ID   RECN_AQUAE              Reviewed;         520 AA.
AC   O66834;
DT   01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1998, sequence version 1.
DT   03-AUG-2022, entry version 111.
DE   RecName: Full=DNA repair protein RecN;
DE   AltName: Full=Recombination protein N;
GN   Name=recN; OrderedLocusNames=aq_561;
OS   Aquifex aeolicus (strain VF5).
OC   Bacteria; Aquificae; Aquificales; Aquificaceae; Aquifex.
OX   NCBI_TaxID=224324;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=VF5;
RX   PubMed=9537320; DOI=10.1038/32831;
RA   Deckert G., Warren P.V., Gaasterland T., Young W.G., Lenox A.L.,
RA   Graham D.E., Overbeek R., Snead M.A., Keller M., Aujay M., Huber R.,
RA   Feldman R.A., Short J.M., Olsen G.J., Swanson R.V.;
RT   "The complete genome of the hyperthermophilic bacterium Aquifex aeolicus.";
RL   Nature 392:353-358(1998).
CC   -!- FUNCTION: May be involved in recombinational repair of damaged DNA.
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the RecN family. {ECO:0000305}.
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DR   EMBL; AE000657; AAC06789.1; -; Genomic_DNA.
DR   PIR; F70350; F70350.
DR   RefSeq; NP_213394.1; NC_000918.1.
DR   RefSeq; WP_010880332.1; NC_000918.1.
DR   AlphaFoldDB; O66834; -.
DR   SMR; O66834; -.
DR   STRING; 224324.aq_561; -.
DR   EnsemblBacteria; AAC06789; AAC06789; aq_561.
DR   KEGG; aae:aq_561; -.
DR   PATRIC; fig|224324.8.peg.460; -.
DR   eggNOG; COG0497; Bacteria.
DR   HOGENOM; CLU_018297_3_1_0; -.
DR   InParanoid; O66834; -.
DR   OMA; QVICVTH; -.
DR   OrthoDB; 1074831at2; -.
DR   Proteomes; UP000000798; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR   GO; GO:0000724; P:double-strand break repair via homologous recombination; IBA:GO_Central.
DR   GO; GO:0009314; P:response to radiation; IBA:GO_Central.
DR   GO; GO:0009432; P:SOS response; IBA:GO_Central.
DR   Gene3D; 3.40.50.300; -; 2.
DR   InterPro; IPR004604; DNA_recomb/repair_RecN.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR038729; Rad50/SbcC_AAA.
DR   PANTHER; PTHR11059; PTHR11059; 1.
DR   Pfam; PF13476; AAA_23; 1.
DR   PIRSF; PIRSF003128; RecN; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00634; recN; 1.
PE   3: Inferred from homology;
KW   ATP-binding; DNA damage; DNA repair; Nucleotide-binding;
KW   Reference proteome.
FT   CHAIN           1..520
FT                   /note="DNA repair protein RecN"
FT                   /id="PRO_0000188012"
FT   BINDING         29..36
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   520 AA;  60440 MW;  A9708562ACBE901E CRC64;
     MLGRLYIQNF FFIRDVEVEF ERGLNVITGE TGTGKSMTIS AIEFLMGKQG DYPEGTAVEL
     ELLGEEEIIL RREVKKGRSR YYVNGKGASK STVLELLEGK ISLQGQNEFI NLFREDFQRK
     LLDTFANLND KVKELEKVYN SLRKKEQELF EFLRKKEELI QKKDYLEFRV REVEEIGISS
     EEYEELKNKA NLINNLEKVK KAVGESLYKL LEGENSVYEI LGEIRKNLAK VESYSGKFSE
     LIEKIANLEE EVYELYNSLK EEMPEISEEE VNEINEKLFR IQRLEEKYKK SFPEILKEVE
     EIKEELSNLN SVDFKEEELR EEVEKLREEY DKLAEEVSRD RRKKAEDLEE RIEEILKELN
     LERAKLKVEI KESEPTKYGK DKIEFLFSSY GKDFKPLEEV ASGGELSRLF LALSLILPAS
     ETYVFDEVDA GISGETSFKV AKFLKELSKK MQVIVITHSA PLCAAGDKNF KTEKKFLGDI
     PYIVVRELSE EEKVEEVARL MGMKSEKTLE GAKELVEAFK