RECN_HAEIN
ID RECN_HAEIN Reviewed; 558 AA.
AC P44496;
DT 01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1995, sequence version 1.
DT 03-AUG-2022, entry version 112.
DE RecName: Full=DNA repair protein RecN;
DE AltName: Full=Recombination protein N;
GN Name=recN; OrderedLocusNames=HI_0070;
OS Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC Pasteurellaceae; Haemophilus.
OX NCBI_TaxID=71421;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX PubMed=7542800; DOI=10.1126/science.7542800;
RA Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F.,
RA Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M.,
RA McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D.,
RA Scott J.D., Shirley R., Liu L.-I., Glodek A., Kelley J.M., Weidman J.F.,
RA Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R.,
RA Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D.,
RA Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A.,
RA Small K.V., Fraser C.M., Smith H.O., Venter J.C.;
RT "Whole-genome random sequencing and assembly of Haemophilus influenzae
RT Rd.";
RL Science 269:496-512(1995).
CC -!- FUNCTION: May be involved in recombinational repair of damaged DNA.
CC {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the RecN family. {ECO:0000305}.
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DR EMBL; L42023; AAC21748.1; -; Genomic_DNA.
DR PIR; H64046; H64046.
DR RefSeq; NP_438243.1; NC_000907.1.
DR RefSeq; WP_005693852.1; NC_000907.1.
DR AlphaFoldDB; P44496; -.
DR SMR; P44496; -.
DR STRING; 71421.HI_0070; -.
DR EnsemblBacteria; AAC21748; AAC21748; HI_0070.
DR KEGG; hin:HI_0070; -.
DR PATRIC; fig|71421.8.peg.71; -.
DR eggNOG; COG0497; Bacteria.
DR HOGENOM; CLU_018297_3_1_6; -.
DR OMA; QVICVTH; -.
DR PhylomeDB; P44496; -.
DR BioCyc; HINF71421:G1GJ1-71-MON; -.
DR Proteomes; UP000000579; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0000724; P:double-strand break repair via homologous recombination; IBA:GO_Central.
DR GO; GO:0009314; P:response to radiation; IBA:GO_Central.
DR GO; GO:0009432; P:SOS response; EXP:CollecTF.
DR Gene3D; 3.40.50.300; -; 2.
DR InterPro; IPR004604; DNA_recomb/repair_RecN.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR003395; RecF/RecN/SMC_N.
DR PANTHER; PTHR11059; PTHR11059; 1.
DR Pfam; PF02463; SMC_N; 1.
DR PIRSF; PIRSF003128; RecN; 1.
DR SUPFAM; SSF52540; SSF52540; 2.
DR TIGRFAMs; TIGR00634; recN; 1.
PE 3: Inferred from homology;
KW ATP-binding; DNA damage; DNA repair; Nucleotide-binding;
KW Reference proteome.
FT CHAIN 1..558
FT /note="DNA repair protein RecN"
FT /id="PRO_0000188018"
FT BINDING 29..36
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255"
SQ SEQUENCE 558 AA; 62634 MW; 6C573A656FA72387 CRC64;
MLTQLTINNF AIVRQLDIEL AKGMSVITGE TGAGKSIAID ALGLCFGQRV ETSMVREGQE
RAEICATFQL ESQNPAYHWL SEQELQDPDN PTECILRRII NADGRSKAFI NSTPVSASQL
KEIAQYLVHI NGQHASQLLL KNDYQLQLVD NFAAHPELLV KMREDYQTWK NLQNQVKTFQ
QKVAENEARK QLLQYQVDEL DEFNLRPNEY LELEDEQRRL SSSEQLTQLS QSALQILSEN
DTVNIDSLLY RATQYIDELA ELDPQYAEVQ NMLNDALIQV QEATSEVQNL SSNIEQDPQL
LQEIEQRISQ TLQLARKHQV KPEDLVEQHK KLKAELTALL DFSESEEMLI EQEKRAFEQM
QATATALTAS RQQSATRLAQ NVTQSIKQLA MENAEFYVEL NTDLDKVSAN GADNVIFTLR
SNLGQQPQPL AKIASGGELS RISLAIQVLT SDQSAIPTLI FDEVDVGISG KTASVVGKLL
RQLSERCQVL CVTHLPQVAC HGHHQFNVEK FTVDNKTETK MTALSQAERV PALARLLGGS
EITELALANA QEMLDLVH