RECN_DEIRA
ID RECN_DEIRA Reviewed; 564 AA.
AC Q9WXF2;
DT 30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT 30-MAY-2000, sequence version 2.
DT 03-AUG-2022, entry version 117.
DE RecName: Full=DNA repair protein RecN;
DE AltName: Full=Recombination protein N;
GN Name=recN; OrderedLocusNames=DR_1477;
OS Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG
OS 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422).
OC Bacteria; Deinococcus-Thermus; Deinococci; Deinococcales; Deinococcaceae;
OC Deinococcus.
OX NCBI_TaxID=243230;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=KD8301;
RA Funayama T., Narumi I., Kikuchi M., Kitayama S., Watanabe H., Yamamoto K.;
RT "Deinococcus radiodurans recN gene: a molecular cloning and gene disruption
RT analysis.";
RL Submitted (FEB-1999) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB
RC 9279 / R1 / VKM B-1422;
RX PubMed=10567266; DOI=10.1126/science.286.5444.1571;
RA White O., Eisen J.A., Heidelberg J.F., Hickey E.K., Peterson J.D.,
RA Dodson R.J., Haft D.H., Gwinn M.L., Nelson W.C., Richardson D.L.,
RA Moffat K.S., Qin H., Jiang L., Pamphile W., Crosby M., Shen M.,
RA Vamathevan J.J., Lam P., McDonald L.A., Utterback T.R., Zalewski C.,
RA Makarova K.S., Aravind L., Daly M.J., Minton K.W., Fleischmann R.D.,
RA Ketchum K.A., Nelson K.E., Salzberg S.L., Smith H.O., Venter J.C.,
RA Fraser C.M.;
RT "Genome sequence of the radioresistant bacterium Deinococcus radiodurans
RT R1.";
RL Science 286:1571-1577(1999).
CC -!- FUNCTION: May be involved in recombinational repair of damaged DNA.
CC {ECO:0000250}.
CC -!- INTERACTION:
CC Q9WXF2; Q9WXF2: recN; NbExp=6; IntAct=EBI-16018526, EBI-16018526;
CC -!- SIMILARITY: Belongs to the RecN family. {ECO:0000305}.
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DR EMBL; AB023411; BAA76704.1; -; Genomic_DNA.
DR EMBL; AE000513; AAF11043.1; -; Genomic_DNA.
DR PIR; A75391; A75391.
DR RefSeq; NP_295200.1; NC_001263.1.
DR RefSeq; WP_010888116.1; NZ_CP015081.1.
DR PDB; 4ABX; X-ray; 2.04 A; A/B/C/D=196-364.
DR PDB; 4ABY; X-ray; 3.00 A; A/B/C/D=1-195, A/B/C/D=365-564.
DR PDB; 4AD8; X-ray; 4.00 A; A=1-237, A=305-564.
DR PDBsum; 4ABX; -.
DR PDBsum; 4ABY; -.
DR PDBsum; 4AD8; -.
DR AlphaFoldDB; Q9WXF2; -.
DR SMR; Q9WXF2; -.
DR DIP; DIP-59988N; -.
DR STRING; 243230.DR_1477; -.
DR EnsemblBacteria; AAF11043; AAF11043; DR_1477.
DR KEGG; dra:DR_1477; -.
DR PATRIC; fig|243230.17.peg.1677; -.
DR eggNOG; COG0497; Bacteria.
DR HOGENOM; CLU_018297_3_0_0; -.
DR InParanoid; Q9WXF2; -.
DR OMA; QVICVTH; -.
DR OrthoDB; 1074831at2; -.
DR Proteomes; UP000002524; Chromosome I.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR GO; GO:0000724; P:double-strand break repair via homologous recombination; IBA:GO_Central.
DR GO; GO:0009314; P:response to radiation; IBA:GO_Central.
DR GO; GO:0009432; P:SOS response; IBA:GO_Central.
DR Gene3D; 3.40.50.300; -; 2.
DR InterPro; IPR004604; DNA_recomb/repair_RecN.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR003395; RecF/RecN/SMC_N.
DR PANTHER; PTHR11059; PTHR11059; 1.
DR Pfam; PF02463; SMC_N; 1.
DR PIRSF; PIRSF003128; RecN; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR TIGRFAMs; TIGR00634; recN; 1.
PE 1: Evidence at protein level;
KW 3D-structure; ATP-binding; DNA damage; DNA repair; Nucleotide-binding;
KW Reference proteome.
FT CHAIN 1..564
FT /note="DNA repair protein RecN"
FT /id="PRO_0000188016"
FT REGION 1..32
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 61..68
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255"
FT STRAND 36..42
FT /evidence="ECO:0007829|PDB:4ABY"
FT STRAND 45..51
FT /evidence="ECO:0007829|PDB:4ABY"
FT STRAND 54..62
FT /evidence="ECO:0007829|PDB:4ABY"
FT HELIX 63..70
FT /evidence="ECO:0007829|PDB:4ABY"
FT HELIX 72..77
FT /evidence="ECO:0007829|PDB:4ABY"
FT HELIX 84..86
FT /evidence="ECO:0007829|PDB:4ABY"
FT STRAND 92..99
FT /evidence="ECO:0007829|PDB:4ABY"
FT STRAND 110..116
FT /evidence="ECO:0007829|PDB:4ABY"
FT STRAND 121..125
FT /evidence="ECO:0007829|PDB:4ABY"
FT STRAND 128..130
FT /evidence="ECO:0007829|PDB:4ABY"
FT HELIX 132..139
FT /evidence="ECO:0007829|PDB:4ABY"
FT TURN 140..142
FT /evidence="ECO:0007829|PDB:4ABY"
FT STRAND 143..146
FT /evidence="ECO:0007829|PDB:4ABY"
FT TURN 147..149
FT /evidence="ECO:0007829|PDB:4ABY"
FT TURN 151..154
FT /evidence="ECO:0007829|PDB:4ABY"
FT HELIX 157..165
FT /evidence="ECO:0007829|PDB:4ABY"
FT HELIX 169..191
FT /evidence="ECO:0007829|PDB:4ABY"
FT HELIX 196..216
FT /evidence="ECO:0007829|PDB:4ABX"
FT TURN 220..222
FT /evidence="ECO:0007829|PDB:4ABX"
FT HELIX 223..250
FT /evidence="ECO:0007829|PDB:4ABX"
FT STRAND 253..255
FT /evidence="ECO:0007829|PDB:4ABX"
FT HELIX 257..272
FT /evidence="ECO:0007829|PDB:4ABX"
FT HELIX 276..304
FT /evidence="ECO:0007829|PDB:4ABX"
FT HELIX 310..330
FT /evidence="ECO:0007829|PDB:4ABX"
FT HELIX 334..358
FT /evidence="ECO:0007829|PDB:4ABX"
FT HELIX 365..398
FT /evidence="ECO:0007829|PDB:4ABY"
FT TURN 399..402
FT /evidence="ECO:0007829|PDB:4ABY"
FT STRAND 407..419
FT /evidence="ECO:0007829|PDB:4ABY"
FT STRAND 422..435
FT /evidence="ECO:0007829|PDB:4ABY"
FT HELIX 441..443
FT /evidence="ECO:0007829|PDB:4ABY"
FT HELIX 447..461
FT /evidence="ECO:0007829|PDB:4ABY"
FT STRAND 464..472
FT /evidence="ECO:0007829|PDB:4ABY"
FT TURN 473..476
FT /evidence="ECO:0007829|PDB:4ABY"
FT HELIX 479..492
FT /evidence="ECO:0007829|PDB:4ABY"
FT TURN 493..495
FT /evidence="ECO:0007829|PDB:4ABY"
FT STRAND 496..501
FT /evidence="ECO:0007829|PDB:4ABY"
FT HELIX 505..508
FT /evidence="ECO:0007829|PDB:4ABY"
FT STRAND 512..522
FT /evidence="ECO:0007829|PDB:4ABY"
FT STRAND 525..532
FT /evidence="ECO:0007829|PDB:4ABY"
FT HELIX 536..547
FT /evidence="ECO:0007829|PDB:4ABY"
FT HELIX 552..562
FT /evidence="ECO:0007829|PDB:4ABY"
SQ SEQUENCE 564 AA; 59799 MW; AA620A2C2F0F615F CRC64;
MTRKARTPKA APVPEAVAVV EPPPPDAAPT GPRLSRLEIR NLATITQLEL ELGGGFCAFT
GETGAGKSII VDALGLLLGG RANHDLIRSG EKELLVTGFW GDGDESEADS ASRRLSSAGR
GAARLSGEVV SVRELQEWAQ GRLTIHWQHS AVSLLSPANQ RGLLDRRVTK EAQAYAAAHA
AWREAVSRLE RLQASQRERA RQIDLLAFQV QEISEVSPDP GEEEGLNTEL SRLSNLHTIA
QAAAGGVELL SDGDLNAAGL IGEAVRALNA GAKYDETVMQ LQNELRAALE SVQAIAGELR
DVAEGSAADP EALDRVEARL SALSKLKNKY GPTLEDVVEF GAQAAEELAG LEEDERDAGS
LQADVDALHA ELLKVGQALD AAREREAEPL VDSLLAVIRE LGMPHARMEF ALSALAEPAA
YGLSDVLLRF SANPGEELGP LSDVASGGEL SRVMLAVSTV LGADTPSVVF DEVDAGIGGA
AAIAVAEQLS RLADTRQVLV VTHLAQIAAR AHHHYKVEKQ VEDGRTVSHV RLLTGDERLE
EIARMLSGNT SEAALEHARE LLAG
