ID   RECJ_HAEIN              Reviewed;         575 AA.
AC   P45112;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   03-AUG-2022, entry version 107.
DE   RecName: Full=Single-stranded-DNA-specific exonuclease RecJ;
DE            EC=3.1.-.-;
GN   Name=recJ; OrderedLocusNames=HI_1214;
OS   Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Haemophilus.
OX   NCBI_TaxID=71421;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX   PubMed=7542800; DOI=10.1126/science.7542800;
RA   Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F.,
RA   Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M.,
RA   McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D.,
RA   Scott J.D., Shirley R., Liu L.-I., Glodek A., Kelley J.M., Weidman J.F.,
RA   Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R.,
RA   Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D.,
RA   Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A.,
RA   Small K.V., Fraser C.M., Smith H.O., Venter J.C.;
RT   "Whole-genome random sequencing and assembly of Haemophilus influenzae
RT   Rd.";
RL   Science 269:496-512(1995).
CC   -!- FUNCTION: Single-stranded-DNA-specific exonuclease. Required for many
CC       types of recombinational events, although the stringency of the
CC       requirement for RecJ appears to vary with the type of recombinational
CC       event monitored and the other recombination gene products which are
CC       available (By similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the RecJ family. {ECO:0000305}.
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DR   EMBL; L42023; AAC22867.1; -; Genomic_DNA.
DR   PIR; F64110; F64110.
DR   RefSeq; NP_439370.1; NC_000907.1.
DR   RefSeq; WP_005694232.1; NC_000907.1.
DR   AlphaFoldDB; P45112; -.
DR   SMR; P45112; -.
DR   STRING; 71421.HI_1214; -.
DR   EnsemblBacteria; AAC22867; AAC22867; HI_1214.
DR   KEGG; hin:HI_1214; -.
DR   PATRIC; fig|71421.8.peg.1266; -.
DR   eggNOG; COG0608; Bacteria.
DR   HOGENOM; CLU_009736_5_1_6; -.
DR   OMA; FIICDHH; -.
DR   PhylomeDB; P45112; -.
DR   BioCyc; HINF71421:G1GJ1-1245-MON; -.
DR   Proteomes; UP000000579; Chromosome.
DR   GO; GO:0008409; F:5'-3' exonuclease activity; IEA:InterPro.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR   GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR   InterPro; IPR001667; DDH_dom.
DR   InterPro; IPR038763; DHH_sf.
DR   InterPro; IPR003156; DHHA1_dom.
DR   InterPro; IPR004610; RecJ.
DR   InterPro; IPR041122; RecJ_OB.
DR   Pfam; PF01368; DHH; 1.
DR   Pfam; PF02272; DHHA1; 1.
DR   Pfam; PF17768; RecJ_OB; 1.
DR   SUPFAM; SSF64182; SSF64182; 1.
DR   TIGRFAMs; TIGR00644; recJ; 1.
PE   3: Inferred from homology;
KW   Exonuclease; Hydrolase; Nuclease; Reference proteome.
FT   CHAIN           1..575
FT                   /note="Single-stranded-DNA-specific exonuclease RecJ"
FT                   /id="PRO_0000097230"
SQ   SEQUENCE   575 AA;  64219 MW;  B1CE80039BBEF208 CRC64;
     MKKLIKRREI PIGNSVSNHP LLDRLYRARH IQNTKELDRT LKSMLNPNQL YGIEQAVNLL
     VEAYQPQQKI VIVGDFDADG ATSTALSVLA LRQLGFSDVD YLVPNRFEQG YGLSIPVAEM
     AIEKGVQLLM TVDNGVSSFD GVAFLKEKGI RVLVTDHHLP PETLPPADAI VNPNLSQCGF
     PSKSLAGVGV AFYLMLAVRA KFRELGIFTA ETQPNFTDLL DLVALGTIAD VVPLDQNNRI
     LAYQGLMRIR ARHCRLGIIA LAEVANRNVE QFTSSDLGFC IGPRLNAAGR LDNMSIGVEL
     LLANEMSKAR ELALDLDQLN QTRKEIEAGM KLEAIKICQN LTALFKELPY GITLYQPDWH
     QGVLGIVSSR IKDQYHRPVI AFAQDSEGIL KGSARSIEGL HMRDVLERIH SQHPNMILKF
     GGHAMAAGLS IREEHFADFQ HIFNQTVADW LDEEHLQGVI WTDGELNSNE FNLETAELIK
     SVGTWGQGFP EPCFDGEFKI LDQRAIGQNK NHLKMLLEPK QGGVLLDAIA FNINTRLYPD
     LSIKQARLAY KLEINEFRGN RSLQLLVDYI EPIDE