ID   RECF_SYNY3              Reviewed;         384 AA.
AC   P73532;
DT   15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1997, sequence version 1.
DT   03-AUG-2022, entry version 135.
DE   RecName: Full=DNA replication and repair protein RecF;
GN   Name=recF; OrderedLocusNames=sll1277;
OS   Synechocystis sp. (strain PCC 6803 / Kazusa).
OC   Bacteria; Cyanobacteria; Synechococcales; Merismopediaceae; Synechocystis;
OC   unclassified Synechocystis.
OX   NCBI_TaxID=1111708;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PCC 6803 / Kazusa;
RX   PubMed=8905231; DOI=10.1093/dnares/3.3.109;
RA   Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y.,
RA   Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T.,
RA   Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S.,
RA   Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT   "Sequence analysis of the genome of the unicellular cyanobacterium
RT   Synechocystis sp. strain PCC6803. II. Sequence determination of the entire
RT   genome and assignment of potential protein-coding regions.";
RL   DNA Res. 3:109-136(1996).
RN   [2]
RP   DISCUSSION OF SOS REGULON.
RC   STRAIN=PCC 6803 / Kazusa;
RX   PubMed=15225304; DOI=10.1111/j.1365-2958.2004.04100.x;
RA   Domain F., Houot L., Chauvat F., Cassier-Chauvat C.;
RT   "Function and regulation of the cyanobacterial genes lexA, recA and ruvB:
RT   LexA is critical to the survival of cells facing inorganic carbon
RT   starvation.";
RL   Mol. Microbiol. 53:65-80(2004).
CC   -!- FUNCTION: The RecF protein is involved in DNA metabolism; it is
CC       required for DNA replication. RecF binds preferentially to single-
CC       stranded, linear DNA. It also seems to bind ATP (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- MISCELLANEOUS: This bacterium is considerably more resistant to UV and
CC       gamma irradiation than E.coli; the E.coli-like SOS regulon model is not
CC       an appropriate model for DNA repair in this cyanobacterium.
CC       {ECO:0000305|PubMed:15225304}.
CC   -!- SIMILARITY: Belongs to the RecF family. {ECO:0000305}.
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DR   EMBL; BA000022; BAA17572.1; -; Genomic_DNA.
DR   PIR; S77238; S77238.
DR   AlphaFoldDB; P73532; -.
DR   SMR; P73532; -.
DR   IntAct; P73532; 3.
DR   STRING; 1148.1652652; -.
DR   PaxDb; P73532; -.
DR   EnsemblBacteria; BAA17572; BAA17572; BAA17572.
DR   KEGG; syn:sll1277; -.
DR   eggNOG; COG1195; Bacteria.
DR   InParanoid; P73532; -.
DR   OMA; GESWSYA; -.
DR   PhylomeDB; P73532; -.
DR   Proteomes; UP000001425; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003697; F:single-stranded DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR   GO; GO:0000731; P:DNA synthesis involved in DNA repair; IBA:GO_Central.
DR   GO; GO:0006302; P:double-strand break repair; IBA:GO_Central.
DR   GO; GO:0009432; P:SOS response; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.20.1050.90; -; 1.
DR   Gene3D; 3.40.50.300; -; 1.
DR   HAMAP; MF_00365; RecF; 1.
DR   InterPro; IPR001238; DNA-binding_RecF.
DR   InterPro; IPR018078; DNA-binding_RecF_CS.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR003395; RecF/RecN/SMC_N.
DR   InterPro; IPR042174; RecF_2.
DR   PANTHER; PTHR32182:SF0; PTHR32182:SF0; 1.
DR   Pfam; PF02463; SMC_N; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00611; recf; 1.
DR   PROSITE; PS00617; RECF_1; 1.
DR   PROSITE; PS00618; RECF_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cytoplasm; DNA replication; DNA-binding; Nucleotide-binding;
KW   Reference proteome.
FT   CHAIN           1..384
FT                   /note="DNA replication and repair protein RecF"
FT                   /id="PRO_0000196480"
FT   BINDING         30..37
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   384 AA;  43744 MW;  2BB4920F302C63F2 CRC64;
     MYLKKLYLRA FRNYLEEEVE FSAQKTILVG NNAQGKSNLL EAVELLATLK SHRTSRDQEL
     VLDGAANGQI KALLERQYSV AELEIDLRRS GRRNLRINQN QCRRQLDFLG CLNAVEFSCL
     DLDLVRGAPD CRRQWLDTLL TQLEPLYAHL LGQYQHIVKQ RNALLKSLRQ QWETGLALGE
     ESTASLSLWD QQLVEMGTRV VRRRARGLAR LAPLAQEWHG RISGGNETLT VTYQPNVTWV
     GDDPEVVHQA FLEKLAQRRS AELHLGTTVV GPHRDEVGFV LDDTPARTYG SQGQQRTLVL
     ALKLAELSLI ETVIGEPPLL LLDDVLAELD LDRQGQLLMA IEDRFQTLIT TTHLSRFDDR
     WRRSAQILKV NAGQLEERWP SEID