; COG1195; Bacteria.
DR   HOGENOM; CLU_040267_1_1_11; -.
DR   InParanoid; P36176; -.
DR   OMA; GESWSYA; -.
DR   PhylomeDB; P36176; -.
DR   Proteomes; UP000001973; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003697; F:single-stranded DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR   GO; GO:0000731; P:DNA synthesis involved in DNA repair; IBA:GO_Central.
DR   GO; GO:0006302; P:double-strand break repair; IBA:GO_Central.
DR   GO; GO:0009432; P:SOS response; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.20.1050.90; -; 1.
DR   Gene3D; 3.40.50.300; -; 1.
DR   HAMAP; MF_00365; RecF; 1.
DR   InterPro; IPR001238; DNA-binding_RecF.
DR   InterPro; IPR018078; DNA-binding_RecF_CS.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR003395; RecF/RecN/SMC_N.
DR   InterPro; IPR042174; RecF_2.
DR   PANTHER; PTHR32182:SF0; PTHR32182:SF0; 1.
DR   Pfam; PF02463; SMC_N; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00611; recf; 1.
DR   PROSITE; PS00617; RECF_1; 1.
DR   PROSITE; PS00618; RECF_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cytoplasm; DNA damage; DNA repair; DNA replication;
KW   DNA-binding; Nucleotide-binding; Reference proteome; SOS response.
FT   CHAIN           1..373
FT                   /note="DNA replication and repair protein RecF"
FT                   /id="PRO_0000196470"
FT   BINDING         30..37
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   373 AA;  40743 MW;  C49CF45717F95C84 CRC64;
     MHVTHLSLAD FRSYARVEVP LDPGVTAFVG PNGQGKTNLV EAVGYLATLG SHRVSSDAPL
     VRMGAERAVI RAQVRQGERQ QLIELELNPG RANRARVNRS SQVKPRDVLG IVRTVLFAPE
     DLALVKGDPG ERRRFLDELI TARSPRMAGV RSDYDRVLKQ RNTLLKSAAL ARRHGGRTMD
     LSTLDVWDQH LARAGAELLA QRLDLIASVQ PLADKAYEQL APGGGPVALE YKPSAPGEAH
     TREDLYEQLM AALAEARKQE IERGVTLVGP HRDDLLLKLG SLPAKGYASH GESWSYALAL
     RLASFDLLRA EGNEPVLVLD DVFAELDARR RERLAELVAP GEQVLVTAAV DDDVPHVLAG
     ARFTVAEGTV ERV